Search Results - "Bovell, Douglas L."

The evolution of eccrine sweat gland research towards developing a model for human sweat gland function by Bovell, Douglas L.

“…For several decades now, researchers, professional bodies, governments, and journals such as the journal of Experimental Dermatology have worked to reduce the…”
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Latherin: A Surfactant Protein of Horse Sweat and Saliva by McDonald, Rhona E, Fleming, Rachel I, Beeley, John G, Bovell, Douglas L, Lu, Jian R, Zhao, Xiubo, Cooper, Alan, Kennedy, Malcolm W

“…Horses are unusual in producing protein-rich sweat for thermoregulation, a major component of which is latherin, a highly surface-active, non-glycosylated…”
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PAR-2 receptor-induced effects on human eccrine sweat gland cells by Bovell, Douglas L, Kofler, Barbara, Lang, Roland

“…Serine proteases can induce cell signaling by stimulating G-protein-coupled receptors, called proteinase-activated receptors (PAR’s) on a variety of epithelial…”
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Activation of chloride secretion via proteinase-activated receptor 2 in a human eccrine sweat gland cell line - NCL-SG3 by Bovell, Douglas L., Santic, Radmila, Kofler, Barbara, Hermann, Anton, Wilson, Darius, Corbett, Alistair, Lang, Roland

“…:  Proteinase‐activated receptor 2 (PAR‐2) has been shown to elicit secretion in a variety of secretory epithelial cells by the transepithelial movement of…”
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Galanin is a modulator of eccrine sweat gland secretion by Bovell, Douglas L., Holub, Barbara S., Odusanwo, Olutayo, Brodowicz, Bernhard, Rauch, Isabella, Kofler, Barbara, Lang, Roland

“…The neuropeptide galanin has been ascribed different roles in modulating physiological functions in the skin. The present study examined the function of…”
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The secretory clear cell of the eccrine sweat gland as the probable source of excess sweat production in hyperhidrosis by Bovell, Douglas L., MacDonald, Alison, Meyer, Barbara A., Corbett, Alistair D., MacLaren, William M., Holmes, Susan L., Harker, Mark

“…:  Primary hyperhidrosis is characterized by excessive sweating in palmar, plantar and axillary body regions. Gland hypertrophy and the existence of a third…”
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Evidence of purinergic neurotransmission in isolated, intact horse sweat glands by Bovell, Douglas L., Riggs, Christopher M., Sidlow, Gordon, Troester, Suzanne, MacLaren, William, Yip, Wallace, Ko, Wing H.

“…Background Fluid secretion by sweat glands in response to heat and exercise is underpinned by increases in intracellular calcium. In horses, this is primarily…”
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Equine sweating and anhidrosis Part 1 - equine sweating by Jenkinson, David McEwan, Elder, Hugh Y, Bovell, Douglas L

“…Sweating has a variety of functions in mammals including pheromone action, excretion of waste products and maintenance of the skin surface ecosystem. In a…”
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Equine sweating and anhidrosis
Part 2: anhidrosis by Jenkinson, David McEwan, Elder, Hugh Y., Bovell, Douglas L.

“…The condition of anhidrosis is described in this review, and the latest theories on the causal factors are explored. The evidence supports the hypothesis that…”
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A preliminary study of the short circuit current (Isc) responses of sweat gland cells from normal and anhidrotic horses to purinergic and adrenergic agonists by Wilson, Darius C. S., Corbett, Alistair D., Steel, Cate, Pannirselvam, Roshni, Bovell, Douglas L.

“…The causal factors of equine anhidrosis have not yet been elucidated but defective electrolyte transport mechanisms in the gland are likely to be involved. To…”
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Immunolocalization of aquaporin-5 expression in sweat gland cells from normal and anhidrotic horses by BOVELL, DOUGLAS L., LINDSAY, SUSAN L., CORBETT, ALISTAIR D., STEEL, CATHERINE

“…Western blot analysis showed that sweat gland cells from freely sweating horses expressed the water channel aquaporin‐5 (AQP‐5). Immunohistochemistry revealed…”
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Extracellular ATP can activate autonomic signal transduction pathways in cultured equine sweat gland epithelial cells by WING HUNG KO, O'DOWD, J. J. M, PEDIANI, J. D, BOVELL, D. L, ELDER, H. Y, MCEWAN JENKINSON, D, WILSON, S. M

“…Changes in intracellular free calcium concentration ([Ca2+]i) were monitored in a cell line that was derived from the equine sweat gland epithelium. ATP and…”
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PAR‐2 receptor‐induced intracellular signalling in isolated intact human eccrine sweat gland cells and primary tissue culture cells by Bovell, Douglas L., Corbett, Alistair D., Lang, Roland

“…Abstract only PAR‐2 receptors can evoke intracellular signalling and anion transport in a cell line derived from human sweat glands, however, it is unknown…”
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The secretory clear cell of the eccrine sweat gland as the probable source of excess sweat production in hyperhidrosis: Letter to the Editor by Bovell, Douglas L., MacDonald, Alison, Meyer, Barbara A., Corbett, Alistair D., MacLaren, William M., Holmes, Susan L., Harker, Mark

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The control of potassium (86Rb+) efflux in the isolated human sweat gland by Bovell, D L, Elder, H Y, Jenkinson, D M, Wilson, S M

“…Sweat glands, isolated from strips of human skin and pre-loaded with 86Rb+, a marker of potassium transport, were superfused with physiological saline and rate…”
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Equine sweating and anhidrosisPart 2: anhidrosis by Jenkinson, David McEwan, Elder, Hugh Y., Bovell, Douglas L.

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Nucleotide-evoked ion transport and [Ca 2+] i changes in normal and hyperhidrotic human sweat gland cells by Bovell, Douglas L, Clunes, Mark T, Elder, Hugh Y, Wong, Connie H.Y, Ko, Wing H

“…Apical and basolateral application of ATP and UTP evoked [Ca 2+] i and short circuit current (Isc) increases in normal and hyperhidrotic human eccrine sweat…”
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Nucleotide-evoked ion transport and [Ca(2+)](i) changes in normal and hyperhidrotic human sweat gland cells by Bovell, D L, Clunes, M T, Elder, H Y, Wong, C H, Ko, W H

“…Apical and basolateral application of ATP and UTP evoked [Ca(2+)](i) and short circuit current (Isc) increases in normal and hyperhidrotic human eccrine sweat…”
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Ionic Mechanisms Involved in the Secretion of Sweat by Bovell, Douglas L

“…Previous EPXMA studies on sweat glands from the horse and the human demonstrated that a fall in the intracellular concentration of K+ occurs in response to…”
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Ionic Mechanisms Involved in the Secretion of Sweat by Bovell, Douglas L

“…Previous EPXMA studies on sweat glands from the horse and the human demonstrated that a fall in the intracellular concentration of K+ occurs in response to…”
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