Search Results - "Bowen, Meryn"

99m-Technetium carbohydrate conjugates as potential agents in molecular imaging by Bowen, Meryn L, Orvig, Chris

“…This feature article covers recent reports of work towards the development of (99m)Tc-carbohydrate based agents for use in SPECT imaging, particularly of…”
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Synthesis, Characterization, and Metal Coordinating Ability of Multifunctional Carbohydrate-Containing Compounds for Alzheimer's Therapy by Storr, Tim, Merkel, Michael, Song-Zhao, George X, Scott, Lauren E, Green, David E, Bowen, Meryn L, Thompson, Katherine H, Patrick, Brian O, Schugar, Harvey J, Orvig, Chris

“…Dysfunctional interactions of metal ions, especially Cu, Zn, and Fe, with the amyloid-β (Aβ) peptide are hypothesized to play an important role in the etiology…”
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Combating Alzheimer's Disease With Multifunctional Molecules Designed for Metal Passivation by Schugar, Harvey, Green, David E., Bowen, Meryn L., Scott, Lauren E., Storr, Tim, Böhmerle, Karin, Thomas, Fancy, Allen, David D., Lockman, Paul R., Merkel, Michael, Thompson, Katherine H., Orvig, Chris

“…A trifunctional approach: 3‐hydroxy‐4‐pyridinones that contain phenol groups for antioxidant functionality are further elaborated with pendant glucosyl…”
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In vitro studies of 3-hydroxy-4-pyridinones and their glycosylated derivatives as potential agents for Alzheimer's disease by Green, David E, Bowen, Meryn L, Scott, Lauren E, Storr, Tim, Merkel, Michael, Böhmerle, Karin, Thompson, Katherine H, Patrick, Brian O, Schugar, Harvey J, Orvig, Chris

“…Glycosides of 3-hydroxy-4-pyridinones were synthesized and characterized by mass spectrometry, elemental analysis, (1)H and (13)C NMR spectroscopy, and in one…”
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Glycosylated tetrahydrosalens as multifunctional molecules for Alzheimer's therapy by Storr, Tim, Scott, Lauren E, Bowen, Meryn L, Green, David E, Thompson, Katherine H, Schugar, Harvey J, Orvig, Chris

“…The tetrahydrosalens N,N'-bis(2-hydroxybenzyl)-ethane-1,2-diamine ((2)(1)), N,N'-bis(2-hydroxybenzyl)-(-)-1,2-cyclohexane-(1R,2R)-diamine ((2)(2)),…”
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Glucosamine conjugates bearing N,N,O-donors: potential imaging agents utilizing the [M(CO)3]+ core (M = Re, Tc) by Bowen, Meryn L, Lim, Nathaniel C, Ewart, Charles B, Misri, Ripen, Ferreira, Cara L, Häfeli, Urs, Adam, Michael J, Orvig, Chris

“…The design rationale, synthesis and radiolabeling evaluation of four glucosamine conjugated ligands for the [(99m)Tc(CO)(3)](+) core is described. The…”
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Long-chain rhenium and technetium glucosamine conjugates by Bowen, Meryn L, Chen, Zhen-Feng, Roos, Adrienne M, Misri, Ripen, Häfeli, Urs, Adam, Michael J, Orvig, Chris

“…A series of five glucosamine-conjugated organometallic complexes of the tricarbonyl cores of technetium-99m and rhenium were made. Glucosamine was derivatized…”
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Pyridine−tert-Nitrogen−Phenol Ligands: N,N,O-Type Tripodal Chelates for the [M(CO)3]+ Core (M = Re, Tc) by Lim, Nathaniel C, Ewart, Charles B, Bowen, Meryn L, Ferreira, Cara L, Barta, Cheri A, Adam, Michael J, Orvig, Chris

“…The design rationale, synthesis, and preliminary radiolabeling evaluation of new N,N,O-type pyridyl−tert-nitrogen−phenol ligands for the [M(CO)3]+ core, where…”
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Cationic technetium and rhenium complexes with pendant carbohydrates by Ferreira, Cara L., Marques, Fabio L.N., Okamoto, Miriam R.Y., Otake, Andréia H., Sugai, Yuko, Mikata, Yuji, Storr, Tim, Bowen, Meryn, Yano, Shigenobu, Adam, Michael J., Chammas, Roger, Orvig, Chris

“…Three carbohydrate conjugated dipicolylamine chelators, 2-bis(2-pyridinylmethyl)amino)ethyl 1-deoxy-1-thio-β-D-glucopyranoside ( L 1 ),…”
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Combating Alzheimer's Disease With Multifunctional Molecules Designed for Metal Passivation by Schugar, Harvey, Green, David E., Bowen, Meryn L., Scott, Lauren E., Storr, Tim, Böhmerle, Karin, Thomas, Fancy, Allen, David D., Lockman, Paul R., Merkel, Michael, Thompson, Katherine H., Orvig, Chris

“…Ein trifunktioneller Ansatz: 3‐Hydroxy‐4‐pyridinone mit antioxidativ wirkenden Phenolresten wurden für eine bessere Blut‐Hirn‐Gängigkeit zusätzlich mit…”
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Combating Alzheimer's Disease With Multifunctional Molecules Designed for Metal Passivation by Schugar, Harvey, Green, David E., Bowen, Meryn L., Scott, Lauren E., Storr, Tim, Böhmerle, Karin, Thomas, Fancy, Allen, David D., Lockman, Paul R., Merkel, Michael, Thompson, Katherine H., Orvig, Chris

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