Search Results - "Bowen, David G."

Liver-Resident Memory CD8+ T Cells Form a Front-Line Defense against Malaria Liver-Stage Infection by Fernandez-Ruiz, Daniel, Ng, Wei Yi, Holz, Lauren E., Ma, Joel Z., Zaid, Ali, Wong, Yik Chun, Lau, Lei Shong, Mollard, Vanessa, Cozijnsen, Anton, Collins, Nicholas, Li, Jessica, Davey, Gayle M., Kato, Yu, Devi, Sapna, Skandari, Roghieh, Pauley, Michael, Manton, Jonathan H., Godfrey, Dale I., Braun, Asolina, Tay, Szun Szun, Tan, Peck Szee, Bowen, David G., Koch-Nolte, Friedrich, Rissiek, Björn, Carbone, Francis R., Crabb, Brendan S., Lahoud, Mireille, Cockburn, Ian A., Mueller, Scott N., Bertolino, Patrick, McFadden, Geoffrey I., Caminschi, Irina, Heath, William R.

“…In recent years, various intervention strategies have reduced malaria morbidity and mortality, but further improvements probably depend upon development of a…”
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A Liver Capsular Network of Monocyte-Derived Macrophages Restricts Hepatic Dissemination of Intraperitoneal Bacteria by Neutrophil Recruitment by Sierro, Frederic, Evrard, Maximilien, Rizzetto, Simone, Melino, Michelle, Mitchell, Andrew J., Florido, Manuela, Beattie, Lynette, Walters, Shaun B., Tay, Szun Szun, Lu, Bo, Holz, Lauren E., Roediger, Ben, Wong, Yik Chun, Warren, Alessandra, Ritchie, William, McGuffog, Claire, Weninger, Wolfgang, Le Couteur, David G., Ginhoux, Florent, Britton, Warwick J., Heath, William R., Saunders, Bernadette M., McCaughan, Geoffrey W., Luciani, Fabio, MacDonald, Kelli P.A., Ng, Lai Guan, Bowen, David G., Bertolino, Patrick

“…The liver is positioned at the interface between two routes traversed by pathogens in disseminating infection. Whereas blood-borne pathogens are efficiently…”
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A hepatic network of dendritic cells mediates CD4 T cell help outside lymphoid organs by English, Kieran, Kwan, Rain, Holz, Lauren E., McGuffog, Claire, Krol, Jelte M. M., Kempe, Daryan, Kaisho, Tsuneyasu, Heath, William R., Lisowski, Leszek, Biro, Maté, McCaughan, Geoffrey W., Bowen, David G., Bertolino, Patrick

“…While CD4 + T cells are a prerequisite for CD8 + T cell-mediated protection against intracellular hepatotropic pathogens, the mechanisms facilitating the…”
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Induction Phase of Spontaneous Liver Transplant Tolerance by McCaughan, Geoffrey W, Bowen, David G, Bertolino, Patrick J

“…The liver has long been known to possess tolerogenic properties. Early experiments in liver transplantation demonstrated that in animal models, hepatic…”
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The liver contains distinct interconnected networks of CX3CR1+ macrophages, XCR1+ type 1 and CD301a+ type 2 conventional dendritic cells embedded within portal tracts by English, Kieran, Tan, Sioh Yang, Kwan, Rain, Holz, Lauren E, Sierro, Frederic, McGuffog, Claire, Kaisho, Tsuneyasu, Heath, William R, MacDonald, Kelli PA, McCaughan, Geoffrey W, Bowen, David G, Bertolino, Patrick

“…Portal tracts are key intrahepatic structures where leukocytes accumulate during immune responses. They contain the blood inflow, which includes portal blood…”
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Students' perceived research skills development and satisfaction after completion of a mandatory research project: results from five cohorts of the Sydney medical program by Kaur, Rajneesh, Hakim, Jonathan, Jeremy, Richmond, Coorey, Genevieve, Kalman, Eszter, Jenkin, Rebekah, Bowen, David G, Hart, Joanne

“…Research activities undertaken during University studies contribute to preparation of medical students for practice of evidence-based medicine. This study…”
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Antigen expression level threshold tunes the fate of CD8 T cells during primary hepatic immune responses by Tay, Szun Szun, Wong, Yik Chun, McDonald, David M, Wood, Nicole A W, Roediger, Ben, Sierro, Frederic, Mcguffog, Claire, Alexander, Ian E, Bishop, G Alex, Gamble, Jennifer R, Weninger, Wolfgang, McCaughan, Geoffrey W, Bertolino, Patrick, Bowen, David G

“…CD8 T-cell responses to liver-expressed antigens range from deletional tolerance to full effector differentiation resulting in overt hepatotoxicity. The…”
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Hepatocyte entry leads to degradation of autoreactive CD8 T cells by Benseler, Volker, Warren, Alessandra, Vo, Michelle, Holz, Lauren E, Tay, Szun S, Le Couteur, David G, Breen, Eamon, Allison, Anthony C, van Rooijen, Nico, McGuffog, Claire, Schlitt, Hans J, Bowen, David G, McCaughan, Geoffrey W, Bertolino, Patrick

“…Although most self-reactive T cells are eliminated in the thymus, mechanisms to inactivate or control T cells specific for extrathymic antigens are required…”
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Supplementation with Synbiotics and/or Branched Chain Amino Acids in Hepatic Encephalopathy: A Pilot Randomised Placebo-Controlled Clinical Study by Vidot, Helen, Cvejic, Erin, Finegan, Liam J, Shores, E Arthur, Bowen, David G, Strasser, Simone I, McCaughan, Geoffrey W, Carey, Sharon, Allman-Farinelli, Margaret, Shackel, Nicholas A

“…Hepatic encephalopathy (HE) is common in patients with cirrhosis and is characterised by reduced hepatic ammonia clearance. This is accompanied by alterations…”
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Association between vessels that encapsulate tumour clusters vascular pattern and hepatocellular carcinoma recurrence following liver transplantation by Dennis, Claude, Prince, David S., Moayed-Alaei, Leila, Remash, Devika, Carr-Boyd, Emily, Bowen, David G., Strasser, Simone I., Crawford, Michael, Pulitano, Carlo, Kench, James, McCaughan, Geoffrey W., McKenzie, Catriona, Liu, Ken

“…BackgroundVessels that encapsulate tumor clusters (VETC) is a novel vascular pattern seen on hepatocellular carcinoma (HCC) histology which has been shown to…”
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CD147 mediates intrahepatic leukocyte aggregation and determines the extent of liver injury by Yee, Christine, Main, Nathan M, Terry, Alexandra, Stevanovski, Igor, Maczurek, Annette, Morgan, Alison J, Calabro, Sarah, Potter, Alison J, Iemma, Tina L, Bowen, David G, Ahlenstiel, Golo, Warner, Fiona J, McCaughan, Geoffrey W, McLennan, Susan V, Shackel, Nicholas A

“…Chronic inflammation is the driver of liver injury and results in progressive fibrosis and eventual cirrhosis with consequences including both liver failure…”
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Circulating fibroblast activation protein activity and antigen levels correlate strongly when measured in liver disease and coronary heart disease by Uitte de Willige, Shirley, Keane, Fiona M, Bowen, David G, Malfliet, Joyce J M C, Zhang, H Emma, Maneck, Bharvi, McCaughan, Geoffrey W, Leebeek, Frank W G, Rijken, Dingeman C, Gorrell, Mark D

“…Circulating fibroblast activation protein (cFAP) is a constitutively active enzyme expressed by activated fibroblasts that has both dipeptidyl peptidase and…”
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Corrigendum: Malaria and the liver: immunological hide-and-seek or subversion of immunity from within? by Bertolino, Patrick, Bowen, David G

“…[This corrects the article on p. 41 in vol. 6, PMID: 25741320.]…”
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Tolerance in liver transplantation by Alex Bishop, G., PhD, Bertolino, Patrick D., PhD, Bowen, David G., MBBS, PhD, McCaughan, Geoffrey W., MBBS, PhD

“…Operational tolerance (OT) in liver transplant patients occurs much more frequently than OT of other transplanted organs; however the rate of OT varies…”
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Zone defence – the gut microbiota position macrophages for optimal liver protection by English, Kieran, Bowen, David G, Bertolino, Patrick

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Molecular and Cellular Aspects of Hepatitis C Virus Reinfection After Liver Transplantation : How the Early Phase Impacts on Outcomes by MCCAUGHAN, Geoffrey W, SHACKEL, Nicholas A, BERTOLINO, Patrick, BOWEN, David G

“…Hepatitis C virus (HCV)-related liver disease postliver transplantation is associated with an accelerated course in comparison with that observed in the…”
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Adaptive immune responses in acute and chronic hepatitis C virus infection by Walker, Christopher M, Bowen, David G

“…The hepatitis C virus (HCV) persists in the majority of infected individuals and is a significant cause of human illness and death globally. Recent studies…”
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Analysis of human liver disease using a cluster of differentiation (CD) antibody microarray by Rahman, Wassim, Huang, Pauline, Belov, Larissa, Chrisp, Jeremy S., Christopherson, Richard I., Stapelberg, Peter M., Warner, Fiona J., George, Jacob, Bowen, David G., Strasser, Simone I., Koorey, David, Sharland, Alexandra F., McCaughan, Geoffrey W., Shackel, Nicholas A.

“…Background A CD antibody microarray has been previously developed allowing semi‐quantitative identification of greater than 80 CD antigens on circulating…”
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Variable Patterns of Programmed Death-1 Expression on Fully Functional Memory T Cells after Spontaneous Resolution of Hepatitis C Virus Infection by BOWEN, David G, SHOUKRY, Naglaa H, WUCHERPFENNIG, Kai W, HOUGHTON, Michael, WALKER, Christopher M, GRAKOUI, Arash, FULLER, Michael J, CAWTHON, Andrew G, DONG, Christine, HASSELSCHWERT, Dana L, BRASKY, Kathleen M, FREEMAN, Gordon J, SETH, Nilufer P

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Immune outcomes in the liver: Is CD8 T cell fate determined by the environment? by Wong, Yik Chun, Tay, Szun Szun, McCaughan, Geoffrey W, Bowen, David G, Bertolino, Patrick

“…Summary The liver is known for its tolerogenic properties. This unique characteristic is associated with persistent infection of the liver by the hepatitis B…”
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