Search Results - "Bowler, R. P"

Trolox contributes to Nrf2-mediated protection of human and murine primary alveolar type II cells from injury by cigarette smoke by Messier, E M, Bahmed, K, Tuder, R M, Chu, H W, Bowler, R P, Kosmider, B

“…Cigarette smoke (CS) is a main risk factor for chronic obstructive pulmonary disease (COPD). Oxidative stress induced by CS causes DNA and lung damage…”
Get full text

Tumour necrosis factor gene polymorphisms are associated with COPD by Gingo, M. R, Silveira, L. J, Miller, Y. E, Friedlander, A. L, Cosgrove, G. P, Chan, E. D, Maier, L. A, Bowler, R. P

“…Tumour necrosis factor (TNF)-alpha has been shown to be an important factor in animal models of chronic obstructive pulmonary disease (COPD). However, human…”
Get full text

SELDI-TOF derived serum biomarkers failed to differentiate between patients with beryllium sensitisation and patients with chronic beryllium disease by Tooker, B C, Bowler, R P, Orcutt, J M, Maier, L A, Christensen, H M, Newman, L S

“…BackgroundPeople exposed to beryllium may develop beryllium sensitisation (BeS) and, in some cases, progress to chronic beryllium disease (CBD).ObjectivesThe…”
Get full text

Joint fluid antioxidants are decreased in osteoarthritic joints compared to joints with macroscopically intact cartilage and subacute injury by Regan, E.A., M.D., Ph.D, Bowler, R.P., M.D., Ph.D, Crapo, J.D., M.D

“…Summary Objective Excess reactive oxygen species and oxidative damage have been associated with the pathogenesis of osteoarthritis (OA). Extracellular…”
Get full text

Unique and shared systemic biomarkers for emphysema in Alpha-1 Antitrypsin deficiency and chronic obstructive pulmonary disease by Serban, K.A., Pratte, K.A., Strange, C., Sandhaus, R.A., Turner, A.M., Beiko, T., Spittle, D.A., Maier, L., Hamzeh, N., Silverman, E.K., Hobbs, B.D., Hersh, C.P., DeMeo, D.L., Cho, M.H., Bowler, R.P.

“…Alpha-1 Antitrypsin (AAT) deficiency (AATD), the most common genetic cause of emphysema presents with unexplained phenotypic heterogeneity in affected…”
Get full text

Oxidative stress in allergic respiratory diseases by Bowler, Russell P., Crapo, James D.

“…There is ample evidence that allergic disorders, such as asthma, rhinitis, and atopic dermatitis, are mediated by oxidative stress. Excessive exposure to…”
Get full text

Isolated pulmonary capillaritis and diffuse alveolar hemorrhage in rheumatoid arthritis and mixed connective tissue disease by Schwarz, M I, Zamora, M R, Hodges, T N, Chan, E D, Bowler, R P, Tuder, R M

“…To demonstrate that pulmonary capillaritis and diffuse alveolar hemorrhage (DAH) occur and are isolated to the lung and therefore not part of systemic…”
Get more information

Association of Systemic Inflammation with Depressive Symptoms in Individuals with COPD by Strollo, Hilary C, Nouraie, Seyed M, Hoth, Karin F, Riley, Craig M, Karoleski, Chad, Zhang, Yingze, Hanania, Nicola A, Bowler, Russell P, Bon, Jessica, Sciurba, Frank C

“…Depression is a prevalent comorbidity of chronic obstructive pulmonary disease (COPD) that, along with COPD, has been associated with inflammation. An…”
Get full text

Extracellular superoxide dismutase (EC-SOD) as a protective factor for risk of chronic obstructive pulmonary disease by Bowler, R. P, Hokanson, J, Taylor, M, Levy, S, Canaham, E. M, Regan, E, Wheeler, C, Nicks, M, Chan, E, Crapo, J. D

“…* Medicine, National Jewish Medical and Research Center, Denver, CO, USA # Preventive Medicine & Biometrics, University of Colorado at Denver Health Sciences…”
Get full text

Identifying a Heart Rate Recovery Criterion After a 6-Minute Walk Test in COPD by Zhao, Dongxing, Abbasi, Asghar, Casaburi, Richard, Adami, Alessandra, Tiller, Nicholas B, Yuan, Wei, Yee, Christopher, Jendzjowsky, Nicholas G, MacDonald, David M, Kunisaki, Ken M, Stringer, William W, Porszasz, Janos, Make, Barry J, Bowler, Russell P, Rossiter, Harry B

“…Slow heart rate recovery (HRR) after exercise is associated with autonomic dysfunction and increased mortality. What HRR criterion at 1-minute after a 6-minute…”
Get full text

Massive hemoptysis from a pulmonary artery aneurysm associated with an emphysematous bulla by Bowler, R P, Durham, J, Schwarz, M I

“…A 66-year-old man with a history of COPD and Aspergillus fumigatus infection developed massive hemoptysis. Pulmonary artery angiography revealed an aneurysm…”
Get more information

The Intracellular Proteolytic Processing of Extracellular Superoxide Dismutase (EC-SOD) is a Two-step Event by Olsen, Dorte Aa, Petersen, Steen V., Oury, Tim D., Valnickova, Zuzana, Thøgersen, Ida B., Kristensen, Torsten, Bowler, Russel P., Crapo, James D., Enghild, Jan J.

“…Extracellular superoxide dismutase (EC-SOD) is a tetramer composed of either intact (Trp 1 –Ala 222 ) or proteolytically cleaved (Trp 1 –Glu 209 )…”
Get full text

58 PLASMA EXTRACELLULAR SUPEROXIDE DISMUTASE IS DECREASED IN HIGH-ALTITUDE MOUNTAINEERS WHO ARE ENDURANCE TRAINED by Regan, E. A., Bowler, R. P., Crapo, J. D.

“…PurposeTo measure plasma concentrations of extracellular superoxide dismutase (EC-SOD) in healthy mature athletes.MethodsSubjects were identified at the annual…”
Get full text

Extracellular Superoxide Dismutase Attenuates Lung Injury after Hemorrhage by BOWLER, RUSSELL P, ARCAROLI, JOHN, CRAPO, JAMES D, ROSS, ARON, SLOT, JAN W, ABRAHAM, EDWARD

“…Reperfusion of the lung after hemorrhage generates free radicals such as superoxide (O(2)(.)) that may injure the lung; however, the relative importance of…”
Get full text

A catalytic antioxidant (AEOL 10150) attenuates expression of inflammatory genes in stroke by Bowler, Russell P, Sheng, Huaxin, Enghild, Jan J, Pearlstein, Robert D, Warner, David S, Crapo, James D

“…Oxidative stress is a major source of injury from cerebral ischemia and reperfusion. We hypothesized that a catalytic antioxidant AEOL 10150 [manganese (III)…”
Get full text

B56 SCAR WARS: INSIGHTS INTO MECHANISMS AND TREATMENTS OF PULMONARY FIBROSIS: Bleomycin Treated Mice Expressing The R213g Exctracelular Superoxide Dismutase (ec-Sod) Polymorphism Have Decreased Susceptibility To Lung Disease by Mouradian, G C, Thorn, T, Grayck, E, Bowler, R P

Get full text

B38 TALKING ABOUT COPD BIOMARKERS: The Association Of Plasma Biomarkers With Emphysema In Mz Alpha-1 Antitrypsin Phenotypes by Carolan, B J, Jacobson, S, Kechris, K, Bowler, R P

Get full text

C22 COPD PHENOTYPES: Integrated Real-Time Health Assessments To Stratify COPD Patients by Locantore, N, Bowler, R P, Herrud, T, Schnell, C, Allinder, M, Sung, R, Tal-Singer, R

“…With new advancements involving smart phones, device sensors, and activity monitors, we can capture and integrate symptoms, activity, and rescue inhaler use to…”
Get full text

C35 INNATE IMMUNE MECHANISMS IN COPD: Plasma Cytokines And Chemokines Are Associated With Airflow Obstruction And Exacerbations In The COPDgene Cohort by Bradford, E P, Jacobson, S, Hartman, B C, Keene, J, Bowler, R P

Get full text

B36 COME TOGETHER: COPD PHENOTYPES: Relationship Of Menthol Cigarett Smoking With COPD, Comorbidities, And CT Metrics by Park, S, Suh, Y, Lee, Y, Lee, H, Kim, S, Choe, Y, Bowler, R P

Get full text