Search Results - "Boyarchuk, Ekaterina"
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Sound of silence: the properties and functions of repressive Lys methyltransferases
Published in Nature reviews. Molecular cell biology (01-08-2015)“…Key Points Lys methyltransferases (KMTs) belong to a large protein family that is characterized by the presence of the conserved catalytic SET domain. By using…”
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Histone variant H3.3 residue S31 is essential for Xenopus gastrulation regardless of the deposition pathway
Published in Nature communications (09-03-2020)“…Vertebrates exhibit specific requirements for replicative H3 and non-replicative H3.3 variants during development. To disentangle whether this involves…”
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Two HIRA-dependent pathways mediate H3.3 de novo deposition and recycling during transcription
Published in Nature structural & molecular biology (01-11-2020)“…Nucleosomes represent a challenge in regard to transcription. Histone eviction enables RNA polymerase II (RNAPII) progression through DNA, but compromises…”
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Functional activity of the H3.3 histone chaperone complex HIRA requires trimerization of the HIRA subunit
Published in Nature communications (06-08-2018)“…The HIRA histone chaperone complex deposits the histone variant H3.3 onto chromatin in a DNA synthesis-independent manner. It comprises three identified…”
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High-resolution visualization of H3 variants during replication reveals their controlled recycling
Published in Nature communications (09-08-2018)“…DNA replication is a challenge for the faithful transmission of parental information to daughter cells, as both DNA and chromatin organization must be…”
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Xenopus HJURP and condensin II are required for CENP-A assembly
Published in The Journal of cell biology (21-02-2011)“…Centromeric protein A (CENP-A) is the epigenetic mark of centromeres. CENP-A replenishment is necessary in each cell cycle to compensate for the dilution…”
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Pericentric heterochromatin state during the cell cycle controls the histone variant composition of centromeres
Published in Journal of cell science (01-01-2014)“…Correct chromosome segregation requires a unique chromatin environment at centromeres and in their vicinity. Here, we address how the deposition of canonical…”
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ZBTB24 is a conserved multifaceted transcription factor at genes and centromeres that governs the DNA methylation state and expression of satellite repeats
Published in Human molecular genetics (20-11-2024)“…Abstract Since its discovery as a causative gene of the Immunodeficiency with Centromeric instability and Facial anomalies syndrome, ZBTB24 has emerged as a…”
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The histone variant composition of centromeres is controlled by the pericentric heterochromatin state during the cell cycle
Published in Journal of cell science (01-08-2014)“…Correct chromosome segregation requires a unique chromatin environment at centromeres and in their vicinity. Here, we address how the deposition of canonical…”
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Unexpected Distinct Roles of the Related Histone H3 Lysine 9 Methyltransferases G9a and G9a-Like Protein in Myoblasts
Published in Journal of molecular biology (05-06-2016)“…Lysine methyltransferases G9a and GLP (G9a-like protein) are highly homologous and form functional heterodimeric complexes that establish mono- and…”
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Cell cycle dynamics of histone variants at the centromere, a model for chromosomal landmarks
Published in Current opinion in cell biology (01-06-2011)“…Classical heterochromatin chromosomal landmarks, such as centromeres and telomeres, are characterized by specific chromatin signatures. Among these, the…”
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SETDB1 modulates the TGFβ response in Duchenne muscular dystrophy myotubes
Published in Science advances (03-05-2024)“…Overactivation of the transforming growth factor-β (TGFβ) signaling in Duchenne muscular dystrophy (DMD) is a major hallmark of disease progression, leading to…”
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SETDB1 modulates the TGFβ response in Duchenne muscular dystrophy myotubes
Published in Science advances (03-05-2024)“…Overactivation of the transforming growth factor-β (TGFβ) signaling in Duchenne muscular dystrophy (DMD) is a major hallmark of disease progression, leading to…”
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Identification of MyoD Interactome Using Tandem Affinity Purification Coupled to Mass Spectrometry
Published in Journal of visualized experiments (17-05-2016)“…Skeletal muscle terminal differentiation starts with the commitment of pluripotent mesodermal precursor cells to myoblasts. These cells have still the ability…”
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Identification of MyoD Interactome Using Tandem Affinity Purification Coupled to Mass Spectrometry
Published in Journal of visualized experiments (17-05-2016)Get full text
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Xenopus HJURP and condensin II are required for CENP-A assembly
Published in The Journal of cell biology (21-02-2011)“…Centromeric protein A (CENP-A) is the epigenetic mark of centromeres. CENP-A replenishment is necessary in each cell cycle to compensate for the dilution…”
Get full text
Journal Article -
17
Xenopus HJURP and condensin II are required for CENP-A assembly
Published in The Journal of cell biology (07-03-2011)Get full text
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