Search Results - "Bowman, Lesley A H"

Peroxynitrite stress is exacerbated by flavohaemoglobin-derived oxidative stress in Salmonella Typhimurium and is relieved by nitric oxide by MCLEAN, Samantha, BOWMAN, Lesley A. H, POOLE, Robert K

“…Oxidative and nitrosative stresses including nitric oxide (NO), superoxide (O2⁻) and peroxynitrite play key roles in determining the outcome of bacterial…”
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Characterisation of ShigellaSpa33 and ThermotogaFliM/N reveals a new model for C-ring assembly in T3SS by McDowell, Melanie A, Marcoux, Julien, McVicker, Gareth, Johnson, Steven, Fong, Yu Hang, Stevens, Rebecca, Bowman, Lesley A H, Degiacomi, Matteo T, Yan, Jun, Wise, Adam, Friede, Miriam E, Benesch, Justin L P, Deane, Janet E, Tang, Christoph M, Robinson, Carol V, Lea, Susan M

“…Summary Flagellar type III secretion systems (T3SS) contain an essential cytoplasmic-ring (C-ring) largely composed of two proteins FliM and FliN, whereas an…”
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Human oxygen sensing may have origins in prokaryotic elongation factor Tu prolyl-hydroxylation by Scotti, John S., Leung, Ivanhoe K. H., Ge, Wei, Bentley, Michael A., Paps, Jordi, Kramer, Holger B., Lee, Joongoo, Aik, WeiShen, Choi, Hwanho, Paulsen, Steinar M., Bowman, Lesley A. H., Loik, Nikita D., Horita, Shoichiro, Ho, Chia-hua, Kershaw, Nadia J., Tang, Christoph M., Claridge, Timothy D. W., Preston, Gail M., McDonough, Michael A., Schofield, Christopher J.

“…Significance The Fe(II)- and 2-oxoglutarate (2OG)-dependent hypoxia-inducible transcription factor prolyl-hydroxylases play a central role in human oxygen…”
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Peroxynitrite Toxicity in Escherichia coli K12 Elicits Expression of Oxidative Stress Responses and Protein Nitration and Nitrosylation by McLean, Samantha, Bowman, Lesley A.H., Sanguinetti, Guido, Read, Robert C., Poole, Robert K.

“…Peroxynitrite is formed in macrophages by the diffusion-limited reaction of superoxide and nitric oxide. This highly reactive species is thought to contribute…”
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KatG from Salmonella Typhimurium is a peroxynitritase by McLean, Samantha, Bowman, Lesley A.H., Poole, Robert K.

“…Pathogenic bacteria elicit protective responses to oxidative and nitrosative stresses. Although such responses are generally distinct, it was recently reported…”
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Modular capsid decoration boosts adenovirus vaccine-induced humoral immunity against SARS-CoV-2 by Dicks, Matthew D.J., Rose, Louisa M., Russell, Rebecca A., Bowman, Lesley A.H., Graham, Carl, Jimenez-Guardeño, Jose M., Doores, Katie J., Malim, Michael H., Draper, Simon J., Howarth, Mark, Biswas, Sumi

“…Adenovirus vector vaccines have been widely and successfully deployed in response to coronavirus disease 2019 (COVID-19). However, despite inducing potent…”
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The diversity of microbial responses to nitric oxide and agents of nitrosative stress close cousins but not identical twins by Bowman, Lesley A H, McLean, Samantha, Poole, Robert K, Fukuto, Jon M

“…Nitric oxide and related nitrogen species (reactive nitrogen species) now occupy a central position in contemporary medicine, physiology, biochemistry, and…”
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Nitrosothiols in bacterial pathogens and pathogenesis by Laver, Jay R, McLean, Samantha, Bowman, Lesley A H, Harrison, Laura J, Read, Robert C, Poole, Robert K

“…The formation and degradation of S-nitrosothiols (SNOs) are important mechanisms of post-translational protein modification and appear to be ubiquitous in…”
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Characterisation of Shigella Spa33 and Thermotoga FliM/N reveals a new model for C‐ring assembly in T3SS by McDowell, Melanie A., Marcoux, Julien, McVicker, Gareth, Johnson, Steven, Fong, Yu Hang, Stevens, Rebecca, Bowman, Lesley A. H., Degiacomi, Matteo T., Yan, Jun, Wise, Adam, Friede, Miriam E., Benesch, Justin L. P., Deane, Janet E., Tang, Christoph M., Robinson, Carol V., Lea, Susan M.

“…Summary Flagellar type III secretion systems (T3SS) contain an essential cytoplasmic‐ring (C‐ring) largely composed of two proteins FliM and FliN, whereas an…”
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Ligand uptake in Mycobacterium tuberculosis truncated hemoglobins is controlled by both internal tunnels and active site water molecules by Boron, Ignacio, Bustamante, Juan Pablo, Davidge, Kelly S, Singh, Sandip, Bowman, Lesley AH, Tinajero-Trejo, Mariana, Carballal, Sebastián, Radi, Rafael, Poole, Robert K, Dikshit, Kanak, Estrin, Dario A, Marti, Marcelo A, Boechi, Leonardo

“…Mycobacterium tuberculosis, the causative agent of human tuberculosis, has two proteins belonging to the truncated hemoglobin (trHb) family. Mt-trHbN presents…”
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Ligand uptake in Mycobacterium tuberculosis truncated hemoglobins is controlled by both internal tunnels and active site water molecules [version 1; peer review: 1 approved, 1 approved with reservations] by Boron, Ignacio, Bustamante, Juan Pablo, Davidge, Kelly S, Singh, Sandip, Bowman, Lesley AH, Tinajero-Trejo, Mariana, Carballal, Sebastián, Radi, Rafael, Poole, Robert K, Dikshit, Kanak, Estrin, Dario A, Marti, Marcelo A, Boechi, Leonardo

“…Mycobacterium tuberculosis, the causative agent of human tuberculosis, has two proteins belonging to the truncated hemoglobin (trHb) family. Mt-trHbN presents…”
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