Search Results - "Bowzard, John"
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1
NLRX1 Protein Attenuates Inflammatory Responses to Infection by Interfering with the RIG-I-MAVS and TRAF6-NF-κB Signaling Pathways
Published in Immunity (Cambridge, Mass.) (24-06-2011)“…The nucleotide-binding domain and leucine-rich-repeat-containing (NLR) proteins regulate innate immunity. Although the positive regulatory impact of NLRs is…”
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Journal Article -
2
Performance of the Trioplex real-time RT-PCR assay for detection of Zika, dengue, and chikungunya viruses
Published in Nature communications (11-04-2018)“…The emergence and spread of Zika virus (ZIKV) presented a challenge to the diagnosis of ZIKV infections in areas with transmission of dengue (DENV) and…”
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Journal Article -
3
Influenza A viral nucleoprotein interacts with cytoskeleton scaffolding protein α‐actinin‐4 for viral replication
Published in The FEBS journal (01-07-2014)“…Influenza A virus (IAV), similar to other viruses, exploits the machinery of human host cells for its survival and replication. We identified α‐actinin‐4, a…”
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Journal Article -
4
5'PPP-RNA induced RIG-I activation inhibits drug-resistant avian H5N1 as well as 1918 and 2009 pandemic influenza virus replication
Published in Virology journal (21-05-2010)“…Emergence of drug-resistant strains of influenza viruses, including avian H5N1 with pandemic potential, 1918 and 2009 A/H1N1 pandemic viruses to currently used…”
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Journal Article -
5
Increased MDSC accumulation and Th2 biased response to influenza A virus infection in the absence of TLR7 in mice
Published in PloS one (23-09-2011)“…Toll-like receptors (TLRs) play an important role in the induction of innate and adaptive immune response against influenza A virus (IAV) infection; however,…”
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Journal Article -
6
Influenza A viral nucleoprotein interacts with cytoskeleton scaffolding protein [alpha]-actinin-4 for viral replication
Published in The FEBS journal (01-07-2014)“…Influenza A virus (IAV), similar to other viruses, exploits the machinery of human host cells for its survival and replication. We identified…”
Get full text
Journal Article -
7
NLRX1 protein attenuates inflammatory responses to virus infection by interfering with the RIG-I-MAVS signaling pathway and TRAF6 ubiquitin ligase
Published in Immunity (Cambridge, Mass.) (24-06-2011)“…The nucleotide-binding domain and leucine-rich repeat containing (NLR) proteins regulate innate immunity. Although the positive regulatory impact of NLRs is…”
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Journal Article -
8
Molecular interactions of the retroviral Gag protein during assembly and infection
Published 01-01-1999“…All retroviruses contain three genes that encode the Gag, Pol, and Env polyproteins. Each of these precursors is in turn cleaved to form the multiple protein…”
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Dissertation