Search Results - "Bowers, Emma C"

LINE-1 Cargo and Reverse Transcriptase Activity Profiles in Extracellular Vesicles from Lung Cancer Cells and Human Plasma by Bowers, Emma C, Motta, Alexandre, Knox, Ken, McKay, Brian S, Ramos, Kenneth S

“…Long Interspersed Element-1 (LINE-1) is an oncogenic human retrotransposon that 'copies and pastes' DNA into new locations via reverse transcription. Given…”
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Long Interspersed Nuclear Element-1 Analytes in Extracellular Vesicles as Tools for Molecular Diagnostics of Non-Small Cell Lung Cancer by Bowers, Emma C, Cavalcante, Alexandre M, Nguyen, Kimberly, Li, Can, Wang, Yingshan, El-Zein, Randa, Chen, Shu-Hsia, Kim, Min P, McKay, Brian S, Ramos, Kenneth S

“…Aberrant expression of the oncogenic retrotransposon LINE-1 is a hallmark of various cancer types, including non-small cell lung cancers (NSCLCs). Here, we…”
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Scope and financial impact of unpublished data and unused samples among U.S. academic and government researchers by Bowers, Emma C., Stephenson, Jimena, Furlong, Melissa, Ramos, Kenneth S.

“…Unpublished data and unused samples are common byproducts of research activity, but little is known about the scope and economic impact of their disuse. To…”
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ERK1/2 and p38 regulate inter-individual variability in ozone-mediated IL-8 gene expression in primary human bronchial epithelial cells by Bowers, Emma C., McCullough, Shaun D., Morgan, David S., Dailey, Lisa A., Diaz-Sanchez, David

“…Inter-individual variability is observed in all biological responses; however this variability is difficult to model and its underlying mechanisms are often…”
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Linking the Epigenome with Exposure Effects and Susceptibility: The Epigenetic Seed and Soil Model by Bowers, Emma C, McCullough, Shaun D

“…The epigenome is a dynamic mediator of gene expression that shapes the way that cells, tissues, and organisms respond to their environment. Initial studies in…”
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In vitro models of exosome biology and toxicology: New frontiers in biomedical research by Bowers, Emma C., Hassanin, Abeer A.I., Ramos, Kenneth S.

“…Exosomes are secreted membrane-bound vesicles containing a cargo of curated nucleic acids, proteins, and lipids that can alter gene expression in recipient…”
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Ozone Responsive Gene Expression as a Model for Describing Repeat Exposure Response Trajectories and Interindividual Toxicodynamic Variability In Vitro by Bowers, Emma C, Martin, Elizabeth M, Jarabek, Annie M, Morgan, David S, Smith, Hannah J, Dailey, Lisa A, Aungst, Emily R, Diaz-Sanchez, David, McCullough, Shaun D

“…Abstract Inhaled chemical/material exposures are a ubiquitous part of daily life around the world. There is a need to evaluate potential adverse effects of…”
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Precision prevention: A focused response to shifting paradigms in healthcare by Ramos, Kenneth S, Bowers, Emma C, Tavera-Garcia, Marco A, Ramos, Irma N

“…Human health and disease are defined at the intersection of molecules, environment, and lifestyle, which combined determine phenotypic outcomes. To date, most…”
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Baseline Chromatin Modification Levels May Predict Interindividual Variability in Ozone-Induced Gene Expression by McCullough, Shaun D, Bowers, Emma C, On, Doan M, Morgan, David S, Dailey, Lisa A, Hines, Ronald N, Devlin, Robert B, Diaz-Sanchez, David

“…Traditional toxicological paradigms have relied on factors such as age, genotype, and disease status to explain variability in responsiveness to toxicant…”
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Using Chromatin Immunoprecipitation in Toxicology: A Step-by-Step Guide to Increasing Efficiency, Reducing Variability, and Expanding Applications by McCullough, Shaun D, On, Doan M, Bowers, Emma C

“…Histone modifications work in concert with DNA methylation to regulate cellular structure, function, and response to environmental stimuli. More than 130…”
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