Search Results - "Bowman, Caitlyn E"

Developmental regulation and localization of carnitine palmitoyltransferases (CPTs) in rat brain by Jernberg, Jennifer N., Bowman, Caitlyn E., Wolfgang, Michael J., Scafidi, Susanna

“…While the brain's high energy demands are largely met by glucose, brain is also equipped with the ability to oxidize fatty acids for energy and metabolism. The…”
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Preventing Allograft Rejection by Targeting Immune Metabolism by Lee, Chen-Fang, Lo, Ying-Chun, Cheng, Chih-Hsien, Furtmüller, Georg J., Oh, Byoungchol, Andrade-Oliveira, Vinicius, Thomas, Ajit G., Bowman, Caitlyn E., Slusher, Barbara S., Wolfgang, Michael J., Brandacher, Gerald, Powell, Jonathan D.

“…Upon antigen recognition and co-stimulation, T lymphocytes upregulate the metabolic machinery necessary to proliferate and sustain effector function. This…”
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Metabolic and tissue-specific regulation of acyl-CoA metabolism by Ellis, Jessica M, Bowman, Caitlyn E, Wolfgang, Michael J

“…Acyl-CoA formation initiates cellular fatty acid metabolism. Acyl-CoAs are generated by the ligation of a fatty acid to Coenzyme A mediated by a large family…”
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Maternal Lipid Metabolism Directs Fetal Liver Programming following Nutrient Stress by Bowman, Caitlyn E., Selen Alpergin, Ebru S., Cavagnini, Kyle, Smith, Danielle M., Scafidi, Susanna, Wolfgang, Michael J.

“…The extreme metabolic demands of pregnancy require coordinated metabolic adaptations between mother and fetus to balance fetal growth and maternal health with…”
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Loss of ACOT7 potentiates seizures and metabolic dysfunction by Bowman, Caitlyn E, Selen Alpergin, Ebru S, Ellis, Jessica M, Wolfgang, Michael J

“…Neurons uniquely antagonize fatty acid utilization by hydrolyzing the activated form of fatty acids, long chain acyl-CoAs, via the enzyme acyl-CoA thioesterase…”
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The mitochondrial Ca2+ channel MCU is critical for tumor growth by supporting cell cycle progression and proliferation by Fernandez Garcia, Emily, Paudel, Usha, Noji, Michael C., Bowman, Caitlyn E., Rustgi, Anil K., Pitarresi, Jason R., Wellen, Kathryn E., Arany, Zolt, Weissenrieder, Jillian S., Foskett, J. Kevin

“…Introduction: The mitochondrial uniporter (MCU) Ca 2+ ion channel represents the primary means for Ca 2+ uptake by mitochondria. Mitochondrial matrix Ca 2+…”
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Regulation of maternal–fetal metabolic communication by Bowman, Caitlyn E., Arany, Zoltan, Wolfgang, Michael J.

“…Pregnancy may be the most nutritionally sensitive stage in the life cycle, and improved metabolic health during gestation and early postnatal life can reduce…”
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Metabolic perturbations after pediatric TBI: It's not just about glucose by Bowman, Caitlyn E., Scafidi, Joseph, Scafidi, Susanna

“…Improved patient survival following pediatric traumatic brain injury (TBI) has uncovered a currently limited understanding of both the adaptive and maladaptive…”
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Requirement for the Mitochondrial Pyruvate Carrier in Mammalian Development Revealed by a Hypomorphic Allelic Series by Bowman, Caitlyn E., Zhao, Liang, Hartung, Thomas, Wolfgang, Michael J.

“…Glucose and oxygen are two of the most important molecules transferred from mother to fetus during eutherian pregnancy, and the metabolic fates of these…”
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Etomoxir Inhibits Macrophage Polarization by Disrupting CoA Homeostasis by Divakaruni, Ajit S., Hsieh, Wei Yuan, Minarrieta, Lucía, Duong, Tin N., Kim, Kristen K.O., Desousa, Brandon R., Andreyev, Alexander Y., Bowman, Caitlyn E., Caradonna, Kacey, Dranka, Brian P., Ferrick, David A., Liesa, Marc, Stiles, Linsey, Rogers, George W., Braas, Daniel, Ciaraldi, Theodore P., Wolfgang, Michael J., Sparwasser, Tim, Berod, Luciana, Bensinger, Steven J., Murphy, Anne N.

“…Long-chain fatty acid (LCFA) oxidation has been shown to play an important role in interleukin-4 (IL-4)-mediated macrophage polarization (M(IL-4)). However,…”
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Role of the malonyl-CoA synthetase ACSF3 in mitochondrial metabolism by Bowman, Caitlyn E., Wolfgang, Michael J.

“…Malonyl-CoA is a central metabolite in fatty acid biochemistry. It is the rate-determining intermediate in fatty acid synthesis but is also an allosteric…”
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The Mammalian Malonyl-CoA Synthetase ACSF3 Is Required for Mitochondrial Protein Malonylation and Metabolic Efficiency by Bowman, Caitlyn E, Rodriguez, Susana, Selen Alpergin, Ebru S, Acoba, Michelle G, Zhao, Liang, Hartung, Thomas, Claypool, Steven M, Watkins, Paul A, Wolfgang, Michael J

“…Malonyl-coenzyme A (malonyl-CoA) is a central metabolite in mammalian fatty acid biochemistry generated and utilized in the cytoplasm; however, little is known…”
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SGLT2 Inhibitors Act Independently of SGLT2 to Confer Benefit for HFrEF in Mice by Berger, Justin H, Matsuura, Timothy R, Bowman, Caitlyn E, Taing, Renee, Patel, Jiten, Lai, Ling, Leone, Teresa C, Reagan, Jeffrey D, Haldar, Saptarsi M, Arany, Zoltan, Kelly, Daniel P

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Loss of CTRP5 improves insulin action and hepatic steatosis by Lei, Xia, Rodriguez, Susana, Petersen, Pia S, Seldin, Marcus M, Bowman, Caitlyn E, Wolfgang, Michael J, Wong, G William

“…The gene that encodes C1q/TNF-related protein 5 (CTRP5), a secreted protein of the C1q family, is mutated in individuals with late-onset retinal degeneration…”
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Fatty acid oxidation by the osteoblast is required for normal bone acquisition in a sex- and diet-dependent manner by Kim, Soohyun P, Li, Zhu, Zoch, Meredith L, Frey, Julie L, Bowman, Caitlyn E, Kushwaha, Priyanka, Ryan, Kathleen A, Goh, Brian C, Scafidi, Susanna, Pickett, Julie E, Faugere, Marie-Claude, Kershaw, Erin E, Thorek, Daniel L J, Clemens, Thomas L, Wolfgang, Michael J, Riddle, Ryan C

“…Postnatal bone formation is influenced by nutritional status and compromised by disturbances in metabolism. The oxidation of dietary lipids represents a…”
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The mitochondrial Ca 2+ channel MCU is critical for tumor growth by supporting cell cycle progression and proliferation by Fernandez Garcia, Emily, Paudel, Usha, Noji, Michael C, Bowman, Caitlyn E, Rustgi, Anil K, Pitarresi, Jason R, Wellen, Kathryn E, Arany, Zolt, Weissenrieder, Jillian S, Foskett, J Kevin

“…The mitochondrial uniporter (MCU) Ca ion channel represents the primary means for Ca uptake by mitochondria. Mitochondrial matrix Ca plays critical roles in…”
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