Search Results - "Bowman, Marianne E"

Evolution of the chalcone-isomerase fold from fatty-acid binding to stereospecific catalysis by Ngaki, Micheline N., Louie, Gordon V., Philippe, Ryan N., Manning, Gerard, Pojer, Florence, Bowman, Marianne E., Li, Ling, Larsen, Elise, Wurtele, Eve Syrkin, Noel, Joseph P.

“…The diffusion limited stereospecific enzyme chalcone isomerase represents the adaptive evolution of a catalytically perfected enzyme from non-catalytic,…”
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Rapid Synthesis of Auxin via a New Tryptophan-Dependent Pathway Is Required for Shade Avoidance in Plants by Tao, Yi, Ferrer, Jean-Luc, Ljung, Karin, Pojer, Florence, Hong, Fangxin, Long, Jeff A., Li, Lin, Moreno, Javier E., Bowman, Marianne E., Ivans, Lauren J., Cheng, Youfa, Lim, Jason, Zhao, Yunde, Ballaré, Carlos L., Sandberg, Göran, Noel, Joseph P., Chory, Joanne

“…Plants grown at high densities perceive a decrease in the red to far-red (R:FR) ratio of incoming light, resulting from absorption of red light by canopy…”
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Overcoming resolution attenuation during tilted cryo-EM data collection by Aiyer, Sriram, Baldwin, Philip R., Tan, Shi Min, Shan, Zelin, Oh, Juntaek, Mehrani, Atousa, Bowman, Marianne E., Louie, Gordon, Passos, Dario Oliveira, Đorđević-Marquardt, Selena, Mietzsch, Mario, Hull, Joshua A., Hoshika, Shuichi, Barad, Benjamin A., Grotjahn, Danielle A., McKenna, Robert, Agbandje-McKenna, Mavis, Benner, Steven A., Noel, Joseph A. P., Wang, Dong, Tan, Yong Zi, Lyumkis, Dmitry

“…Structural biology efforts using cryogenic electron microscopy are frequently stifled by specimens adopting “preferred orientations” on grids, leading to…”
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Structure-Function-Folding Relationship in a WW Domain by Jäger, Marcus, Zhang, Yan, Bieschke, Jan, Nguyen, Houbi, Dendle, Maria, Bowman, Marianne E., Noel, Joseph P., Gruebele, Martin, Kelly, Jeffery W.

“…Protein folding barriers result from a combination of factors including unavoidable energetic frustration from nonnative interactions, natural variation and…”
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Bifunctional Substrate Activation via an Arginine Residue Drives Catalysis in Chalcone Isomerases by Burke, Jason R, La Clair, James J, Philippe, Ryan N, Pabis, Anna, Corbella, Marina, Jez, Joseph M, Cortina, George A, Kaltenbach, Miriam, Bowman, Marianne E, Louie, Gordon V, Woods, Katherine B, Nelson, Andrew T, Tawfik, Dan S, Kamerlin, Shina C.L, Noel, Joseph P

“…Chalcone isomerases are plant enzymes that perform enantioselective oxa-Michael cyclizations of 2′-hydroxychalcones into flavanones. An X-ray crystal structure…”
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Structural and Kinetic Analysis of Prolyl-isomerization/Phosphorylation Cross-Talk in the CTD Code by Zhang, Mengmeng, Wang, Xiaodong J, Chen, Xi, Bowman, Marianne E, Luo, Yonghua, Noel, Joseph P, Ellington, Andrew D, Etzkorn, Felicia A, Zhang, Yan

“…The C-terminal domain (CTD) of eukaryotic RNA polymerase II is an essential regulator for RNA polymerase II-mediated transcription. It is composed of multiple…”
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Conformational Flexibility Underlies Ubiquitin Ligation Mediated by the WWP1 HECT Domain E3 Ligase by Verdecia, Mark A, Joazeiro, Claudio A.P, Wells, Nicholas J, Ferrer, Jean-Luc, Bowman, Marianne E, Hunter, Tony, Noel, Joseph P

“…Ubiquitin ligases (E3) select proteins for ubiquitylation, a modification that directs altered subcellular trafficking and/or degradation of the target…”
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Structural basis for phosphoserine-proline recognition by group IV WW domains by Noel, Joseph P, Verdecia, Mark A, Bowman, Marianne E, Lu, Kun Ping, Hunter, Tony

“…Pin1 contains an N-terminal WW domain and a C-terminal peptidyl-prolyl cis-trans isomerase (PPIase) domain connected by a flexible linker. To address the…”
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multiple phenylpropene synthases in both Clarkia breweri and Petunia hybrida represent two distinct protein lineages by Koeduka, Takao, Louie, Gordon V, Orlova, Irina, Kish, Christine M, Ibdah, Mwafaq, Wilkerson, Curtis G, Bowman, Marianne E, Baiga, Thomas J, Noel, Joseph P, Dudareva, Natalia, Pichersky, Eran

“…Many plants synthesize the volatile phenylpropene compounds eugenol and isoeugenol to serve in defense against herbivores and pathogens and to attract…”
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Biosynthesis of Dictyostelium discoideum differentiation-inducing factor by a hybrid type I fatty acid-type III polyketide synthase by Kay, Robert R, Noel, Joseph P, Austin, Michael B, Saito, Tamao, Bowman, Marianne E, Haydock, Stephen, Kato, Atsushi, Moore, Bradley S

“…Differentiation-inducing factors (DIFs) are well known to modulate formation of distinct communal cell types from identical Dictyostelium discoideum amoebas,…”
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Structural Basis for High-Affinity Peptide Inhibition of Human Pin1 by Zhang, Yan, Daum, Sebastian, Wildemann, Dirk, Zhou, Xiao Zhen, Verdecia, Mark A, Bowman, Marianne E, Lücke, Christian, Hunter, Tony, Lu, Kun-Ping, Fischer, Gunter, Noel, Joseph P

“…Human Pin1 is a key regulator of cell-cycle progression and plays growth-promoting roles in human cancers. High-affinity inhibitors of Pin1 may provide a…”
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Structure and mechanism of the evolutionarily unique plant enzyme chalcone isomerase by Noel, Joseph P, Jez, Joseph M, Bowman, Marianne E, Dixon, Richard A

“…Chalcone isomerase (CHI) catalyzes the intramolecular cyclization of chalcone synthesized by chalcone synthase (CHS) into (2S)-naringenin, an essential…”
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Crystal Structure of a Bacterial Type III Polyketide Synthase and Enzymatic Control of Reactive Polyketide Intermediates by Austin, Michael B, Izumikawa, Miho, Bowman, Marianne E, Udwary, Daniel W, Ferrer, Jean-Luc, Moore, Bradley S, Noel, Joseph P

“…In bacteria, a structurally simple type III polyketide synthase (PKS) known as 1,3,6,8-tetrahydroxynaphthlene synthase (THNS) catalyzes the iterative…”
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Expanding the Biosynthetic Repertoire of Plant Type III Polyketide Synthases by Altering Starter Molecule Specificity by Jez, Joseph M., Bowman, Marianne E., Noel, Joseph P.

“…Type III polyketide synthases (PKS) generate an array of natural products by condensing multiple acetyl units derived from malonyl-CoA to thioester-linked…”
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Structural Elucidation of Chalcone Reductase and Implications for Deoxychalcone Biosynthesis by Bomati, Erin K., Austin, Michael B., Bowman, Marianne E., Dixon, Richard A., Noel, Joseph P.

“…4,2′,4′,6′-tetrahydroxychalcone (chalcone) and 4,2′,4′-trihydroxychalcone (deoxychalcone) serve as precursors of ecologically important flavonoids and…”
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Dissection of Malonyl-Coenzyme A Decarboxylation from Polyketide Formation in the Reaction Mechanism of a Plant Polyketide Synthase by Jez, Joseph M, Ferrer, Jean-Luc, Bowman, Marianne E, Dixon, Richard A, Noel, Joseph P

“…Chalcone synthase (CHS) catalyzes formation of the phenylpropanoid chalcone from one p-coumaroyl-CoA and three malonyl-coenzyme A (CoA) thioesters. The…”
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Structure and reaction mechanism of basil eugenol synthase by Louie, Gordon V, Baiga, Thomas J, Bowman, Marianne E, Koeduka, Takao, Taylor, John H, Spassova, Snejina M, Pichersky, Eran, Noel, Joseph P

“…Phenylpropenes, a large group of plant volatile compounds that serve in multiple roles in defense and pollinator attraction, contain a propenyl side chain…”
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Modulation of auxin formation by the cytosolic phenylalanine biosynthetic pathway by Lynch, Joseph H., Qian, Yichun, Guo, Longyun, Maoz, Itay, Huang, Xing-Qi, Garcia, Alekzander S., Louie, Gordon, Bowman, Marianne E., Noel, Joseph P., Morgan, John A., Dudareva, Natalia

“…In plants, phenylalanine biosynthesis occurs via two compartmentally separated pathways. Overexpression of petunia chorismate mutase 2 ( PhCM2 ), which…”
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Structure-Guided Programming of Polyketide Chain-Length Determination in Chalcone Synthase by Jez, Joseph M, Bowman, Marianne E, Noel, Joseph P

“…Chalcone synthase (CHS) belongs to the family of type III polyketide synthases (PKS) that catalyze formation of structurally diverse polyketides. CHS…”
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Functional Analyses of Caffeic Acid O-Methyltransferase and Cinnamoyl-CoA-Reductase Genes from Perennial Ryegrass (Lolium perenne) by Tu, Yi, Rochfort, Simone, Liu, Zhiqian, Ran, Yidong, Griffith, Megan, Badenhorst, Pieter, Louie, Gordon V, Bowman, Marianne E, Smith, Kevin F, Noel, Joseph P, Mouradov, Aidyn, Spangenberg, German

“…Cinnamoyl CoA-reductase (CCR) and caffeic acid O-methyltransferase (COMT) catalyze key steps in the biosynthesis of monolignols, which serve as building blocks…”
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