Search Results - "Bove, Susan E"

Evaluation of TrkB and BDNF transcripts in prefrontal cortex, hippocampus, and striatum from subjects with schizophrenia, bipolar disorder, and major depressive disorder by Reinhart, Veronica, Bove, Susan E, Volfson, Dmitri, Lewis, David A, Kleiman, Robin J, Lanz, Thomas A

“…Abstract Brain-derived neurotrophic factor (BDNF) signaling is integral to a range of neural functions, including synaptic plasticity and exhibits…”
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Chronic suppression of phosphodiesterase 10A alters striatal expression of genes responsible for neurotransmitter synthesis, neurotransmission, and signaling pathways implicated in Huntington's disease by Kleiman, Robin J, Kimmel, Lida H, Bove, Susan E, Lanz, Thomas A, Harms, John F, Romegialli, Alison, Miller, Kenneth S, Willis, Amy, des Etages, Shelley, Kuhn, Max, Schmidt, Christopher J

“…Inhibition of phosphodiesterase 10A (PDE10A) promotes cyclic nucleotide signaling, increases striatal activation, and decreases behavioral activity. Enhanced…”
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Postmortem transcriptional profiling reveals widespread increase in inflammation in schizophrenia: a comparison of prefrontal cortex, striatum, and hippocampus among matched tetrads of controls with subjects diagnosed with schizophrenia, bipolar or major depressive disorder by Lanz, Thomas A., Reinhart, Veronica, Sheehan, Mark J., Rizzo, Stacey J. Sukoff, Bove, Susan E., James, Larry C., Volfson, Dmitri, Lewis, David A., Kleiman, Robin J.

“…Psychiatric disorders such as schizophrenia (SCZ), bipolar disorder (BD), and major depressive disorder (MDD) arise from complex interactions between genetic…”
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Use of a portable thermal imaging unit as a rapid, quantitative method of evaluating inflammation and experimental arthritis by Sanchez, Brian M., Lesch, Mark, Brammer, David, Bove, Susan E., Thiel, Melissa, Kilgore, Kenneth S.

“…Thermal imaging has been utilized, both preclinically and clinically, as a tool for assessing inflammation and arthritis. However, previous studies have…”
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Robust changes in expression of brain-derived neurotrophic factor (BDNF) mRNA and protein across the brain do not translate to detectable changes in BDNF levels in CSF or plasma by Lanz, Thomas A., Bove, Susan E., Pilsmaker, Catherine D., Mariga, Abigail, Drummond, Elena M., Cadelina, Gregory W., Adamowicz, Wendy O., Swetter, Brentt J., Carmel, Sharon, Dumin, Jo Ann, Kleiman, Robin J.

“…Adult rats were treated acutely with peripheral kainic acid (KA), and changes in brain-derived neurotrophic factor (BDNF) mRNA and protein were tracked over…”
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Synthesis and SAR of 2-aryl pyrido[2,3- d]pyrimidines as potent mGlu5 receptor antagonists by Wendt, John A., Deeter, Susan D., Bove, Susan E., Knauer, Christopher S., Brooker, Rachel M., Augelli-Szafran, Corinne E., Schwarz, Roy D., Kinsora, Jack J., Kilgore, Kenneth S.

“…A novel series of potent 2-aryl pyrido[2,3- d]pyrimidine mGlu5 receptor antagonists are described. The synthesis and pharmacological activities of these…”
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Macrophage Migration Inhibitory Factor in the Bovine Corpus Luteum: Characterization of Steady-State Messenger Ribonucleic Acid and Immunohistochemical Localization1 by Bove, Susan E, Petroff, Margaret G, Nishibori, Masahiro, Pate, Joy L

“…Macrophage migration inhibitory factor (MIF) is a pro-inflammatory cytokine produced by T cells and macrophages. A number of tissues also produce MIF during…”
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New advances in musculoskeletal pain by Bove, Susan E, Flatters, Sarah J.L, Inglis, Julia J, Mantyh, Patrick W

“…Abstract Non-malignant musculoskeletal pain is the most common clinical symptom that causes patients to seek medical attention and is a major cause of…”
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Synthesis and SAR comparison of regioisomeric aryl naphthyridines as potent mGlu5 receptor antagonists by Galatsis, Paul, Yamagata, Koji, Wendt, John A., Connolly, Cleo J., Mickelson, John W., Milbank, Jared B.J., Bove, Susan E., Knauer, Christopher S., Brooker, Rachel M., Augelli-Szafran, Corinne E., Schwarz, Roy D., Kinsora, Jack J., Kilgore, Kenneth S.

“…We describe three novel regioisomeric series of aryl naphthyridine analogs, which are potent antagonists of the Class III GPCR mGlu5 receptor. The synthesis…”
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Dendritic spine density deficits in the hippocampal CA1 region of young Tg2576 mice are ameliorated with the PDE9A inhibitor PF-04447943 by Kleiman, Robin J, Lanz, Thomas A, Finley, James E, Bove, Susan E, Majchrzak, Mark J, Becker, Stacey L, Carvajal-Gonzales, Santos, Kuhn, A. Max, Wood, Kathleen M, Mariga, Abigail, Nelson, Frederick R, Verhoest, Patrick R, Seymour, Patricia A, Stephenson, Diane T

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Macrophage migration inhibitory factor in the bovine corpus luteum: characterization of steady-state messenger ribonucleic acid and immunohistochemical localization by Bove, S.E, Petroff, M.G, Nishibori, M, Pate, J.L

“…Macrophage migration inhibitory factor (MIF) is a pro-inflammatory cytokine produced by T cells and macrophages. A number of tissues also produce MIF during…”
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Estrogen withdrawal Induces Macrophage Invasion in the Rabbit Corpus Luteum1 by Naftalin, Dorit M., Bove, Susan E., Landis Keyes, P., Townson, David H.

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In vivo micro computed tomography of subchondral bone in the rat after intra-articular administration of monosodium iodoacetate by Morenko, B.J, Bove, S.E, Chen, L, Guzman, R.E, Juneau, P, Bocan, T.M.A, Peter, G.K, Arora, R, Kilgore, K.S

“…Osteoarthritis (OA) is a degenerative disease that is characterized by joint discomfort, loss of articular cartilage, and changes to the subchondral bone…”
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P3‐380: Dendritic spine density deficits in the hippocampal CA1 region of young Tg2576 mice are ameliorated with the PDE9A inhibitor PF‐04447943 by Kleiman, Robin J., Lanz, Thomas A., Finley, James E., Bove, Susan E., Majchrzak, Mark J., Becker, Stacey L., Carvajal-Gonzales, Santos, Kuhn, A. Max, Wood, Kathleen M., Mariga, Abigail, Nelson, Frederick R., Verhoest, Patrick R., Seymour, Patricia A., Stephenson, Diane T.

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Estrogen withdrawal induces macrophage invasion in the rabbit corpus luteum by NAFTALIN, D. M, BOVE, S. E, KEYES, P. L, TOWNSON, D. H

“…Macrophages within the corpus luteum are associated with spontaneous luteal regression in a number of species. However, an understanding of the consequences of…”
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