Search Results - "Boxler, Martina I."

A novel bedtime pulsatile-release caffeine formula ameliorates sleep inertia symptoms immediately upon awakening by Dornbierer, Dario A., Yerlikaya, Firat, Wespi, Rafael, Boxler, Martina I., Voegel, Clarissa D., Schnider, Laura, Arslan, Aslihan, Baur, Diego M., Baumgartner, Markus R., Binz, Tina Maria, Kraemer, Thomas, Landolt, Hans-Peter

“…Sleep inertia is a disabling state of grogginess and impaired vigilance immediately upon awakening. The adenosine receptor antagonist, caffeine, is widely used…”
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Comparative Untargeted Metabolomics Analysis of the Psychostimulants 3,4-Methylenedioxy-Methamphetamine (MDMA), Amphetamine, and the Novel Psychoactive Substance Mephedrone after Controlled Drug Administration to Humans by Steuer, Andrea E., Kaelin, Daria, Boxler, Martina I., Eisenbeiss, Lisa, Holze, Friederike, Vizeli, Patrick, Czerwinska, Joanna, Dargan, Paul I., Abbate, Vincenzo, Liechti, Matthias E., Kraemer, Thomas

“…Psychoactive stimulants are a popular drug class which are used recreationally. Over the last decade, large numbers of new psychoactive substances (NPS) have…”
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Impact of three different peak picking software tools on the quality of untargeted metabolomics data by Wartmann, Yannick, Boxler, Martina I., Kraemer, Thomas, Steuer, Andrea E.

“…Data quality and control parameters are becoming more important in metabolomics. For peak picking, open-source or commercial solutions are used. Other…”
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Human Metabolome Changes after a Single Dose of 3,4-Methylenedioxymethamphetamine (MDMA) with Special Focus on Steroid Metabolism and Inflammation Processes by Boxler, Martina I, Streun, Gabriel L, Liechti, Matthias E, Schmid, Yasmin, Kraemer, Thomas, Steuer, Andrea E

“…The intake of 3,4-methylenedioxymethamphetamine (MDMA) is known to increase several endogenous substances involved in steroid and inflammation pathways…”
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Analytical considerations for (un)‐targeted metabolomic studies with special focus on forensic applications by Boxler, Martina I., Schneider, Tom D., Kraemer, Thomas, Steuer, Andrea E.

“…Over the past few years, the interest in metabolomics has increased in various fields including forensic toxicology. Forensic analysis typically requires a…”
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Inhibition potential of 3,4-methylenedioxymethamphetamine (MDMA) and its metabolites on the in vitro monoamine oxidase (MAO)-catalyzed deamination of the neurotransmitters serotonin and dopamine by Steuer, Andrea E., Boxler, Martina I., Stock, Lorena, Kraemer, Thomas

“…•First in vitro data on the inhibitory potential of MDMA and its metabolites on monoamine oxidase (MAO) in humans.•Only MDMA and MDA showed inhibition toward…”
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First Time View on Human Metabolome Changes after a Single Intake of 3,4-Methylenedioxymethamphetamine in Healthy Placebo-Controlled Subjects by Boxler, Martina I, Liechti, Matthias E, Schmid, Yasmin, Kraemer, Thomas, Steuer, Andrea E

“…3,4-Methylenedioxymethamphetamine (MDMA; "ecstasy") is widely consumed recreationally. Little is known about its effects on the human metabolome. Mapping…”
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Identification of new urinary gamma‐hydroxybutyric acid markers applying untargeted metabolomics analysis following placebo‐controlled administration to humans by Steuer, Andrea E., Raeber, Justine, Steuer, Christian, Boxler, Martina I., Dornbierer, Dario A., Bosch, Oliver G., Quednow, Boris B., Seifritz, Erich, Kraemer, Thomas

“…Gamma‐hydroxybutyrate (GHB) is a short‐chain fatty acid that occurs naturally in the mammalian brain and is prescribed as a medication against narcolepsy or…”
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Postmortem distribution and redistribution of MDAI and 2-MAPB in blood and alternative matrices by Staeheli, Sandra N., Boxler, Martina I., Oestreich, Andrea, Marti, Michelle, Gascho, Dominic, Bolliger, Stephan A., Kraemer, Thomas, Steuer, Andrea E.

“…•First case report involving MDAI and 2-MAPB.•Peripheral blood concentration was 38μg/L (MDAI) and 21μg/L (2-MAPB).•No significant postmortem concentration…”
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First Time View on Human Metabolome Changes after a Single Intake of 3,4-Methylene­dioxymethamphetamine in Healthy Placebo-Controlled Subjects by Boxler, Martina I, Liechti, Matthias E, Schmid, Yasmin, Kraemer, Thomas, Steuer, Andrea E

“…3,4-Methylene­dioxymethamphetamine (MDMA; “ecstasy”) is widely consumed recreationally. Little is known about its effects on the human metabolome. Mapping…”
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