Search Results - "Bowdridge, Elizabeth C."
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E-Cigarette Use: Device Market, Study Design, and Emerging Evidence of Biological Consequences
Published in International journal of molecular sciences (18-11-2021)“…Electronic cigarettes are frequently viewed as a safer alternative to conventional cigarettes; however, evidence to support this perspective has not…”
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Maternal Engineered Nanomaterial Inhalation During Gestation Disrupts Vascular Kisspeptin Reactivity
Published in Toxicological sciences (01-06-2019)“…Abstract Maternal engineered nanomaterial (ENM) inhalation is associated with uterine vascular impairments and endocrine disruption that may lead to altered…”
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Nano-titanium dioxide inhalation exposure during gestation drives redox dysregulation and vascular dysfunction across generations
Published in Particle and fibre toxicology (09-03-2022)“…Pregnancy is associated with many rapid biological adaptations that support healthy development of the growing fetus. One of which is critical to fetal health…”
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Editorial: Getting to the heart of developmental toxicities
Published in Frontiers in toxicology (2023)Get full text
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Whole-body inhalation of nano-sized carbon black: a surrogate model of military burn pit exposure
Published in BMC research notes (11-08-2022)“…Chronic multisymptom illness (CMI) is an idiopathic disease affecting thousands of U.S. Veterans exposed to open-air burn pits emitting aerosolized particulate…”
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Kisspeptin, Neurokinin B, and Dynorphin Expression during Pubertal Development in Female Sheep
Published in Biology (Basel, Switzerland) (30-09-2021)“…The neural mechanisms underlying increases in gonadotropin-releasing hormone (GnRH) and luteinizing hormone (LH) secretion that drive puberty onset are…”
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Maternal nano-titanium dioxide inhalation exposure alters placental cyclooxygenase and oxidant balance in a sexually dimorphic manner
Published in Advances in redox research : an official journal of the Society for Redox Biology and Medicine and the Society for Free Radical Research-Europe (01-04-2024)“…•Greater impacts on redox balance in fetal female labyrinth zone (LZ) of the placenta after maternal nanomaterial inhalation exposure.•Decreased xanthine…”
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Maternal nano-titanium dioxide inhalation alters fetoplacental outcomes in a sexually dimorphic manner
Published in Frontiers in toxicology (06-03-2023)“…The placenta plays a critical role in nutrient-waste exchange between the maternal and fetal circulations, thus functioning as an interface that profoundly…”
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Composable Microfluidic Plates (cPlate): A Simple and Scalable Fluid Manipulation System for Multiplexed Enzyme-Linked Immunosorbent Assay (ELISA)
Published in Analytical chemistry (Washington) (26-01-2021)“…Enzyme-linked immunosorbent assay (ELISA) is the gold standard method for protein biomarkers. However, scaling up ELISA for multiplexed biomarker analysis is…”
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Lesions of KNDy and Kiss1R Neurons in the Arcuate Nucleus Produce Different Effects on LH Pulse Patterns in Female Sheep
Published in Endocrinology (Philadelphia) (23-09-2023)“…Abstract The current model for the synchronization of GnRH neural activity driving GnRH and LH pulses proposes that a set of arcuate (ARC) neurons that contain…”
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The effect of NK3-Saporin injection within the arcuate nucleus on puberty, the LH surge, and the response to Senktide in female sheep
Published in Biology of reproduction (10-02-2024)“…The timing of puberty onset is reliant on increased gonadotropin-releasing hormone (GnRH). This elicits a corresponding increase in luteinizing hormone (LH)…”
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Breed-specific differences in the immune response to lipopolysaccharide in ewes
Published in Journal of animal science (29-09-2018)“…Abstract Innate immune response to a lipopolysaccharide (LPS) challenge varies among sheep breeds. How different breeds respond to bacterial infections impacts…”
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Maternal titanium dioxide nanomaterial inhalation exposure compromises placental hemodynamics
Published in Toxicology and applied pharmacology (15-03-2019)“…The fetal consequences of gestational engineered nanomaterial (ENM) exposure are unclear. The placenta is a barrier protecting the fetus and allowing transfer…”
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Nanomaterial Inhalation During Pregnancy Alters Systemic Vascular Function in a Cyclooxygenase-Dependent Manner
Published in Toxicological sciences (28-07-2022)“…Abstract Pregnancy requires rapid adaptations in the uterine microcirculation to support fetal development. Nanomaterial inhalation is associated with…”
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Localization of kisspeptin, NKB, and NK3R in the hypothalamus of gilts treated with the progestin altrenogest
Published in Biology of reproduction (01-10-2021)“…Mechanisms in the brain controlling secretion of gonadotropin hormones in pigs, particularly luteinizing hormone (LH), are poorly understood. Kisspeptin is a…”
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Evidence That the LH Surge in Ewes Involves Both Neurokinin B-Dependent and -Independent Actions of Kisspeptin
Published in Endocrinology (Philadelphia) (01-12-2019)“…Recent evidence has implicated neurokinin B (NKB) signaling in the retrochiasmatic area (RCh) of the ewe in the LH surge. To test this hypothesis, we first…”
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Maternal Nanomaterial Inhalation Exposure: Critical Gestational Period in the Uterine Microcirculation is Angiotensin II Dependent
Published in Cardiovascular toxicology (01-02-2022)“…Maternal inhalation exposure to engineered nanomaterials (ENM) has been associated with microvascular dysfunction and adverse cardiovascular responses…”
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Morphological and functional evidence for sexual dimorphism in neurokinin B signalling in the retrochiasmatic area of sheep
Published in Journal of neuroendocrinology (01-07-2020)“…Neurokinin B (NKB) is critical for fertility in humans and stimulates gonadotrophin‐releasing hormone/luteinising hormone (LH) secretion in several species,…”
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Activation of Adenosine Monophosphate-Activated Protein Kinase Is an Additional Mechanism That Participates in Mediating Inhibitory Actions of Prostaglandin F2Alpha in Mature, but Not Developing, Bovine Corpora Lutea
Published in Biology of reproduction (01-07-2015)“…Elevated cytosolic calcium and protein kinase C are well-established mediators of luteolytic actions of prostaglandin F2alpha (PGF2alpha). The objectives of…”
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Activation of Adenosine Monophosphate-Activated Protein Kinase Is an Additional Mechanism That Participates in Mediating Inhibitory Actions of Prostaglandin F2Alpha in Mature, but Not Developing, Bovine Corpora Lutea1
Published in Biology of reproduction (01-07-2015)“…Elevated cytosolic calcium and protein kinase C are well-established mediators of luteolytic actions of prostaglandin F2alpha (PGF2alpha). The objectives of…”
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