Search Results - "Bovio, Bruna"
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Three-dimensional heterocycles: new uracil-based structures obtained by nucleophilic substitution at the sp2 carbon of bromoisoxazoline
Published in Molecules (Basel, Switzerland) (24-06-2014)“…The regioisomeric cycloadducts of bromonitrile oxide and N-benzoyl-2,3-oxaza-norborn-5-ene were easily prepared and elaborated into a novel class of…”
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Ene Reaction of Nitrosocarbonyl Mesitylene with the Cinnamyl Alcohol: Metabolic Activity and Apoptosis of the Synthetized 6‑Chloropurine N,O-Nucleoside Analogues
Published in ACS omega (31-07-2018)“…Nitrosocarbonyl mesitylene intermediate undergoes an ene reaction with cinnamyl alcohol affording the corresponding 5-hydroxy-isoxazolidine in fair yields. The…”
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N,O‑Nucleosides from Ene Reactions of Nitrosocarbonyl Intermediates with the 3‑Methyl-2-buten-1-ol
Published in Journal of organic chemistry (18-01-2013)“…Nitrosocarbonyl intermediates undergo ene reactions with allylic alcohols, affording regioisomeric adducts in fair yields. Nitrosocarbonyl benzene reacts with…”
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4-Heterosubstituted Cyclopentenone Antiviral Compounds: Synthesis, Mechanism, and Antiviral Evaluation
Published in European journal of organic chemistry (01-02-2016)“…Racemic 4‐oxocyclopent‐2‐en‐1‐yl acetate was used in a short synthesis of nucleoside analogues with pyrimidine and purine heterobases. The protocol is based on…”
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Synthesis of novel anthracene derivatives of isoxazolino-carbocyclic nucleoside analogues
Published in Tetrahedron (04-02-2012)“…The synthesis of isoxazolino-carbocyclic nor-nucleosides incorporating an anthracene moiety was properly tuned through nitrosocarbonyl intermediates chemistry,…”
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Syntheses of New Carbanucleosides by Pericyclic Reactions
Published in European journal of organic chemistry (01-06-2013)“…The synthesis of heterobase‐functionalized cyclopentene derivatives as valuable substrate for the introduction of suitable substituents through pericyclic…”
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Synthesis and molecular modeling of novel dihydroxycyclopentane-carbonitrile nor-nucleosides by bromonitrile oxide 1,3-dipolar cycloaddition
Published in Tetrahedron (18-02-2012)“…The regioisomeric cycloadducts of the bromonitrile oxide to the N-benzoyl-2,3-oxazanorborn-5-ene were easily prepared and elaborated into a novel class of…”
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1,2,4-Oxadiazole 4-Oxides as Nitrones in 1,3-Dipolar Cycloaddition Reactions to Vinyl Ethers
Published in European Journal of Organic Chemistry (01-03-2012)“…1,2,4‐Oxadiazole 4‐oxides display nitronic reactivity and selectivities identical to those of N‐methyl‐C‐phenyl nitrone, which is a typical acyclic nitrone,…”
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Book Review Journal Article -
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RuO sub(4-catalyzed oxidation reactions of isoxazolino-2-azanorbornane derivatives: a short-cut synthesis of tricyclic lactams and peptidomimetic gamma -amino acids)
Published in Tetrahedron (11-03-2011)“…A rapid access to peptidomimetic conformationally constrained gamma -amino acids has been developed through the efficient RuO sub(4-mediated oxidation of…”
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RuO 4-catalyzed oxidation reactions of isoxazolino-2-azanorbornane derivatives: a short-cut synthesis of tricyclic lactams and peptidomimetic γ-amino acids
Published in Tetrahedron (2011)“…A rapid access to peptidomimetic conformationally constrained γ-amino acids has been developed through the efficient RuO 4-mediated oxidation of regioisomeric…”
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Paralipomena of the Isoxazoline Carbocyclic Nucleoside Analogs
Published in ChemistrySelect (Weinheim) (16-05-2016)“…The synthetic pathway towards silyl‐substituted nucleoside analogs is presented and relies upon the 1,3‐dipolar cycloaddition of in situ generated nitrile…”
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A Fluorine 1,2-Migration via Aryl Cation/Radical/Radical Anion/Radical Sequence
Published in Organic letters (02-08-2013)“…Irradiation of a 7-piperazino-8-fluoroquinolone causes formal 1,2-fluorine migration, piperazine loss and reduction, or nucleophile addition in 8. Product…”
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Conversion of a nitrosocarbonyl hetero Diels–Alder cycloadduct to useful isoxazoline-carbocyclic aminols
Published in Tetrahedron (19-12-2009)“…A new approach to useful precursors for the synthesis of isoxazoline-carbocyclic nucleosides is detailed, starting from the readily available…”
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Structure Determination of 8-Benzyl-5-phenyl-3-oxa-4,8-diaza-tricyclo[5.2.1.02,6]dec-4-ene and 1-(9-Ethoxy-5-phenyl-3-oxa-4,8-diaza-tricyclo[5.2.1.02,6]dec-4-en-8-yl)-ethanone: Their Synthesis, Chemical Relationship and Comparison with Similar Compounds
Published in Journal of chemical crystallography (2012)“…The molecular and crystal structures of 8-benzyl-5-phenyl-3-oxa-4,8-diaza-tricyclo[5.2.1.0 2,6 ]dec-4-ene 11a and…”
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A Straightforward Synthesis of Isoxazoline-Based Carbocyclic Nucleosides from 1,3-Cyclohexadiene through Nitrosocarbonyl Chemistry
Published in European Journal of Organic Chemistry (01-12-2007)“…3‐Benzoyl‐2‐oxa‐3‐azabicyclo[2.2.2]oct‐5‐ene undergoes cycloaddition with benzonitrile oxide to afford a mixture of syn and anti regioisomeric cycloadducts…”
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Book Review Journal Article -
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Isoxazoline-carbocyclic aminols for nucleoside synthesis through aza-Diels–Alder reactions
Published in Tetrahedron (31-07-2006)“…A novel approach to useful aminols for the synthesis of carbocyclic nucleosides is reported starting from a convenient source, the 2-azanorborn-5-enes. These…”
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Crystal structure of 1-(2-azidophenyl)-3, 5-dimethylpyrazole, C 11 H 11 N 5
Published in Journal of chemical crystallography (01-10-2004)Get full text
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Crystal structure and DFT calculations of 3,8-diphenyl-3a,4,5,5a,8a,8b-hexahydro-benzo[1,2-d: 3,4-d′]diisoxazole, C 20H 18N 2O 2
Published in Journal of molecular structure (2005)“…The molecular and crystal structures of 3,8-diphenyl-3a,4,5,5a,8a,8b-hexahydro-benzo[1,2-d: 3,4-d′]diisoxazole have been XRD determined. The compound…”
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