Search Results - "Bouzian, Younos"

Crystal structure, DFT study and Hirshfeld surface analysis of ethyl 6-chloro-2-ethoxyquinoline-4-carboxylate by Bouzian, Younos, Karrouchi, Khalid, Anouar, El Hassane, Bouhfid, Rachid, Arshad, Suhana, Essassi, El Mokhtar

“…In the title quinoline derivative, C 14 H 14 ClNO 3 , there is an intramolecular C—H...O hydrogen bond forming an S (6) graph-set motif. The molecule is…”
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Crystal structure, Hirshfeld surface analysis and density functional theory study of benzyl 2-oxo-1-(prop-2-yn-1-yl)-1,2-dihydroquinoline-4-carboxylate by Bouzian, Younos, Chkirate, Karim, Mague, Joel T., Al-Ostoot, Fares Hezam, Hammou Ahabchane, Noureddine, Essassi, El Mokhtar

“…The title molecule, C 20 H 15 NO 3 , adopts a Z -shaped conformation with the carboxyl group nearly coplanar with the dihydroquinoline unit. In the crystal,…”
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Crystal structure and Hirshfeld surface analysis of hexyl 1-hexyl-2-oxo-1,2-dihydroquinoline-4-carboxylate by Bouzian, Younos, Kansiz, Sevgi, Mahi, Lhassane, Ahabchane, Noureddine Hamou, Mague, Joel T., Dege, Necmi, Karrouchi, Khalid, Essassi, El Mokhtar

“…The asymmetric unit of the title compound, C 22 H 31 NO 3 , comprises of one molecule. The molecule is not planar, with the carboxylate ester group inclined by…”
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Crystal structure and DFT study of benzyl 1-benzyl-2-oxo-1,2-dihydroquinoline-4-carboxylate by Bouzian, Younos, Faizi, Md. Serajul Haque, Mague, Joel T., Otmani, Bouchaib El, Dege, Necmi, Karrouchi, Khalid, Essassi, El Mokhtar

“…In the title quinoline derivative, C 24 H 19 NO 3 , the two benzyl rings are inclined to the quinoline ring mean plane by 74.09 (8) and 89.43 (7)°, and to each…”
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Synthesis, spectroscopic characterization, crystal structure, DFT, molecular docking and in vitro antibacterial potential of novel quinoline derivatives by Bouzian, Younos, Karrouchi, Khalid, Sert, Yusuf, Lai, Chin-Hung, Mahi, Lhassane, Ahabchane, Noureddine Hamou, Talbaoui, Ahmed, Mague, Joel T., Essassi, El Mokhtar

“…Two novel quinolone derivatives were prepared and characterized using different spectroscopic techniques and single crystal X-ray diffraction. The DFT-B3LYP…”
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Design and evaluation of novel inhibitors for the treatment of clear cell renal cell carcinoma by Bouzian, Younos, El Hafi, Mohamed, Parvizi, Negar, Kim, Woonghee, Subaşioğlu, Mine, Ozcan, Mehmet, Turkez, Hasan, Mardinoglu, Adil

“…[Display omitted] •Conventional chemotherapies have limited efficacy in treating clear cell renal cell carcinoma (ccRCC) due to its high molecular diversity,…”
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Synthesis, spectroscopic characterization, DFT, molecular docking and in vitro antibacterial potential of novel quinoline derivatives by Bouzian, Younos, Sert, Yusuf, Khalid, Karrouchi, Van Meervelt, Luc, Chkirate, Karim, Mahi, Lhassane, Ahabchane, Noureddine Hamou, Talbaoui, Ahmed, Essassi, El Mokhtar

“…•Three novel quinoline derivatives were synthesized and characterized by FT-IR, 1H NMR, 13C NMR and single-crystal XRD.•DFT calculations were…”
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Ethyl 2-{[2-(2-ethoxy-2-oxoethoxy)quinolin-4-yl]carbonyloxy}acetate by Bouzian, Younos, Hlimi, Fouzia, Sebbar, Nada kheira, El Hafi, Mohamed, Hni, Brahim, Essassi, El Mokhtar, Mague, Joel T.

“…The conformation of the 2-ethoxy-2-oxoethoxy side chain, including a gauche C e —O—C—C 3 [72.46 (16)°] (e = ethoxy) unit, in the title compound, C 18 H 19 NO 7…”
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Crystal structure, Hirshfeld surface analysis and density functional theory study of benzyl 2-oxo-1-(prop-2-yn-1-yl)-1,2-di-hydro-quinoline-4-carboxyl-ate by Bouzian, Younos, Chkirate, Karim, Mague, Joel T, Al-Ostoot, Fares Hezam, Hammou Ahabchane, Noureddine, Essassi, El Mokhtar

“…The title mol-ecule, C H NO , adopts a -shaped conformation with the carboxyl group nearly coplanar with the di-hydro-quinoline unit. In the crystal,…”
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Crystal structure, Hirshfeld surface analysis, DFT and molecular docking investigation of 2-(2-oxo-1,3-oxazolidin-3-yl)ethyl 2-[2-(2-oxo-1,3-oxazolidin-3-yl)ethoxy]quinoline-4-carboxylate by Bouzian, Younos, Baydere, Cemile, Dege, Necmi, Ahabchane, Noureddine Hamou, Mague, Joel T., Abudunia, Abdulmalik, Karrouchi, Khalid, Essassi, El Mokhtar

“…In the molecular structure of the title compound, C 20 H 21 N 3 O 7 , the quinoline ring system is slightly bent, with a dihedral angle between the phenyl and…”
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Crystal structure, DFT study and Hirshfeld surface analysis of ethyl 6-chloro-2-eth-oxy-quinoline-4-carboxyl-ate by Bouzian, Younos, Karrouchi, Khalid, Anouar, El Hassane, Bouhfid, Rachid, Arshad, Suhana, Essassi, El Mokhtar

“…In the title quinoline derivative, C H ClNO , there is an intra-molecular C-H⋯O hydrogen bond forming an (6) graph-set motif. The mol-ecule is essentially…”
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Crystal structure, Hirshfeld surface analysis, DFT and mol-ecular docking investigation of 2-(2-oxo-1,3-oxazolidin-3-yl)ethyl 2-[2-(2-oxo-1,3-oxazolidin-3-yl)eth-oxy]quinoline-4-carboxyl-ate by Bouzian, Younos, Baydere, Cemile, Dege, Necmi, Ahabchane, Noureddine Hamou, Mague, Joel T, Abudunia, Abdulmalik, Karrouchi, Khalid, Essassi, El Mokhtar

“…In the mol-ecular structure of the title compound, C H N O , the quinoline ring system is slightly bent, with a dihedral angle between the phenyl and the…”
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Crystal structure and Hirshfeld surface analysis of hexyl 1-hexyl-2-oxo-1,2-di-hydro-quinoline-4-carboxyl-ate by Bouzian, Younos, Kansiz, Sevgi, Mahi, Lhassane, Ahabchane, Noureddine Hamou, Mague, Joel T, Dege, Necmi, Karrouchi, Khalid, Essassi, El Mokhtar

“…The asymmetric unit of the title compound, C H NO , comprises of one mol-ecule. The mol-ecule is not planar, with the carboxyl-ate ester group inclined by…”
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Crystal structure and DFT study of benzyl 1-benzyl-2-oxo-1,2-di-hydro-quinoline-4-carboxyl-ate by Bouzian, Younos, Faizi, Md Serajul Haque, Mague, Joel T, Otmani, Bouchaib El, Dege, Necmi, Karrouchi, Khalid, Essassi, El Mokhtar

“…In the title quinoline derivative, C H NO , the two benzyl rings are inclined to the quinoline ring mean plane by 74.09 (8) and 89.43 (7)°, and to each other…”
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1-Ethyl-4-phenyl-1 H -1,5-benzodiazepin-2(3 H )-one by Essaghouani, Abdelhanine, Bouzian, Younos, Essassi, El Mokhtar, Saadi, Mohamed, El Ammari, Lahcen

“…The title compound, C 17 H 16 N 2 O, consists of a benzodiazepin-2-one moiety substituted with a phenyl ring and an ethyl group. The seven-membered diazepine…”
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1-Ethyl-4-phenyl-1H-1,5-benzodiazepin-2(3H)-one by Abdelhanine Essaghouani, Younos Bouzian, El Mokhtar Essassi, Mohamed Saadi, Lahcen El Ammari

“…The title compound, C17H16N2O, consists of a benzodiazepin-2-one moiety substituted with a phenyl ring and an ethyl group. The seven-membered diazepine ring…”
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