Search Results - "Bova, Sergio"
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Manipulation of Mitochondria Dynamics Reveals Separate Roles for Form and Function in Mitochondria Distribution
Published in Cell reports (Cambridge) (08-05-2018)“…Mitochondria shape is controlled by membrane fusion and fission mediated by mitofusins, Opa1, and Drp1, whereas mitochondrial motility relies on microtubule…”
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2
Numerical investigation of the seakeeping behavior of a catamaran advancing in regular head waves
Published in Ocean engineering (01-11-2011)“…A numerical study was undertaken in order to assess the capability of an unsteady RANS code to predict the seakeeping characteristics of a high-speed…”
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3
Techno-Economic Analysis of Biofuel, Solar and Wind Multi-Source Small-Scale CHP Systems
Published in Energies (Basel) (01-06-2020)“…The aim of the paper is the techno-economic analysis of innovative integrated combined heat and power (CHP) systems for the exploitation of different renewable…”
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4
Linear Model of a Turboshaft Aero-Engine Including Components Degradation for Control-Oriented Applications
Published in Energies (Basel) (01-03-2023)“…The engine fuel control system plays a crucial role in engine performance and fuel economy. Fuel control, in traditional engine control systems, is carried out…”
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Energetic, Economic and Environmental Performance Analysis of a Micro-Combined Cooling, Heating and Power (CCHP) System Based on Biomass Gasification
Published in Energies (Basel) (01-10-2023)“…In this paper, the performance of an innovative micro-combined cooling, heating, and power (CCHP) system, based on an internal combustion engine fueled with…”
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6
Flow-field and wake analysis of novel double-rotor open-center tidal current turbine by CFD simulations
Published in Ocean engineering (15-02-2021)“…Tidal turbines represent a new frontier for extracting energy from a huge potential of renewable source such as the tides. Despite the technology being mature…”
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7
Application of a Model-Based Controller for Improving Internal Combustion Engines Fuel Economy
Published in Energies (Basel) (01-03-2020)“…Improvements in internal combustion engine efficiency can be achieved with proper thermal management. In this work, a simulation tool for the preliminary…”
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8
Dynamic constriction and fission of endoplasmic reticulum membranes by reticulon
Published in Nature communications (22-11-2019)“…The endoplasmic reticulum (ER) is a continuous cell-wide membrane network. Network formation has been associated with proteins producing membrane curvature and…”
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New Therapeutic Applications of Phosphodiesterase 5 Inhibitors (PDE5-Is)
Published in Current medicinal chemistry (01-05-2016)“…Phosphodiesterase 5 inhibitors (PDE5-Is) sildenafil, vardenafil, tadalafil and the recently approved avanafil represent the first-line choice for both…”
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10
The Enigma of Norbormide, a Rattus -Selective Toxicant
Published in Cells (Basel, Switzerland) (06-05-2024)“…Norbormide (NRB) is a -selective toxicant, which was serendipitously discovered in 1964 and formerly marketed as an eco-friendly rodenticide that was deemed…”
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Live applications of norbormide-based fluorescent probes in Drosophila melanogaster
Published in PloS one (08-04-2019)“…In this study we investigated the performance of two norbormide (NRB)-derived fluorescent probes, NRBMC009 (green) and NRBZLW0047 (red), on dissected, living…”
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12
Differential effect of liver cirrhosis on the pregnane X receptor-mediated induction of CYP3A1 and 3A2 in the rat
Published in Drug metabolism and disposition (01-10-2014)“…Conflicting results have been obtained by clinical studies investigating the effect of liver cirrhosis on enzyme induction. Because ethical concerns do not…”
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The Selective Rat Toxicant Norbormide Blocks KATP Channels in Smooth Muscle Cells But Not in Insulin-Secreting Cells
Published in Frontiers in pharmacology (23-05-2019)“…Norbormide is a toxicant selective for rats to which it induces a widespread vasoconstriction. In a recent paper, we hypothesized a role of ATP-sensitive…”
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14
Congenital deafness and sinoatrial node dysfunction in mice lacking class D L-type Ca2+ channels
Published in Cell (07-07-2000)“…Voltage-gated L-type Ca2+ channels (LTCCs) containing a pore-forming alpha1D subunit (D-LTCCs) are expressed in neurons and neuroendocrine cells. Their…”
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Synthesis and Biological Characterization of a New Norbormide Derived Bodipy FL-Conjugated Fluorescent Probe for Cell Imaging
Published in Frontiers in pharmacology (25-09-2018)“…Norbormide (NRB) is a selective rat toxicant endowed with vasoconstrictor activity confined to the rat peripheral arteries. In a recent work we used a…”
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16
Expression and distribution of the adrenomedullin system in newborn human thymus
Published in PloS one (15-05-2014)“…Adrenomedullin (AM) is a multifunctional peptide endowed with various biological actions mediated by the interaction with the calcitonin receptor-like receptor…”
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Severe liver cirrhosis markedly reduces AhR-mediated induction of cytochrome P450 in rats by decreasing the transcription of target genes
Published in PloS one (23-04-2013)“…Although the induction of cytochrome P450 (CYP) has long been investigated in patients with cirrhosis, the question whether liver dysfunction impairs the…”
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An NBD Derivative of the Selective Rat Toxicant Norbormide as a New Probe for Living Cell Imaging
Published in Frontiers in pharmacology (23-09-2016)“…Norbormide (NRB) is a unique compound that acts directly on rat vascular myocytes to trigger a contractile process, through an as yet unknown mechanism, which…”
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Species-specific modulation of the mitochondrial permeability transition by norbormide
Published in Biochimica et biophysica acta (30-06-2005)“…In the present study, we show that norbormide stimulates the opening of the permeability transition pore (PTP) in mitochondria from various organs of the rat…”
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Latching control of a point-absorber wave energy converter with a hydraulic power take-off system: A calabrian case study
Published in Ocean engineering (15-10-2024)“…Wave energy converters represent a promising renewable energy technology; however, they are still widely untapped worldwide, especially in Italy. In this…”
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