Search Results - "Bowyer, Paul"

Tackling the emerging threat of antifungal resistance to human health by Fisher, Matthew C., Alastruey-Izquierdo, Ana, Berman, Judith, Bicanic, Tihana, Bignell, Elaine M., Bowyer, Paul, Bromley, Michael, Brüggemann, Roger, Garber, Gary, Cornely, Oliver A., Gurr, Sarah. J., Harrison, Thomas S., Kuijper, Ed, Rhodes, Johanna, Sheppard, Donald C., Warris, Adilia, White, P. Lewis, Xu, Jianping, Zwaan, Bas, Verweij, Paul E.

“…Invasive fungal infections pose an important threat to public health and are an under-recognized component of antimicrobial resistance, an emerging crisis…”
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Proteomic analysis of fractionated Toxoplasma oocysts reveals clues to their environmental resistance by Fritz, Heather M, Bowyer, Paul W, Bogyo, Matthew, Conrad, Patricia A, Boothroyd, John C

“…Toxoplasma gondii is an obligate intracellular parasite that is unique in its ability to infect a broad range of birds and mammals, including humans, leading…”
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On the lineage of Aspergillus fumigatus isolates in common laboratory use by Bertuzzi, Margherita, van Rhijn, Norman, Krappmann, Sven, Bowyer, Paul, Bromley, Michael J, Bignell, Elaine M

“…Abstract The origin of isolates routinely used by the community of Aspergillus fumigatus researchers is periodically a matter of intense discussion at our…”
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Telomere-to-telomere genome sequence of the model mould pathogen Aspergillus fumigatus by Bowyer, Paul, Currin, Andrew, Delneri, Daniela, Fraczek, Marcin G.

“…The pathogenic fungus Aspergillus fumigatus is a major etiological agent of fungal invasive and chronic diseases affecting tens of millions of individuals…”
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Heterotypic interactions drive antibody synergy against a malaria vaccine candidate by Ragotte, Robert J., Pulido, David, Lias, Amelia M., Quinkert, Doris, Alanine, Daniel G. W., Jamwal, Abhishek, Davies, Hannah, Nacer, Adéla, Lowe, Edward D., Grime, Geoffrey W., Illingworth, Joseph J., Donat, Robert F., Garman, Elspeth F., Bowyer, Paul W., Higgins, Matthew K., Draper, Simon J.

“…Understanding mechanisms of antibody synergy is important for vaccine design and antibody cocktail development. Examples of synergy between antibodies are…”
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Development of a novel mycobiome diagnostic for fungal infection by Weaver, Danielle, Novak-Frazer, Lilyann, Palmer, Maisie, Richardson, Malcolm, Bromley, Mike, Bowyer, Paul

“…Amplicon-based mycobiome analysis has the potential to identify all fungal species within a sample and hence could provide a valuable diagnostic assay for use…”
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The negative cofactor 2 complex is a key regulator of drug resistance in Aspergillus fumigatus by Furukawa, Takanori, van Rhijn, Norman, Fraczek, Marcin, Gsaller, Fabio, Davies, Emma, Carr, Paul, Gago, Sara, Fortune-Grant, Rachael, Rahman, Sayema, Gilsenan, Jane Mabey, Houlder, Emma, Kowalski, Caitlin H., Raj, Shriya, Paul, Sanjoy, Cook, Peter, Parker, Josie E., Kelly, Steve, Cramer, Robert A., Latgé, Jean-Paul, Moye-Rowley, Scott, Bignell, Elaine, Bowyer, Paul, Bromley, Michael J.

“…The frequency of antifungal resistance, particularly to the azole class of ergosterol biosynthetic inhibitors, is a growing global health problem. Survival…”
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Sterol Biosynthesis and Azole Tolerance Is Governed by the Opposing Actions of SrbA and the CCAAT Binding Complex by Gsaller, Fabio, Hortschansky, Peter, Furukawa, Takanori, Carr, Paul D, Rash, Bharat, Capilla, Javier, Müller, Christoph, Bracher, Franz, Bowyer, Paul, Haas, Hubertus, Brakhage, Axel A, Bromley, Michael J

“…Azole drugs selectively target fungal sterol biosynthesis and are critical to our antifungal therapeutic arsenal. However, resistance to this class of drugs,…”
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Strain dependent variation of immune responses to A. fumigatus: definition of pathogenic species by Rizzetto, Lisa, Giovannini, Gloria, Bromley, Michael, Bowyer, Paul, Romani, Luigina, Cavalieri, Duccio

“…For over a century microbiologists and immunologist have categorized microorganisms as pathogenic or non-pathogenic species or genera. This definition, clearly…”
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Pathogenicity and virulence of Aspergillus fumigatus by Earle, Kayleigh, Valero, Clara, Conn, Daniel P., Vere, George, Cook, Peter C., Bromley, Michael J., Bowyer, Paul, Gago, Sara

“…Pulmonary infections caused by the mould pathogen Aspergillus fumigatus are a major cause of morbidity and mortality globally. Compromised lung defences…”
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The one health problem of azole resistance in Aspergillus fumigatus: current insights and future research agenda by Verweij, Paul E., Lucas, John A., Arendrup, Maiken C., Bowyer, Paul, Brinkmann, Arjen J.F., Denning, David W., Dyer, Paul S., Fisher, Matthew C., Geenen, Petra L., Gisi, Ulrich, Hermann, Dietrich, Hoogendijk, Andre, Kiers, Eric, Lagrou, Katrien, Melchers, Willem J.G., Rhodes, Johanna, Rietveld, Anton G., Schoustra, Sijmen E., Stenzel, Klaus, Zwaan, Bas J., Fraaije, Bart A.

“…Azole resistance is a concern for the management of diseases caused by Aspergillus fumigatus in humans. Azole fungicide use in the environment has been…”
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Linking calcium signaling and mitochondrial function in fungal drug resistance by Bowyer, Paul, Bromley, Michael J., Denning, David W.

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The Proinflammatory Cytokine IL-36γ Is a Global Discriminator of Harmless Microbes and Invasive Pathogens within Epithelial Tissues by Macleod, Thomas, Ainscough, Joseph S., Hesse, Christina, Konzok, Sebastian, Braun, Armin, Buhl, Anna-Lena, Wenzel, Joerg, Bowyer, Paul, Terao, Yutaka, Herrick, Sarah, Wittmann, Miriam, Stacey, Martin

“…Epithelial tissues represent vital interfaces between organisms and their environment. As they are constantly exposed to harmful pathogens, innocuous…”
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Cryptic Species and Azole Resistance in the Aspergillus niger Complex by HOWARD, Susan J, HARRISON, Elizabeth, BOWYER, Paul, VARGA, Janos, DENNING, David W

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Phagolysosomal Survival Enables Non-lytic Hyphal Escape and Ramification Through Lung Epithelium During Aspergillus fumigatus Infection by Seidel, Constanze, Moreno-Velásquez, Sergio D, Ben-Ghazzi, Nagwa, Gago, Sara, Read, Nick D, Bowyer, Paul

“…is the most important mould pathogen in immunosuppressed patients. Suboptimal clearance of inhaled spores results in the colonisation of the lung airways by…”
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Expanding the Malaria Antibody Toolkit: Development and Characterisation of Plasmodium falciparum RH5, CyRPA, and CSP Recombinant Human Monoclonal Antibodies by Nacer, Adéla, Kivi, Gaily, Pert, Raini, Juronen, Erkki, Holenya, Pavlo, Aliprandini, Eduardo, Amino, Rogerio, Silvie, Olivier, Quinkert, Doris, Le Duff, Yann, Hurley, Matthew, Reimer, Ulf, Tover, Andres, Draper, Simon J, Gilbert, Sarah, Ho, Mei Mei, Bowyer, Paul W

“…Malaria, an infection caused by apicomplexan parasites of the genus , continues to exact a significant toll on public health with over 200 million cases…”
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Optimization of incubation conditions of Plasmodium falciparum antibody multiplex assays to measure IgG, IgG1–4, IgM and IgE using standard and customized reference pools for sero-epidemiological and vaccine studies by Ubillos, Itziar, Jimnnez, Alfons, Vidal, Marta, Bowyer, Paul W, Gaur, Deepak, Dutta, Sheetij, Gamain, Benoit, Coppel, Ross, Chauhan, Virander, Lanar, David, Chitnis, Chetan, Angov, Evelina, Beeson, James, Cavanagh, David, Campo, Joseph J, Aguilar, Ruth, Dobaeo, Carlota

“…Background The quantitative suspension array technology (qSAT) is a useful platform for malaria immune marker discovery. However, a major challenge for large…”
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Lung colonization by Aspergillus fumigatus is controlled by ZNF77 by Gago, Sara, Overton, Nicola L. D., Ben-Ghazzi, Nagwa, Novak-Frazer, Lilyann, Read, Nick D., Denning, David W., Bowyer, Paul

“…Aspergillus fumigatus is a critical pathogen of humans. Exposure to A. fumigatus conidia occurs frequently but is normally cleared from the respiratory…”
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Bradyzoite Pseudokinase 1 Is Crucial for Efficient Oral Infectivity of the Toxoplasma gondii Tissue Cyst by Buchholz, Kerry R, Bowyer, Paul W, Boothroyd, John C

“…Classifications Services EC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Criteria for effective site selection of direct air capture and storage projects by Harzendorf, Freia, Markus, Till, Ross, Andrew, Valencia Cotera, Rodrigo, Baust, Constanze, Vögele, Stefan, Taraborrelli, Domenico, Zapp, Petra, Karydis, Vlassis A, Bowyer, Paul, Stolten, Detlef

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