Search Results - "Boyapati, Ray"

Systematic Review of Effects of Withdrawal of Immunomodulators or Biologic Agents From Patients With Inflammatory Bowel Disease by Torres, Joana, Boyapati, Ray K, Kennedy, Nicholas A, Louis, Edouard, Colombel, Jean-Frédéric, Satsangi, Jack

“…Little is known about the optimal duration of therapy with an anti–tumor necrosis factor (TNF) agent and/or an immunomodulator for patients with inflammatory…”
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Biomarkers in Search of Precision Medicine in IBD by Boyapati, Ray K, Kalla, Rahul, Satsangi, Jack, Ho, Gwo-Tzer

“…The completion of the human genome project in 2003 represented a major scientific landmark, ushering in a new era with hopes and expectations of fresh insights…”
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Mitochondrial DNA Is a Pro-Inflammatory Damage-Associated Molecular Pattern Released During Active IBD by Boyapati, Ray K, Dorward, David A, Tamborska, Arina, Kalla, Rahul, Ventham, Nicholas T, Doherty, Mary K, Whitfield, Philip D, Gray, Mohini, Loane, Joseph, Rossi, Adriano G, Satsangi, Jack, Ho, Gwo-tzer

“…Abstract Background Due to common evolutionary origins, mitochondrial DNA (mtDNA) shares many similarities with immunogenic bacterial DNA. MtDNA is recognized…”
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Vedolizumab for induction and maintenance of remission in Crohn's disease by Hui, Samuel, Sinopoulou, Vassiliki, Gordon, Morris, Aali, Ghazaleh, Krishna, Anuj, Ding, Nik Sheng, Boyapati, Ray K

“…Vedolizumab blocks inflammatory activity within the gastrointestinal tract. Systematic reviews have demonstrated the efficacy of vedolizumab in ulcerative…”
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Serum Calprotectin: A Novel Diagnostic and Prognostic Marker in Inflammatory Bowel Diseases by Kalla, Rahul, Kennedy, Nicholas A, Ventham, Nicholas T, Boyapati, Ray K, Adams, Alex T, Nimmo, Elaine R, Visconti, Micaela R, Drummond, Hazel, Ho, Gwo-Tzer, Pattenden, Rebecca J, Wilson, David C, Satsangi, Jack

“…There is an unmet need for novel blood-based biomarkers that offer timely and accurate diagnostic and prognostic testing in inflammatory bowel diseases (IBD)…”
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Advances in the understanding of mitochondrial DNA as a pathogenic factor in inflammatory diseases [version 1; peer review: 3 approved] by Boyapati, Ray K, Tamborska, Arina, Dorward, David A, Ho, Gwo-Tzer

“…Mitochondrial DNA (mtDNA) has many similarities with bacterial DNA because of their shared common ancestry. Increasing evidence demonstrates mtDNA to be a…”
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Characteristics of the Kono-S anastomosis in Crohn's disease patients using intestinal ultrasound by Low, Elizabeth Sl, Greeve, Tessa, Boyapati, Ray K, Moore, Gregory T, Shelton, Edward

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Risk stratification in acute upper GI bleeding: comparison of the AIMS65 score with the Glasgow-Blatchford and Rockall scoring systems by Robertson, Marcus, MBBS(Hons), Majumdar, Avik, MBBS(Hons), Boyapati, Ray, MBBS(Hons), Chung, William, MBBS, Worland, Tom, MBBS, Terbah, Ryma, MBBS, Wei, James, MBBS, Lontos, Steve, MBBS, MD, Angus, Peter, MBBS, MD, Vaughan, Rhys, MBBS, PhD

“…Background and Aims The American College of Gastroenterology recommends early risk stratification in patients presenting with upper GI bleeding (UGIB). The…”
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Withdrawal of immunosuppressant or biologic therapy for patients with quiescent Crohn's disease by Boyapati, Ray K, Torres, Joana, Palmela, Carolina, Parker, Claire E, Silverberg, Orli M, Upadhyaya, Sonam D, Nguyen, Tran M, Colombel, Jean-Frédéric

“…Crohn's disease (CD) is a chronic, relapsing and remitting disease of the gastrointestinal tract that can cause significant morbidity and disability. Current…”
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Bacillus Subtilis (BG01-4TM) Improves Self-Reported Symptoms for Constipation, Indigestion, and Dyspepsia: A Phase 1/2A Randomized Controlled Trial by Patch, Craig, Pearce, Alan J, Cheng, Mek, Boyapati, Ray, Brenna, J. Thomas

“…Background: Functional gastrointestinal disorders (FGIDs) are common, difficult-to-manage conditions. Probiotics are emerging as a dietary component that…”
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Can Thiopurines Prevent Formation of Antibodies Against Tumor Necrosis Factor Antagonists After Failure of These Therapies? by Boyapati, Ray K., MBBS, FRACP, Ho, Gwo-Tzer, PhD, FRCP, Satsangi, Jack, DPhil, FRCP

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Prevalence of NUDT15 Genetic Variants and Incidence of Thiopurine-induced Leukopenia in Inflammatory Bowel Disease: A Systematic Review and Meta-analysis by Yu, Natalie, Sriranganathan, Danujan, Walker, Gareth J, Sazonovs, Aleksejs, Wilding, Helen, Roberts, Christopher, Kennedy, Nicholas A, Ahmad, Tariq, Boyapati, Ray K, Ding, Nik S, Segal, Jonathan P

“…Abstract Background and Aims Nudix hydrolase 15 [NUDT15] genetic variants confer an increased risk of thiopurine-induced leukopenia [TIL]; however, their…”
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Characterisation of the Circulating Transcriptomic Landscape in Inflammatory Bowel Disease Provides Evidence for Dysregulation of Multiple Transcription Factors Including NFE2, SPI1, CEBPB, and IRF2 by Nowak, Jan K, Adams, Alex T, Kalla, Rahul, Lindstrøm, Jonas C, Vatn, Simen, Bergemalm, Daniel, Keita, Åsa V, Gomollón, Fernando, Jahnsen, Jørgen, Vatn, Morten H, Ricanek, Petr, Ostrowski, Jerzy, Walkowiak, Jaroslaw, Halfvarson, Jonas, Satsangi, Jack

“…Abstract Aim To assess the pathobiological and translational importance of whole-blood transcriptomic analysis in inflammatory bowel disease [IBD]. Methods We…”
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Controversies in Inflammatory Bowel Disease: Exploring Clinical Dilemmas Using Cochrane Reviews by East, James E, Boyapati, Ray K, Torres, Joana, Parker, Claire E, MacDonald, John K, Chande, Nilesh, Feagan, Brian G

“…Abstract A symposium organized by the Cochrane IBD Group and presented at the 2017 Digestive Disease Week annual meeting reviewed the recent literature on…”
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Mitochondrial DNA is a Damage-Associated Molecular Pattern (DAMP) Released during Active IBD Promoting TLR9-Mediated Inflammation by Boyapati, Ray K, Dorward, David, Tamborska, Arina, Kalla, Rahul, Ventham, Nicholas, Rossi, Adriano G, Satsangi, Jack, Ho, Gwo-tzer

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MDR1-Deficiency Unmasks Mitochondrial Dysfunction as a Pathogenic Mechanism in IBD by Ho, Gwo-tzer, Aird, Rhona, Boyapati, Ray K, Liu, Bo, Kennedy, Nicholas, Shimizu, Takahiko, Sartor, R. Balfour, Satsangi, Jack

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AIMS65: A promising upper gastrointestinal bleeding risk score but further validation required by Boyapati, Ray, Majumdar, Avik, Robertson, Marcus

“…A novel upper gastrointestinal bleeding risk stratification score(AIMS65) has recently been developed and validated. It has advantages over existing risk…”
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Precision medicine in inflammatory bowel disease: concept, progress and challenges [version 1; peer review: awaiting peer review] by Borg-Bartolo, Simon P, Boyapati, Ray Kiran, Satsangi, Jack, Kalla, Rahul

“…Crohn's disease and ulcerative colitis are increasingly prevalent, relapsing and remitting inflammatory bowel diseases (IBDs) with variable disease courses and…”
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One fifth of hospitalizations for peptic ulcer-related bleeding are potentially preventable by Boyapati, Ray, Ong, Sim Ye, Ye, Bei, Kruavit, Anuk, Lee, Nora, Vaughan, Rhys, Nandurkar, Sanjay, Gibson, Peter, Garg, Mayur

“…AIM:To calculate the proportion of potentially preventable hospitalizations due to peptic ulcer disease(PUD),erosive gastritis(EG)or…”
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Suspected acute hemolytic transfusion reaction mediated by anti-Di(a) by Bennett, Ashwini, Boyapati, Ray K, Hong, Frank S

“…Anti-Di(a) can mediate hemolytic disease of the fetus and newborn, but it is unclear if it can cause hemolytic transfusion reactions (HTRs). To date, there has…”
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