Search Results - "Bovinder Ylitalo, Erik"

Expression of androgen receptor splice variants in prostate cancer bone metastases is associated with castration-resistance and short survival by Hörnberg, Emma, Ylitalo, Erik Bovinder, Crnalic, Sead, Antti, Henrik, Stattin, Pär, Widmark, Anders, Bergh, Anders, Wikström, Pernilla

“…Constitutively active androgen receptor variants (AR-V) lacking the ligand binding domain (LBD) may promote the development of castration-resistant prostate…”
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KLK4T2 Is a Hormonally Regulated Transcript from the KLK4 Locus by Lundwall, Åke, Ylitalo, Erik Bovinder, Wikström, Pernilla, Brattsand, Maria

“…The human kallikrein-related peptidase 4 (KLK4) and the transcribed pseudogene KLKP1 are reported to be highly expressed in the prostate. When trying to clone…”
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Characterization of prostate cancer bone metastases according to expression levels of steroidogenic enzymes and androgen receptor splice variants by Jernberg, Emma, Thysell, Elin, Bovinder Ylitalo, Erik, Rudolfsson, Stina, Crnalic, Sead, Widmark, Anders, Bergh, Anders, Wikström, Pernilla

“…Intra-tumoral steroidogenesis and constitutive androgen receptor (AR) activity have been associated with castration-resistant prostate cancer (CRPC). This…”
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Epidemiology and ecology of the sylvatic cycle of African Swine Fever Virus in Kenya by Obanda, Vincent, Akinyi, Mercy, King'ori, Edward, Nyakundi, Ruth, Ochola, Griphin, Oreng, Purity, Mugambi, Kevin, Waiguchu, Grace Mwihaki, Chege, Mary, Rosenbaum, William, Ylitalo, Erik Bovinder, Bäck, Anne Tuiskunen, Pettersson, Lisa, Mukunzi, Opanda Silvanos, Agwanda, Bernard, Stenberg-Lewerin, Susanna, Lwande, Olivia Wesula

“…•Detection of African Swine Fever Virus (ASFV) in Ornithodoros porcinus in Kenya.•Ornithodoros porcinus is a vector of Genotype IX ASFV.•Common warthogs have a…”
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Marked response to cabazitaxel in prostate cancer xenografts expressing androgen receptor variant 7 and reversion of acquired resistance by anti‐androgens by Ylitalo, Erik Bovinder, Thysell, Elin, Thellenberg‐Karlsson, Camilla, Lundholm, Marie, Widmark, Anders, Bergh, Anders, Josefsson, Andreas, Brattsand, Maria, Wikström, Pernilla

“…Background Taxane treatment may be a suitable therapeutic option for patients with castration‐resistant prostate cancer and high expression of constitutively…”
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Bone Cell Activity in Clinical Prostate Cancer Bone Metastasis and Its Inverse Relation to Tumor Cell Androgen Receptor Activity by Nordstrand, Annika, Bovinder Ylitalo, Erik, Thysell, Elin, Jernberg, Emma, Crnalic, Sead, Widmark, Anders, Bergh, Anders, Lerner, Ulf H, Wikström, Pernilla

“…Advanced prostate cancer frequently metastasizes to bone and induces a mixed osteoblastic/osteolytic bone response. Standard treatment for metastatic prostate…”
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Gene expression profiles define molecular subtypes of prostate cancer bone metastases with different outcomes and morphology traceable back to the primary tumor by Thysell, Elin, Vidman, Linda, Ylitalo, Erik Bovinder, Jernberg, Emma, Crnalic, Sead, Iglesias‐Gato, Diego, Flores‐Morales, Amilcar, Stattin, Pär, Egevad, Lars, Widmark, Anders, Rydén, Patrik, Bergh, Anders, Wikström, Pernilla

“…Bone metastasis is the lethal end‐stage of prostate cancer (PC), but the biology of bone metastases is poorly understood. The overall aim of this study was…”
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Subgroups of Castration-resistant Prostate Cancer Bone Metastases Defined Through an Inverse Relationship Between Androgen Receptor Activity and Immune Response by Ylitalo, Erik Bovinder, Thysell, Elin, Jernberg, Emma, Lundholm, Marie, Crnalic, Sead, Egevad, Lars, Stattin, Pär, Widmark, Anders, Bergh, Anders, Wikström, Pernilla

“…Abstract Background Novel therapies for men with castration-resistant prostate cancer (CRPC) are needed, particularly for cancers not driven by androgen…”
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Hybrid capture-based next-generation sequencing of new and old world Orthohantavirus strains and wild-type Puumala isolates from humans and bank voles by Rosenbaum, William, Bovinder Ylitalo, Erik, Castel, Guillaume, Sjödin, Andreas, Larsson, Pär, Wigren Byström, Julia, Forsell, Mattias N.E., Ahlm, Clas, Pettersson, Lisa, Tuiskunen Bäck, Anne

“…•Genomic characterization of viruses is essential to understand their pathophysiology.•We have designed a targeted hybrid-capture panel encompassing all…”
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A novel DNA methylation signature is associated with androgen receptor activity and patient prognosis in bone metastatic prostate cancer by Ylitalo, Erik Bovinder, Thysell, Elin, Landfors, Mattias, Brattsand, Maria, Jernberg, Emma, Crnalic, Sead, Widmark, Anders, Hultdin, Magnus, Bergh, Anders, Degerman, Sofie, Wikström, Pernilla

“…Patients with metastatic prostate cancer (PC) are treated with androgen deprivation therapy (ADT) that initially reduces metastasis growth, but after some time…”
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A Systems Approach to Prostate Cancer Classification-Letter by Thysell, Elin, Ylitalo, Erik Bovinder, Jernberg, Emma, Bergh, Anders, Wikström, Pernilla

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Investigating microRNA Profiles in Prostate Cancer Bone Metastases and Functional Effects of microRNA-23c and microRNA-4328 by Järemo, Helena, Semenas, Julius, Bergström, Sofia Halin, Lundholm, Marie, Thysell, Elin, Widmark, Anders, Crnalic, Sead, Ylitalo, Erik Bovinder, Bergh, Anders, Brattsand, Maria, Wikström, Pernilla

“…MicroRNAs (miRNAs) are aberrantly expressed in prostate cancer (PC), but comprehensive knowledge about their levels and function in metastatic PC is lacking…”
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Inhibition of the insulin-like growth factor-1 receptor potentiates acute effects of castration in a rat model for prostate cancer growth in bone by Nordstrand, Annika, Bergström, Sofia Halin, Thysell, Elin, Bovinder-Ylitalo, Erik, Lerner, Ulf H., Widmark, Anders, Bergh, Anders, Wikström, Pernilla

“…Prostate cancer (PCa) patients with bone metastases are primarily treated with androgen deprivation therapy (ADT). Less pronounced ADT effects are seen in…”
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Abstract 1332: Extracted mRNA from frozen buffy coat samples shows promise for use in downstream sequencing analyses by Ylitalo, Erik Bovinder, Vidman, Linda, Harlid, Sophia, Van Guelpen, Bethany

“…Frozen blood samples are routinely collected and stored in medical biobanks across the world, often for periods of several decades, and later used for medical…”
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Clinically relevant molecular subgroups of prostate cancer bone metastases by Thysell, Elin, Bovinder Ylitalo, Erik, Jernberg, Emma, Crnalic, Sead, Widmark, Anders, Bergh, Anders, Wikström, Pernilla

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Abstract A048: Bone remodeling in relation to androgen receptor activity in prostate cancer bone metastases by Ylitalo, Erik Bovinder, Nordstrand, Annika, Thysell, Elin, Jernberg, Emma, Crnalic, Sead, Widmark, Anders, Bergh, Anders, Lerner, Ulf H., Wikström, Pernilla

“…Prostate cancer often metastasizes to bone and the metastases are generally classified as osteoblastic, although a mixed osteoblastic/osteolytic bone response…”
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Bone remodeling in relation to androgen receptor activity in prostate cancer bone metastases by Bovinder Ylitalo, Erik, Nordstrand, Annika, Thysell, Elin, Jernberg, Emma, Crnalic, Sead, Widmark, Anders, Bergh, Anders, Lerner, Ulf H., Wikström, Pernilla

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Addendum to “Subgroups of Castration-resistant Prostate Cancer Bone Metastases Defined Through an Inverse Relationship Between Androgen Receptor Activity and Immune Response” [Eur Urol 2017;71:776–87] by Ylitalo, Erik Bovinder, Thysell, Elin, Jernberg, Emma, Lundholm, Marie, Crnalic, Sead, Egevad, Lars, Stattin, Pär, Widmark, Anders, Bergh, Anders, Wikström, Pernilla

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Subgroups of Castration-resistant Prostate Cancer Bone Metastases Defined Through an Inverse Relationship Between Androgen Receptor Activity and Immune Response (vol 71, pg 776, 2017) by Ylitalo, EB, Thysell, E, Jernberg, E, Lundholm, M, Crnalic, S, Egevad, L, Stattin, P, Widmark, A, Bergh, A, Wikstrom, P

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