Search Results - "Boyaci, Hande"

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  1. 1

    Diverse and unified mechanisms of transcription initiation in bacteria by Chen, James, Boyaci, Hande, Campbell, Elizabeth A.

    Published in Nature reviews. Microbiology (01-02-2021)
    “…Transcription of DNA is a fundamental process in all cellular organisms. The enzyme responsible for transcription, RNA polymerase, is conserved in general…”
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    Journal Article
  2. 2

    Structures of an RNA polymerase promoter melting intermediate elucidate DNA unwinding by Boyaci, Hande, Chen, James, Jansen, Rolf, Darst, Seth A., Campbell, Elizabeth A.

    Published in Nature (London) (01-01-2019)
    “…A key regulated step of transcription is promoter melting by RNA polymerase (RNAP) to form the open promoter complex 1 – 3 . To generate the open complex, the…”
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    Journal Article
  3. 3

    Basis of narrow-spectrum activity of fidaxomicin on Clostridioides difficile by Cao, Xinyun, Boyaci, Hande, Chen, James, Bao, Yu, Landick, Robert, Campbell, Elizabeth A.

    Published in Nature (London) (21-04-2022)
    “…Fidaxomicin (Fdx) is widely used to treat Clostridioides difficile ( Cdiff ) infections, but the molecular basis of its narrow-spectrum activity in the human…”
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    Journal Article
  4. 4

    Fidaxomicin jams Mycobacterium tuberculosis RNA polymerase motions needed for initiation via RbpA contacts by Boyaci, Hande, Chen, James, Lilic, Mirjana, Palka, Margaret, Mooney, Rachel Anne, Landick, Robert, Darst, Seth A, Campbell, Elizabeth A

    Published in eLife (26-02-2018)
    “…Fidaxomicin (Fdx) is an antimicrobial RNA polymerase (RNAP) inhibitor highly effective against RNAP in vitro, but clinical use of Fdx is limited to treating…”
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    Journal Article
  5. 5
  6. 6

    Structure, Regulation, and Inhibition of the Quorum-Sensing Signal Integrator LuxO by Boyaci, Hande, Shah, Tayyab, Hurley, Amanda, Kokona, Bashkim, Li, Zhijie, Ventocilla, Christian, Jeffrey, Philip D, Semmelhack, Martin F, Fairman, Robert, Bassler, Bonnie L, Hughson, Frederick M

    Published in PLoS biology (24-05-2016)
    “…In a process called quorum sensing, bacteria communicate with chemical signal molecules called autoinducers to control collective behaviors. In pathogenic…”
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    Journal Article
  7. 7

    Engineering A Uranyl-Specific Binding Protein from NikR by Wegner, Seraphine V, Boyaci, Hande, Chen, Hao, Jensen, Mark P, He, Chuan

    Published in Angewandte Chemie (International ed.) (01-01-2009)
    “…A new pick-up line: The first uranyl-selective DNA-binding protein is designed using the E. coli nickel(II)-responsive protein NikR as the template. The…”
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    Journal Article
  8. 8
  9. 9

    Emissive Nucleosides as Molecular Rotors by Sinkeldam, Renatus W., Wheat, Andrea J., Boyaci, Hande, Tor, Yitzhak

    Published in Chemphyschem (25-02-2011)
    “…Sticky fingers: The emission intensity of modified pyrimidines containing an aryl moiety, linked by a single bond to the nucleobase in the 5‐position, show a…”
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    Journal Article
  10. 10

    Transcription initiation in mycobacteria: a biophysical perspective by Boyaci, Hande, Saecker, Ruth M., Campbell, Elizabeth A.

    Published in Transcription (14-03-2020)
    “…Recent biophysical studies of mycobacterial transcription have shed new light on this fundamental process in a group of bacteria that includes deadly pathogens…”
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    Journal Article
  11. 11

    Engineering A Uranyl‐Specific Binding Protein from NikR by Wegner, Seraphine V., Boyaci, Hande, Chen, Hao, Jensen, Mark P., He, Chuan

    Published in Angewandte Chemie (16-03-2009)
    “…Ein uranylselektives DNA bindendes Protein wurde ausgehend von dem Nickel(II)‐responsiven Protein NikR aus E. coli als Templat entwickelt. Das resultierende…”
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    Journal Article
  12. 12

    Structural and functional studies of the regulation and inhibition of LuxO, a AAA+ ATPase by Boyaci Selcuk, Hande

    Published 2017
    “…Quorum sensing is a widespread form of bacterial cell-cell communication that entails the production, release, and detection of small molecules called…”
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    Dissertation
  13. 13

    Engineering A Uranyl‐Specific Binding Protein from NikR by Wegner, Seraphine V., Boyaci, Hande, Chen, Hao, Jensen, Mark P., He, Chuan

    Published in Angewandte Chemie (16-03-2009)
    “…Ein uranylselektives DNA bindendes Protein wurde ausgehend von dem Nickel(II)‐responsiven Protein NikR aus E. coli als Templat entwickelt. Das resultierende…”
    Get full text
    Journal Article