Search Results - "Bowman, W P"
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Long-term follow-up of imatinib in pediatric Philadelphia chromosome-positive acute lymphoblastic leukemia: Children's Oncology Group Study AALL0031
Published in Leukemia (01-07-2014)“…We previously reported preliminary findings that post induction imatinib mesylate (340 mg/m 2 /day), in combination with intensive chemotherapy, resulted in…”
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Clinical utility and implications of asparaginase antibodies in acute lymphoblastic leukemia
Published in Leukemia (01-11-2012)“…Hypersensitivity to asparaginase is common, but the differential diagnosis can be challenging and the diagnostic utility of antibody tests is unclear. We…”
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Genome-wide Interrogation of Germline Genetic Variation Associated With Treatment Response in Childhood Acute Lymphoblastic Leukemia
Published in JAMA : the journal of the American Medical Association (28-01-2009)“…CONTEXT Pediatric acute lymphoblastic leukemia (ALL) is the prototype for a drug-responsive malignancy. Although cure rates exceed 80%, considerable…”
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A revised definition for cure of childhood acute lymphoblastic leukemia
Published in Leukemia (01-12-2014)“…With improved contemporary therapy, we reassess long-term outcome in patients completing treatment for childhood acute lymphoblastic leukemia (ALL) to…”
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ETV6-RUNX1-positive childhood acute lymphoblastic leukemia: improved outcome with contemporary therapy
Published in Leukemia (01-02-2012)“…ETV6-RUNX1 fusion is the most common genetic aberration in childhood acute lymphoblastic leukemia (ALL). To evaluate whether outcomes for this drug-sensitive…”
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Clinical impact of minimal residual disease in children with different subtypes of acute lymphoblastic leukemia treated with Response-Adapted therapy
Published in Leukemia (01-02-2017)“…To determine the clinical significance of minimal residual disease (MRD) in patients with prognostically relevant subtypes of childhood acute lymphoblastic…”
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Improved survival for children with B-cell acute lymphoblastic leukemia and stage IV small noncleaved-cell lymphoma: a pediatric oncology group study
Published in Journal of clinical oncology (01-04-1996)“…In an effort to improve outcome for children with advanced B-cell malignancies, a treatment plan based on a published regimen that consists of four courses of…”
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Secondary acute myeloid leukemia in children with acute lymphoblastic leukemia treated with etoposide
Published in Journal of clinical oncology (01-02-1993)“…To describe the occurrence of secondary acute myeloid leukemia (AML) in children with acute lymphoblastic leukemia (ALL) treated with etoposide (VP-16). Two…”
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Serum aminotransferase elevation during and following treatment of childhood acute lymphoblastic leukemia
Published in Journal of clinical oncology (01-04-1997)“…The clinical significance of methotrexate (MTX)-induced hepatic toxicity in children with acute lymphoblastic leukemia (ALL) is poorly defined. Therefore, we…”
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Brexit: The influence of motivation to respond without prejudice, willingness to disagree, and attitudes to immigration
Published in British journal of social psychology (01-01-2021)“…Britain’s unexpected vote to leave the European Union (Brexit) in June 2016 has proved divisive and damaging both within the United Kingdom and…”
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Intensive oral methotrexate protects against lymphoid marrow relapse in childhood B-precursor acute lymphoblastic leukemia
Published in Journal of clinical oncology (01-10-1996)“…To describe the use of combination chemotherapy, including divided-dose oral methotrexate (dMTX), for children with B-precursor acute lymphoblastic leukemia…”
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Universal Inactivation of Both p16 and p15 but not Downstream Components Is an Essential Event in the Pathogenesis of T-Cell Acute Lymphoblastic Leukemia
Published in Clinical cancer research (01-04-2000)“…p16/p15 regulate the cell cycle pathway by inhibiting the cyclin Ds-CDK4/6 mediated phosphorylation of pRb. We reported previously that in T-cell acute…”
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Therapeutic trial for infant acute lymphoblastic leukemia : The Pediatric Oncology Group experience (POG 8493)
Published in Journal of pediatric hematology/oncology (1997)“…Despite improved event-free survival of older children with acute lymphocytic leukemia (ALL), infants <1 year of age continue to have a very poor prognosis. A…”
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Unexpected acute neurologic toxicity in the treatment of children with acute lymphoblastic leukemia
Published in JNCI : Journal of the National Cancer Institute (19-02-1992)“…Our current protocol for treatment of childhood acute lymphoblastic leukemia (ALL) was designed to assess the efficacy of methotrexate (MTX) plus…”
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Results of treatment of advanced-stage Burkitt's lymphoma and B cell (SIg+) acute lymphoblastic leukemia with high-dose fractionated cyclophosphamide and coordinated high-dose methotrexate and cytarabine
Published in Journal of clinical oncology (01-12-1986)“…To address the problem of historically poor results in the treatment of children with advanced-stage Burkitt's lymphoma and B cell (SIg+) acute lymphoblastic…”
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Prognostic Importance of Blast Cell DNA Content in Childhood Acute Lymphoblastic Leukemia
Published in Blood (01-05-1985)“…Using flow cytometric techniques, we determined the pretreatment distribution of DNA content in propidium iodide-stained leukemic blasts from 205 children with…”
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Treatment of children with epipodophyllotoxin‐induced secondary acute myeloid leukemia
Published in Cancer (01-03-1997)“…BACKGROUND Secondary acute myeloid leukemia (AML) after treatment with epipodophyllotoxins is being observed with increased frequency. Therapeutic options are…”
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Clinical pharmacodynamics of high-dose methotrexate in acute lymphocytic leukemia. Identification of a relation between concentration and effect
Published in The New England journal of medicine (20-02-1986)“…High-dose methotrexate (500 to 33,600 mg per square meter of body-surface area) with leucovorin rescue is a common component of therapy for acute lymphocytic…”
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Prime and prejudice: Brief stereotypical media representations can increase prejudicial attitudes and behaviour towards people with schizophrenia
Published in Journal of community & applied social psychology (01-05-2019)“…Prejudice against people with mental illnesses remains a significant problem in the United Kingdom and in many other countries despite sustained efforts by…”
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