Search Results - "Bowden, D W"

The APOL1 Gene and Allograft Survival after Kidney Transplantation by Reeves‐Daniel, A. M., DePalma, J. A., Bleyer, A. J., Rocco, M. V., Murea, M., Adams, P. L., Langefeld, C. D., Bowden, D. W., Hicks, P. J., Stratta, R. J., Lin, J.‐J., Kiger, D. F., Gautreaux, M. D., Divers, J., Freedman, B. I.

“…Coding variants in the apolipoprotein L1 gene (APOL1) are strongly associated with nephropathy in African Americans (AAs). The effect of transplanting kidneys…”
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Adiponectin as a novel determinant of bone mineral density and visceral fat by Lenchik, L, Register, T.C, Hsu, F-C, Lohman, K, Nicklas, B.J, Freedman, B.I, Langefeld, C.D, Carr, J.J, Bowden, D.W

“…Growing evidence suggests that positive associations between fat mass (FM) and bone mineral density (BMD) are mediated by not only biomechanical but also…”
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C-reactive protein concentration predicts mortality in type 2 diabetes: the Diabetes Heart Study by Cox, A. J., Agarwal, S., M Herrington, D., Carr, J. J., Freedman, B. I., Bowden, D. W.

“…Diabet. Med. 29, 767–770 (2012) Aims  Although current American Heart Association guidelines address C‐reactive protein concentration and cardiovascular…”
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Implication of European-derived adiposity loci in African Americans by Hester, J M, Wing, M R, Li, J, Palmer, N D, Xu, J, Hicks, P J, Roh, B H, Norris, J M, Wagenknecht, L E, Langefeld, C D, Freedman, B I, Bowden, D W, Ng, M C Y

“…Objective: Recent genome-wide association studies (GWAS) have identified multiple novel loci associated with adiposity in European-derived study populations…”
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Analysis of FTO gene variants with obesity and glucose homeostasis measures in the multiethnic Insulin Resistance Atherosclerosis Study cohort by WIng, M.R, Ziegler, J.M, Langefeld, C.D, Roh, B.H, Palmer, N.D, Mayer-Davis, E.J, Rewers, M.J, Haffner, S.M, Wagenknecht, L.E, Bowden, D.W

“…Objective: Previous studies have replicated the association of variants within FTO (fat mass- and obesity-associated) intron 1 with obesity and adiposity…”
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Common genetic variants differentially influence the transition from clinically defined states of fasting glucose metabolism by Walford, G. A., Green, T., Neale, B., Isakova, T., Rotter, J. I., Grant, S. F. A., Fox, C. S., Pankow, J. S., Wilson, J. G., Meigs, J. B., Siscovick, D. S., Bowden, D. W., Daly, M. J., Florez, J. C.

“…Aims/hypothesis Common genetic variants have been associated with type 2 diabetes. We hypothesised that a subset of these variants may have different effects…”
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Psoas and Paraspinous Muscle Measurements on Computed Tomography Predict Mortality in European Americans with Type 2 Diabetes Mellitus by Tucker, B M, Hsu, F C, Register, T C, Xu, J, Smith, S C, Murea, M, Bowden, D W, Freedman, B I, Lenchik, L

“…Appendicular skeletal muscle mass index and muscle attenuation (density) are negatively associated with mortality in European-derived populations. The present…”
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The impact of ethnicity and sex on subclinical cardiovascular disease : the Diabetes Heart Study by FREEDMAN, B. I, HSU, F. C, LANGEFELD, C. D, RICH, S. S, HERRINGTON, D. M, CARR, J. J, XU, J, BOWDEN, D. W, WAGENKNECHT, L. E

“…African-Americans with type 2 diabetes and access to adequate healthcare are at lower risk of clinical coronary artery disease than are white diabetic…”
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Ethnic variation in the correlation between random serum glucose concentration and glycated haemoglobin by Bleyer, A. J., Hire, D., Russell, G. B., Xu, J., Divers, J., Shihabi, Z., Bowden, D. W., Freedman, B. I.

“…Aims  To determine if the relationship between serum glucose concentration and glycated haemoglobin is different between African‐Americans and whites. Methods …”
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genome-wide association scan for acute insulin response to glucose in Hispanic-Americans: the Insulin Resistance Atherosclerosis Family Study (IRAS FS) by Rich, S. S, Goodarzi, M. O, Palmer, N. D, Langefeld, C. D, Ziegler, J, Haffner, S. M, Bryer-Ash, M, Norris, J. M, Taylor, K. D, Haritunians, T, Rotter, J. I, Chen, Y.-D. I, Wagenknecht, L. E, Bowden, D. W, Bergman, R. N

“…Aims/hypothesis This study sought to identify genes and regions in the human genome that are associated with the acute insulin response to glucose (AIRg), an…”
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Genome-wide linkage scans for renal function and albuminuria in Type 2 diabetes mellitus: the Diabetes Heart Study by Freedman, B. I., Bowden, D. W., Rich, S. S., Xu, J., Wagenknecht, L. E., Ziegler, J., Hicks, P. J., Langefeld, C. D.

“…Aims/hypothesis  Glomerular filtration rate (GFR), end‐stage renal disease and albuminuria are highly heritable. We performed a genome‐wide linkage scan in 416…”
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Association of PNPLA3 SNP rs738409 with liver density in African Americans with type 2 diabetes mellitus by Cox, A.J, Wing, M.R, Carr, J.J, Hightower, R.C, Smith, S.C, Xu, J, Wagenknecht, L.E, Bowden, D.W, Freedman, B.I

“…Abstract Aim Non-alcoholic fatty liver disease (NAFLD) is commonly diagnosed in patients with obesity and type 2 diabetes mellitus (T2DM), and has been…”
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Candidate loci for insulin sensitivity and disposition index from a genome-wide association analysis of Hispanic participants in the Insulin Resistance Atherosclerosis (IRAS) Family Study by Palmer, N. D, Langefeld, C. D, Ziegler, J. T, Hsu, F, Haffner, S. M, Fingerlin, T, Norris, J. M, Chen, Y. I, Rich, S. S, Haritunians, T, Taylor, K. D, Bergman, R. N, Rotter, J. I, Bowden, D. W

“…Aims/hypothesis The majority of type 2 diabetes genome-wide association studies (GWAS) to date have been performed in European-derived populations and have…”
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Heterogeneity in gene loci associated with type 2 diabetes on human chromosome 20q13.1 by Bento, J.L., Palmer, N.D., Zhong, M., Roh, B., Lewis, J.P., Wing, M.R., Pandya, H., Freedman, B.I., Langefeld, C.D., Rich, S.S., Bowden, D.W., Mychaleckyj, J.C.

“…Human chromosome 20q12-q13.1 has been linked to type 2 diabetes mellitus (T2DM) in multiple studies. We screened a 5.795-Mb region for diabetes-related…”
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Increased intestinal permeability as a risk factor for type 2 diabetes by Cox, A.J, Zhang, P, Bowden, D.W, Devereaux, B, Davoren, P.M, Cripps, A.W, West, N.P

“…Abstract Aim Relationships between the intestinal microbiota, intestinal permeability and inflammation in the context of risk for obesity-associated disease…”
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Genetic Epidemiology of Subclinical Cardiovascular Disease in the Diabetes Heart Study by Bowden, D. W., Lehtinen, A. B., Ziegler, J. T., Rudock, M. E., Xu, J., Wagenknecht, L. E., Herrington, D. M., Rich, S. S., Freedman, B. I., Carr, J. J., Langefeld, C. D.

“…Summary A genome‐wide linkage scan of 357 European American (EA) and 72 African American (AA) pedigrees multiplex for type 2 diabetes mellitus (T2DM) was…”
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Mutations of the cathepsin C gene are responsible for Papillon-Lefèvre syndrome by Hart, Thomas C, Hart, P Suzanne, Bowden, Donald W, Michalec, Michael D, Callison, Scott A, Walker, Steve J, Zhang, Yingze, Firatli, Erhan

“…Papillon-Lefèvre syndrome (PLS) is an autosomal recessive disorder characterised by palmoplantar hyperkeratosis and severe early onset periodontitis that…”
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Association of adipose tissue deposition and beta-2 adrenergic receptor variants: the IRAS family study by LANGE, L. A, NORRIS, J. M, LANGEFELD, C. D, NICKLAS, B. J, WAGENKNECHT, L. E, SAAD, M. F, BOWDEN, D. W

“…Adipose tissue distribution (visceral vs subcutaneous) has been shown to be an important predictor of insulin resistance, diabetes and cardiovascular disease,…”
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Potential Donor–Recipient MYH9 Genotype Interactions in Posttransplant Nephrotic Syndrome After Pediatric Kidney Transplantation by Freedman, B. I., Nagaraj, S. K., Lin, J.‐J., Gautreaux, M. D., Bowden, D. W., Iskandar, S. S., Stratta, R. J., Rogers, J., Hartmann, E. L., Farney, A. C., Reeves‐Daniel, A. M.

“…Recurrence of focal segmental glomerulosclerosis (FSGS) with nephrotic syndrome is relatively common after kidney transplantation in young recipients whose…”
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Quantitative trait loci for abdominal fat and BMI in Hispanic-Americans and African-Americans: the IRAS Family Study by NORRIS, J. M, LANGEFELD, C. D, WAGENKNECHT, L. E, SCHERZINGER, A. L, RICH, S. S, BOOKMAN, E, BECK, S. R, SAAD, M. F, HAFFNER, S. M, BERGMAN, R. N, BOWDEN, D. W

“…To conduct linkage analysis for body mass index (BMI, kg/m2), waist-to-hip ratio (WHR), visceral adipose tissue mass (VAT, cm2) and subcutaneous adipose tissue…”
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