Search Results - "Bouzekri, N"

Susceptibility to human type 1 diabetes at IDDM2 is determined by tandem repeat variation at the insulin gene minisatellite locus by Bouzekri, N, Pritchard, L.E, Undlien, D.E, Pociot, F, Merriman, M.E, Bennett, S.T, Kawaguchi, Y, Bain, S.C, Cambon-Thomsen, A, Barnett, A.H, Powell, E.E, Todd, J.A, Nerup, J, Gough, S.C.L, Dronsfield, M.J, Rønningen, K.S, Lucassen, A.M

“…The IDDM2 locus encoding susceptibility to type 1 diabetes was mapped previously to a 4.1-kb region spanning the insulin gene and a minisatellite or variable…”
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SNP Haplotypes in the Angiotensin I‐Converting Enzyme (ACE) Gene: Analysis of Nigerian Family Data Using Gamete Competition Models by McKenzie, C. A., Sinsheimer, J. S., Adeyemo, A. A., Cox, R. D., Southam, L., Hugill, A., Bouzekri, N., Lathrop, M., Forrester, T. E., Cooper, R. S., Ward, R.

“…Summary Gamete competition models were used to explore the relationships between 13 ACE gene polymorphisms and plasma ACE concentration in a set of Nigerian…”
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SNP Haplotypes in the Angiotensin I-Converting Enzyme (ACE) Gene: Analysis of Nigerian Family Data Using Gamete Competition Models by McKenzie, C. A., Sinsheimer, J. S., Adeyemo, A. A., Cox, R. D., Southam, L., Hugill, A., Bouzekri, N., Lathrop, M., Forrester, T. E., Cooper, R. S., Ward, R.

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Strong association between microsatellites and an HLA-B, DR haplotype (B18-DR3): implication for microsatellite evolution by Crouau-Roy, B, Bouzekri, N, Carcassi, C, Clayton, J, Contu, L, Cambon-Thomsen, A

“…The HLA haplotype B18-DR3 has a widespread geographical distribution, but has its greatest frequencies in Southern Europe, probably vestigial of the earliest…”
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Linkage and Association Analysis of Angiotensin I–Converting Enzyme (ACE)–Gene Polymorphisms with ACE Concentration and Blood Pressure by Zhu, Xiaofeng, Bouzekri, Nourdine, Southam, Lorraine, Cooper, Richard S., Adeyemo, Adebowale, McKenzie, Colin A., Luke, Amy, Chen, Guangjie, Elston, Robert C., Ward, Ryk

“…Considerable effort has been expended to determine whether the gene for angiotensin I–converting enzyme (ACE) confers susceptibility to cardiovascular disease…”
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UGT1A1 variation and gallstone formation in sickle cell disease by Haverfield, Eden V., McKenzie, Colin A., Forrester, Terrence, Bouzekri, Nourdine, Harding, Rosalind, Serjeant, Graham, Walker, Thomas, Peto, Tim E.A., Ward, Ryk, Weatherall, David J.

“…Pigment gallstones are a common clinical complication of sickle cell (SS) disease. Genetic variation in the promoter of uridine diphosphate…”
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Genetic evidence in support of a shared Eurasian-North African dairying origin by MYLES, Sean, BOUZEKRI, Nourdine, HAVERFIELD, Eden, CHERKAOUI, Mohamed, DUGOUJON, Jean-Michel, WARD, Ryk

“…The process by which pastoralism and agriculture spread from the Fertile Crescent over the past 10,000 years has been the subject of intense investigation by…”
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Genome Scan Among Nigerians Linking Blood Pressure to Chromosomes 2, 3, and 19 by Cooper, Richard S, Luke, Amy, Zhu, Xiaofeng, Kan, Donghui, Adeyemo, Adebowale, Rorimi, Charles, Bouzekri, Nourdine, Ward, Ryk

“…ABSTRACT—An understanding of the genetic influences on hypertension would help unravel the pathophysiology of this complex disorder and improve our…”
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Angiotensin-1-converting enzyme (ACE) plasma concentration is influenced by multiple ACE-linked quantitative trait nucleotides by Cox, Roger, Bouzekri, Nourdine, Martin, Sabrina, Southam, Lorraine, Hugill, Alison, Golamaully, Mahamadee, Cooper, Richard, Adeyemo, Adebowale, Soubrier, Florent, Ward, Ryk, Lathrop, G. Mark, Matsuda, Fumihiko, Farrall, Martin

“…Circulating angiotensin-1-converting enzyme (ACE) is a highly heritable trait, and a major component of the genetic variance maps to the region of the ACE…”
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A Genome-Wide Scan for Body Mass Index among Nigerian Families by Adeyemo, Adebowale, Luke, Amy, Cooper, Richard, Wu, Xiaodong, Tayo, Bamidele, Zhu, Xiaofeng, Rotimi, Charles, Bouzekri, Nourdine, Ward, Ryk

“…Objective: Interest in mapping genetic variants that are associated with obesity remains high because of the increasing prevalence of obesity and its…”
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Insulin VNTR allele-specific effect in type 1 diabetes depends on identity of untransmitted paternal allele by Undlien, Dag E, Pociot, Flemming, Pugliese, Alberto, Shield, Julian P.H, Polychronakos, Constantin, Bosi, Emanuele, Cucca, Francesco, Bain, Stephen C, Buzzetti, Raffaella, Cambon-Thomsen, Anne, Todd, John A, Bouzekri, Nourdine, Nerup, Jørn, McKinney, Patricia A, Wilson, Amanda J, Esposito, Laura, Nisticò, Lorenza, Bennett, Simon T

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Angiotensin I-converting enzyme polymorphisms, ACE level and blood pressure among Nigerians, Jamaicans and African-Americans by BOUZEKRI, Nourdine, XIAOFENG ZHU, COOPER, Richard S, WARD, Ryk, YANMING JIANG, MCKENZIE, Colin A, LUKE, Amy, FORRESTER, Terrence, ADEYEMO, Adebowale, DONGHUI KAN, FARRALL, Martin, ANDERSON, Simon

“…The genes in the renin-angiotensin system are important physiologic candidates in studies of the genetic susceptibility to hypertension. Limited information…”
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Association between evolutionary history of angiotensinogen haplotypes and plasma levels by FEJERMAN, Laura, BOUZEKRI, Nourdine, XIAODONG WU, ADEYEMO, Adebowale, LUKE, Amy, XIAOFENG ZHU, WARD, Ryk, COOPER, Richard S

“…Over the last decade, considerable effort has been invested in studying the associations between angiotensinogen (AGT) variants, AGT plasma levels and high…”
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Hypervariable Digital DNA Codes for Human Paternal Lineages: MVR-PCR at the Y-specific Minisatellite, MSY1 (DYF155S1) by Jobling, Mark A., Bouzekri, Nourdine, Taylor, Paul G.

“…We describe the first haploid minisatellite, the human Y chromosome-specific locus, MSY1. It consists of an array of 48–114 AT-rich 25 bp repeats of at least…”
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Novel Mutation Processes in the Evolution of a Haploid Minisatellite, MSY1: Array Homogenization Without Homogenization by Bouzekri, Nourdine, Taylor, Paul G., Hammer, Michael F., Jobling, Mark A

“…The Y-specific locus MSY1 is the only known haploid minisatellite, and displays an extremely high degree of structural diversity which can be assayed by…”
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Insulin VNTR allele-specific effect in type 1 diabetes depends on identity of untransmitted paternal allele. The IMDIAB Group by Bennett, S T, Wilson, A J, Esposito, L, Bouzekri, N, Undlien, D E, Cucca, F, Nisticò, L, Buzzetti, R, Bosi, E, Pociot, F, Nerup, J, Cambon-Thomsen, A, Pugliese, A, Shield, J P, McKinney, P A, Bain, S C, Polychronakos, C, Todd, J A

“…The IDDM2 type 1 diabetes susceptibility locus was mapped to and identified as allelic variation at the insulin gene (INS) VNTR regulatory polymorphism. In…”
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Insulin expression: is VNTR allele 698 really anomalous? by McGinnis, Ralph E, Spielman, Richard S

“…Two recent papers in Nature Genetics report that insulin mRNA expression is correlated with the length of the polymorphic VNTR immediately 5' to the insulin…”
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