Search Results - "Bowen, J.Phillip"
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Design, synthesis, and biological evaluation of angiogenesis inhibitors: aromatic enone and dienone analogues of curcumin
Published in Bioorganic & medicinal chemistry letters (06-01-2003)“…The quest to find new antitumor compounds is an ongoing research endeavor in many laboratories around the world. The use of small-molecule angiogenesis…”
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Novel furano analogues of duocarmycin C1 and C2: design, synthesis, and biological evaluation of seco-iso-Cyclopropylfurano[2,3- e]indoline ( seco-iso-CFI) and seco-Cyclopropyltetrahydrofurano[2,3- f]quinoline ( seco-CFQ) analogues
Published in Bioorganic & medicinal chemistry (01-09-2002)“…The design, synthesis and biological evaluation of novel seco-iso-cyclopropylfurano[2,3- e]indoline ( seco-iso-CFI) and the…”
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An efficient synthesis of 2-aryl and 2-alkenyl-3-alkoxy-cyclohexenones by a modified Stille reaction
Published in Tetrahedron letters (15-01-1999)“…A general direct procedure for the synthesis of 2-aryl and 2-alkenyl-3-alkoxy-cyclohexenones using a modified Stille coupling is described. A general, direct…”
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Sequence selective recognition of DNA by hairpin conjugates of a racemic seco-cyclopropaneindoline-2-benzofurancarboxamide and polyamides
Published in Bioorganic & medicinal chemistry letters (19-08-2002)“…Conjugates of racemic seco-cyclopropaneindoline-2-benzofurancarboxamide (CI-Bf) and four diamides (ImIm 1, ImPy 2, PyIm 3, and PyPy 4, where Py is pyrrole, and…”
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Density functional and ab initio studies on N-acetyl-duocarmycin SA: Insight into its DNA interaction properties
Published in Bioorganic & medicinal chemistry (01-02-2000)Get full text
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Requirements for high affinity binding of glycine analogs to the glycine site of the NMDA receptor complex
Published in European journal of pharmacology (15-09-1993)“…Correlation of the isopotential contours of the optimized conformations of a series of alpha-amino acids, in their neutral and zwitterionic forms, with their…”
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Ab initio calculations and molecular mechanics (MM3) force field development for sulfonamide and its alkyl derivatives
Published in Journal of molecular structure. Theochem (01-08-1997)“…Sulfonamide and eight of its alkyl derivatives were studied with ab initio calculations ( gaussian 94) at the MP2/6–31 + G ∗ level of theory. Based on the…”
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