Search Results - "Boxer, Lisa D"

A LncRNA-MAF:MAFB Transcription Factor Network Regulates Epidermal Differentiation by Lopez-Pajares, Vanessa, Qu, Kun, Zhang, Jiajing, Webster, Dan E., Barajas, Brook C., Siprashvili, Zurab, Zarnegar, Brian J., Boxer, Lisa D., Rios, Eon J., Tao, Shiying, Kretz, Markus, Khavari, Paul A.

“…Progenitor differentiation requires remodeling of genomic expression; however, in many tissues, such as epidermis, the spectrum of remodeled genes and the…”
Get full text

Early-Life Gene Expression in Neurons Modulates Lasting Epigenetic States by Stroud, Hume, Su, Susan C., Hrvatin, Sinisa, Greben, Alexander W., Renthal, William, Boxer, Lisa D., Nagy, M. Aurel, Hochbaum, Daniel R., Kinde, Benyam, Gabel, Harrison W., Greenberg, Michael E.

“…In mammals, the environment plays a critical role in promoting the final steps in neuronal development during the early postnatal period. While epigenetic…”
Get full text

Characterization of human mosaic Rett syndrome brain tissue by single-nucleus RNA sequencing by Renthal, William, Boxer, Lisa D., Hrvatin, Sinisa, Li, Emmy, Silberfeld, Andrew, Nagy, M. Aurel, Griffith, Eric C., Vierbuchen, Thomas, Greenberg, Michael E.

“…In females with X-linked genetic disorders, wild-type and mutant cells coexist within brain tissue because of X-chromosome inactivation, posing challenges for…”
Get full text

Lineage-specific dynamic and pre-established enhancer–promoter contacts cooperate in terminal differentiation by Rubin, Adam J, Barajas, Brook C, Furlan-Magaril, Mayra, Lopez-Pajares, Vanessa, Mumbach, Maxwell R, Howard, Imani, Kim, Daniel S, Boxer, Lisa D, Cairns, Jonathan, Spivakov, Mikhail, Wingett, Steven W, Shi, Minyi, Zhao, Zhixin, Greenleaf, William J, Kundaje, Anshul, Snyder, Michael, Chang, Howard Y, Fraser, Peter, Khavari, Paul A

“…Adam Rubin, Brook Barajas, Mayra Furlan-Magaril and colleagues studied dynamic chromatin across the genome of differentiating human skin keratinocytes,…”
Get full text

MeCP2 Represses the Rate of Transcriptional Initiation of Highly Methylated Long Genes by Boxer, Lisa D., Renthal, William, Greben, Alexander W., Whitwam, Tess, Silberfeld, Andrew, Stroud, Hume, Li, Emmy, Yang, Marty G., Kinde, Benyam, Griffith, Eric C., Bonev, Boyan, Greenberg, Michael E.

“…Mutations in the methyl-DNA-binding repressor protein MeCP2 cause the devastating neurodevelopmental disorder Rett syndrome. It has been challenging to…”
Get full text

ZNF750 Is a p63 Target Gene that Induces KLF4 to Drive Terminal Epidermal Differentiation by Sen, George L., Boxer, Lisa D., Webster, Dan E., Bussat, Rose T., Qu, Kun, Zarnegar, Brian J., Johnston, Danielle, Siprashvili, Zurab, Khavari, Paul A.

“…Disrupted epidermal differentiation characterizes numerous diseases that impact >25% of the population. In a search for dominant mediators of differentiation,…”
Get full text

HDAC inhibition results in widespread alteration of the histone acetylation landscape and BRD4 targeting to gene bodies by Slaughter, Mariesa J., Shanle, Erin K., Khan, Abid, Chua, Katrin F., Hong, Tao, Boxer, Lisa D., Allis, C. David, Josefowicz, Steven Z., Garcia, Benjamin A., Rothbart, Scott B., Strahl, Brian D., Davis, Ian J.

“…Histone acetylation levels are regulated by histone acetyltransferases (HATs) and histone deacetylases (HDACs) that antagonistically control the overall…”
Get full text

Network Analysis Identifies Mitochondrial Regulation of Epidermal Differentiation by MPZL3 and FDXR by Bhaduri, Aparna, Ungewickell, Alexander, Boxer, Lisa D., Lopez-Pajares, Vanessa, Zarnegar, Brian J., Khavari, Paul A.

“…Current gene expression network approaches commonly focus on transcription factors (TFs), biasing network-based discovery efforts away from potentially…”
Get full text

Cell cycle-dependent deacetylation of telomeric histone H3 lysine K56 by human SIRT6 by Michishita, Eriko, McCord, Ronald A., Boxer, Lisa D., Barber, Matthew F., Hong, Tao, Gozani, Or, Chua, Katrin F.

Get full text

ZNF750 interacts with KLF4 and RCOR1, KDM1A, and CTBP1/2 chromatin regulators to repress epidermal progenitor genes and induce differentiation genes by Boxer, Lisa D, Barajas, Brook, Tao, Shiying, Zhang, Jiajing, Khavari, Paul A

“…ZNF750 controls epithelial homeostasis by inhibiting progenitor genes while inducing differentiation genes, a role underscored by pathogenic ZNF750 mutations…”
Get full text

SIRT6 stabilizes DNA-dependent Protein Kinase at chromatin for DNA double-strand break repair by McCord, Ronald A., Michishita, Eriko, Hong, Tao, Berber, Elisabeth, Boxer, Lisa D., Kusumoto, Rika, Guan, Shenheng, Shi, Xiaobing, Gozani, Or, Burlingame, Alma L., Bohr, Vilhelm A., Chua, Katrin F.

Get full text

CALML5 is a ZNF750- and TINCR-induced protein that binds stratifin to regulate epidermal differentiation by Sun, Bryan K, Boxer, Lisa D, Ransohoff, Julia D, Siprashvili, Zurab, Qu, Kun, Lopez-Pajares, Vanessa, Hollmig, S Tyler, Khavari, Paul A

“…Outward migration of epidermal progenitors occurs with induction of hundreds of differentiation genes, but the identities of all regulators required for this…”
Get full text

Activity-induced MeCP2 phosphorylation regulates retinogeniculate synapse refinement by Tzeng, Christopher P, Whitwam, Tess, Boxer, Lisa D, Li, Emmy, Silberfeld, Andrew, Trowbridge, Sara, Mei, Kevin, Lin, Cindy, Shamah, Rebecca, Griffith, Eric C, Renthal, William, Chen, Chinfei, Greenberg, Michael E

“…Mutations in give rise to Rett syndrome (RTT), an X-linked neurodevelopmental disorder that results in broad cognitive impairments in females. While the exact…”
Get full text

SIRT6 stabilizes DNA-dependent protein kinase at chromatin for DNA double-strand break repair by McCord, Ronald A, Michishita, Eriko, Hong, Tao, Berber, Elisabeth, Boxer, Lisa D, Kusumoto, Rika, Guan, Shenheng, Shi, Xiaobing, Gozani, Or, Burlingame, Alma L, Bohr, Vilhelm A, Chua, Katrin F

“…The Sir2 chromatin regulatory factor links maintenance of genomic stability to life span extension in yeast. The mammalian Sir2 family member SIRT6 has been…”
Get full text

SIRT6 Links Histone H3 Lysine 9 Deacetylation to NF-κB-Dependent Gene Expression and Organismal Life Span by Kawahara, Tiara L.A., Michishita, Eriko, Adler, Adam S., Damian, Mara, Berber, Elisabeth, Lin, Meihong, McCord, Ron A., Ongaigui, Kristine C.L., Boxer, Lisa D., Chang, Howard Y., Chua, Katrin F.

“…Members of the sirtuin (SIRT) family of NAD-dependent deacetylases promote longevity in multiple organisms. Deficiency of mammalian SIRT6 leads to shortened…”
Get full text

SIRT6 links histone H3 lysine 9 deacetylation to control of NF-κB dependent gene expression and organismal lifespan by Kawahara, Tiara L.A., Michishita, Eriko, Adler, Adam S., Damian, Mara, Berber, Elisabeth, Lin, Meihong, McCord, Ron A., Ongaigui, Kristine C.L., Boxer, Lisa D., Chang, Howard Y., Chua, Katrin F.

“…Members of the Sirtuin (SIRT) family of NAD+-dependent deacetylases promote longevity in multiple organisms. Deficiency of mammalian SIRT6 leads to shortened…”
Get full text

SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaB-dependent gene expression and organismal life span by Kawahara, Tiara L A, Michishita, Eriko, Adler, Adam S, Damian, Mara, Berber, Elisabeth, Lin, Meihong, McCord, Ron A, Ongaigui, Kristine C L, Boxer, Lisa D, Chang, Howard Y, Chua, Katrin F

“…Members of the sirtuin (SIRT) family of NAD-dependent deacetylases promote longevity in multiple organisms. Deficiency of mammalian SIRT6 leads to shortened…”
Get full text