Search Results - "Bowles, D K"

Upregulation of intermediate-conductance Ca2+-activated K+ channel (IKCa1) mediates phenotypic modulation of coronary smooth muscle by Tharp, D L, Wamhoff, B R, Turk, J R, Bowles, D K

“…A hallmark of smooth muscle cell (SMC) phenotypic modulation in atherosclerosis and restenosis is suppression of SMC differentiation marker genes,…”
Get more information

Hypercholesterolemia abolishes voltage-dependent K+ channel contribution to adenosine-mediated relaxation in porcine coronary arterioles by Heaps, C L, Tharp, D L, Bowles, D K

“…Hypercholesterolemic patients display reduced coronary flow reserve in response to adenosine infusion. We previously reported that voltage-dependent K+ (Kv)…”
Get more information

Hypercholesterolemia inhibits L-type calcium current in coronary macro-, not microcirculation by Bowles, D. K, Heaps, C. L, Turk, J. R, Maddali, K. K, Price, E. M

“…1 Department of Biomedical Sciences and 2 Dalton Cardiovascular Research Center, University of Missouri, Columbia, Missouri 65211 Submitted 17 November 2003 ;…”
Get full text

L-type Voltage-Gated Ca2+ Channels Modulate Expression of Smooth Muscle Differentiation Marker Genes via a Rho Kinase/Myocardin/SRF–Dependent Mechanism by Wamhoff, B R, Bowles, D K, McDonald, O G, Sinha, S, Somlyo, A P, Somlyo, A V, Owens, G K

“…Vascular smooth muscle cell (SMC) contraction is mediated in part by calcium influx through L-type voltage-gated Ca channels (VGCC) and activation of the…”
Get full text

Alterations in PKC signaling underlie enhanced myogenic tone in exercise-trained porcine coronary resistance arteries by Korzick, D. H, Laughlin, M. H, Bowles, D. K

“…Departments of 1 Biomedical Sciences and 2 Medical Pharmacology and Physiology and 3 Dalton Cardiovascular Research Center, University of Missouri, Columbia,…”
Get full text

Endogenous testosterone increases L-type Ca2+ channel expression in porcine coronary smooth muscle by Bowles, D K, Maddali, K K, Ganjam, V K, Rubin, L J, Tharp, D L, Turk, J R, Heaps, C L

“…Evidence indicates that gender and sex hormonal status influence cardiovascular physiology and pathophysiology. We recently demonstrated increased L-type…”
Get more information

Gender influences coronary L-type Ca2+ current and adaptation to exercise training in miniature swine by Bowles, D. K

“…Department of Veterinary Biomedical Sciences, College of Veterinary Medicine and Dalton Cardiovascular Research Center, University of Missouri, Columbia,…”
Get full text

Mechanism of beneficial effects of physical activity on atherosclerosis and coronary heart disease by Bowles, D K, Laughlin, M H

Get full text

Exercise training improves metabolic response after ischemia in isolated working rat heart by Bowles, D K, Starnes, J W

“…Hearts from treadmill-trained and sedentary rats were perfused in the working heart mode. Mechanical and metabolite status was evaluated before ischemia, after…”
Get more information

Exercise training increases L-type calcium current density in coronary smooth muscle by Bowles, D K, Hu, Q, Laughlin, M H, Sturek, M

“…Exercise training produces numerous adaptations in the coronary circulation, including an increase in coronary tone, both in conduit and resistance arteries…”
Get full text

Exercise training increases K+-channel contribution to regulation of coronary arterial tone by Bowles, D. K, Laughlin, M. H, Sturek, M

“…Vascular Biology Laboratory, Dalton Cardiovascular Research Center, and Departments of Physiology and Veterinary Biomedical Sciences, University of Missouri,…”
Get full text

Syndrome of Inappropriate Antidiuretic Hormone in a Bulldog with Aspiration Pneumonia by Bowles, K.D., Brainard, B.M., Coleman, K.D.

“…Fluid, Electrolyte, and Acid-Base Disorders in Small Animal Practice, 4th ed. Granulomatous amebic meningoencephalitis causing the syndrome of inappropriate…”
Get full text

Exercise training attenuates coronary smooth muscle phenotypic modulation and nuclear Ca2+ signaling by Wamhoff, B R, Bowles, D K, Dietz, N J, Hu, Q, Sturek, M

“…Physical inactivity is an independent risk factor for coronary heart disease, yet the mechanism(s) of exercise-related cardioprotection remains unknown. We…”
Get more information

Vaginal Microbiota of Spayed Dogs with or without Recurrent Urinary Tract Infections by Hutchins, R.G, Vaden, S.L, Jacob, M.E, Harris, T.L, Bowles, K.D, Wood, M.W, Bailey, C.S

“…BACKGROUND: Limited information is available regarding the vaginal microbiota of normal spayed dogs and spayed dogs with recurrent UTIs. Vaginal lactic…”
Get full text

Exercise training improves cardiac function after ischemia in the isolated, working rat heart by Bowles, D K, Farrar, R P, Starnes, J W

“…The aim of this study was to determine whether exercise training produces a myocardium intrinsically more tolerant to ischemic-reperfusion injury. Male Fischer…”
Get full text

Heterogeneity of L-type calcium current density in coronary smooth muscle by Bowles, D K, Hu, Q, Laughlin, M H, Sturek, M

“…Heterogeneity of vascular responses to physiological and pharmacological stimuli has been demonstrated throughout the coronary circulation. Typically, this…”
Get full text

Exercise training alters the Ca2+ and contractile responses of coronary arteries to endothelin by Bowles, D K, Laughlin, M H, Sturek, M

“…We tested the hypothesis that alterations in myoplasmic free Ca2+ (Ca(m)) regulation in coronary smooth muscle after exercise training (Ex) underlie changes in…”
Get more information

Gender influences coronary L-type Ca(2+) current and adaptation to exercise training in miniature swine by Bowles, D K

“…Endurance exercise training increases smooth muscle L-type Ca(2+) current density in both resistance and proximal coronary arteries of female miniature swine…”
Get full text

Effect of downhill running on motoneuron pool excitability by Bulbulian, R, Bowles, D K

“…The purpose of this study was to compare alterations in motoneuron pool excitability after eccentric-biased (ECC-B) downhill running exercise with non-biased…”
Get more information

Coronary smooth muscle adaptation to exercise: does it play a role in cardioprotection? by Bowles, D. K., Wamhoff, B. R.

“…Substantial evidence exists supporting the role of chronic exercise in reducing the incidence and severity of coronary vascular disease. Physical inactivity is…”
Get full text