Search Results - "Bowen, Larry E"

Cigarette Smoke Induces Systemic Defects in Cystic Fibrosis Transmembrane Conductance Regulator Function by VAMSEE RAJU, S, JACKSON, Patricia L, JONES, Caleb W, BOYDSTON, Jeremy A, CLANCY, J. P, BOWEN, Larry E, ACCURSO, Frank J, BLALOCK, J. Edwin, DRANSFIELD, Mark T, ROWE, Steven M, COURVILLE, Clifford A, McNICHOLAS, Carmel M, SLOANE, Peter A, SABBATINI, Gina, TIDWELL, Sherry, LI PING TANG, BO LIU, FORTENBERRY, James A

“…Several extrapulmonary disorders have been linked to cigarette smoking. Smoking is reported to cause cystic fibrosis transmembrane conductance regulator (CFTR)…”
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Development of an in vitro approach to point-of-contact inhalation toxicity testing of volatile compounds, using organotypic culture and air-liquid interface exposure by Mistry, Artik, Bowen, Larry E., Dzierlenga, Michael W., Hartman, Jessica K., Slattery, Scott D.

“…In vitro chemical risk assessment using human cells is emerging as an alternative to in vivo animal testing with reduced costs, fewer animal welfare concerns,…”
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Development of a murine nose-only inhalation model of influenza: comparison of disease caused by instilled and inhaled A/PR/8/34 by Bowen, Larry E, Rivers, Katie, Trombley, John E, Bohannon, J Kyle, Li, Shixiong X, Boydston, Jeremy A, Eichelberger, Maryna C

“…Influenza continues to cause widespread disease and death during winter months. In preclinical studies to evaluate the potential efficacy of drugs and…”
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Pulmonary Delivery of Ceftazidime for the Treatment of Melioidosis in a Murine Model by Ruiz, Sara I, Bowen, Larry E, Bailey, Mark M, Berkland, Cory

“…Burkholderia pseudomallei, the etiological agent responsible for melioidosis, exhibits a great public health toll in its endemic regions. The elevation of B…”
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Formulation and Characterization of Nanocluster Ceftazidime for the Treatment of Acute Pulmonary Melioidosis by Ruiz, Sara I, El-Gendy, Nashwa, Bowen, Larry E, Berkland, Cory, Bailey, Mark M

“…Melioidosis is an infectious disease caused by Burkholderia pseudomallei. The disease is responsible for a high proportion of human pneumonia and fatal…”
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INHALATION ADMINISTRATION OF ALL-TRANS-RETINOIC ACID FOR TREATMENT OF ELASTASE-INDUCED PULMONARY EMPHYSEMA IN FISCHER 344 RATS by March, Thomas H., Cossey, Patricia Y., Esparza, Dolores C., Dix, Kelly J., McDonald, Jacob D., Bowen, Larry E.

“…A past study demonstrated that all-trans-retinoic acid (ATRA) treatment by intraperitoneal injection in a rat model of elastase-induced emphysema caused tissue…”
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Comparison of the effectiveness of antibody and cell-mediated immunity against inhaled and instilled influenza virus challenge by Rivers, Katie, Bowen, Larry E, Gao, Jin, Yang, Kevin, Trombley, John E, Bohannon, J Kyle, Eichelberger, Maryna C

“…BACKGROUND: To evaluate immunity against influenza, mouse challenge studies are typically performed by intranasal instillation of a virus suspension to…”
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Parental allergic status influences the risk of developing allergic sensitization and an asthmatic‐like phenotype in canine offspring by Barrett, Edward G., Rudolph, Karin, Bowen, Larry E., Bice, David E.

“…Summary Increasing evidence suggests that parental allergic status, especially that of the mother, may play a unique and important role in influencing the…”
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PRELIMINARY ASSESSMENT OF A PYROTECHNICALLY GENERATED AEROSOL FIRE SUPPRESSANT by Smith, Eldon A, Kimmel, Edgar C, Bowen, Larry E, Reboulet, James E, Carpenter, Robert L

“…Fischer 344 rats (approximately 250-300 g) were exposed to the aerosol resulting from the pyrolysis of SFE Formulation A at a loading of 50 or 80 g/ m3…”
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Effect of Inhaled Ultrafine Carbon Particles on the Allergic Airway Response in Ragweed-Sensitized Dogs by Barrett, Edward G., Rudolph, Karin, Bowen, Larry E., Muggenburg, Bruce A., Bice, David E.

“…Episodic increases in air pollution have been associated with the exacerbation of asthma symptoms. Ultrafine particles are a component of air pollution and may…”
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Pulmonary immunity to ragweed in a beagle dog model of allergic asthma by REDMAN, Tamara K, RUDOLPH, Karin, BARR, Edward B, BOWEN, Larry E, MUGGENBURG, Bruce A, BICE, David E

“…To create an allergy model in the dog, allergic Beagles with high levels of serum immunoglobulin E (IgE) and eosinophilia were bred; resulting puppies were…”
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Acute Neurobehavioral Effects in Rats from Exposure to HFC 134a or CFC 12 by Ritchie, Glenn D, Kimmel, Edward C, Bowen, Larry E, Reboulet, James E, Rossi, John

“…1,1,1,2-Tetrafluoroethane (HFC 134a), a chlorine-free hydrofluoroalkane, is internationally replacing billions of pounds of dichlorodifluoromethane (CFC 12)…”
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Inhalation of Insulin (Exubera®) Augments the Efficiency of Muscle Glucose Uptake In Vivo by Edgerton, Dale S, Doss, Neal, Scott, Melanie, Bowen, Larry E

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Effects of strain and treatment with inhaled aII-trans-retinoic acid on cigarette smoke-induced pulmonary emphysema in mice by March, Thomas H, Bowen, Larry E, Finch, Gregory L, Nikula, Kristen J, Wayne, Bonnie J, Hobbs, Charles H

“…Models of emphysema produced by exposing animals to cigarette smoke (CS) have potential for use in testing treatments of this disease. To better characterize…”
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PULMONARY IMMUNITY TO RAGWEED IN A BEAGLE DOG MODEL OF ALLERGIC ASTHMA by Tamara K. Redman, Karin Rudolph, Edward B. Barr, Larry E. Bowen, Bruce A. Muggenburg, David E. Bice

“…To create an allergy model in the dog, allergic Beagles with high levels of serum immunoglobulin E(IgE) and eosinophilia were bred; resulting puppies were…”
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Evaluation of the Respiratory Tract after Acute Exposure to a Pyrotechnically Generated Aerosol Fire Suppressant by Smith, Eldon A., Kimmel, Edgar C., English, Jeffrey H, Bowen, Larry E., Reboulet, James E., Carpenter, Robert L.

“…Fischer 344 rats (250–300 g) were exposed to the resulting aerosols from the pyrolysis of Spectrex Fire Extinguishant (SFE) Formulation A, a pyrotechnically…”
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