Search Results - "Bouwmeester, T."

Activation of Yap-Directed Transcription by Knockdown of Conserved Cellular Functions by Agarinis, C, Orsini, V, Megel, P, Abraham, Y, Yang, H, Mickanin, C, Myer, V, Bouwmeester, T, Tchorz, J S, Parker, C N

“…The Yap-Hippo pathway has a significant role in regulating cell proliferation and growth, thus controlling organ size and regeneration. The Hippo pathway…”
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The Spemann-Mangold organizer: the control of fate specification and morphogenetic rearrangements during gastrulation in Xenopus by Bouwmeester, T

“…Vertebrate embryonic development is controlled by sequentially operating signalling centres that organize spatial pattern by inductive interactions. The…”
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Essential role of Bmp7 (snailhouse) and its prodomain in dorsoventral patterning of the zebrafish embryo by Dick, A, Hild, M, Bauer, H, Imai, Y, Maifeld, H, Schier, A F, Talbot, W S, Bouwmeester, T, Hammerschmidt, M

“…Bone morphogenetic proteins (Bmps) are signaling molecules that have been implicated in a variety of inductive processes. We report here that zebrafish Bmp7 is…”
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The role of paraxial protocadherin in selective adhesion and cell movements of the mesoderm during Xenopus gastrulation by Kim, S H, Yamamoto, A, Bouwmeester, T, Agius, E, Robertis, E M

“…Paraxial Protocadherin (PAPC) encodes a transmembrane protein expressed initially in Spemann's organizer and then in paraxial mesoderm. Together with another…”
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The smad5 mutation somitabun blocks Bmp2b signaling during early dorsoventral patterning of the zebrafish embryo by Hild, M, Dick, A, Rauch, G J, Meier, A, Bouwmeester, T, Haffter, P, Hammerschmidt, M

“…Signaling by members of the TGFbeta superfamily is thought to be transduced by Smad proteins. Here, we describe a zebrafish mutant in smad5, designated…”
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Identification of human mutations in TRAF3IP1 in patients with nephronophthisis and retinal degeneration by Becker-Heck, A, Bizet, A, Ryan, R, Krug, P, Filhol, E, Linghu, B, Oakeley, E, Serluca, F, Legendre, F, Dörner, N, Lasbennes, MC, Duca, J, Yang, F, Damask, A, Klickstein, L, Labow, M, Schebesta, M, Bouwmeester, T, Valette, H, Pinson, L, Goubaux, B, Dubot, P, Salomon, R, Antignac, C, Gubler, M, Jeanpierre, C, Chibout, S, Bole-Feysot, C, Nitschké, P, Benmerah, A, Szustakowski, JD, Sailer, AW, Saunier, S, Saint-Mezard, P

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Xwig1, a novel putative endoplasmic reticulum protein expressed during epithelial morphogenesis and in response to embryonic wounding by Klingbeil, P, Frazzetto, G, Bouwmeester, T

“…In a subtractive differential screening, we identified a novel gene with interesting characteristics, termed Xenopus wounding induced gene 1 (Xwig1). Xwig1…”
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Structural Basis of BRCC36 Function in DNA Repair and Immune Regulation by Rabl, Julius, Bunker, Richard D., Schenk, Andreas D., Cavadini, Simone, Gill, Mark E., Abdulrahman, Wassim, Andrés-Pons, Amparo, Luijsterburg, Martijn S., Ibrahim, Adel F.M., Branigan, Emma, Aguirre, Jacob D., Marceau, Aimee H., Guérillon, Claire, Bouwmeester, Tewis, Hassiepen, Ulrich, Peters, Antoine H.F.M., Renatus, Martin, Gelman, Laurent, Rubin, Seth M., Mailand, Niels, van Attikum, Haico, Hay, Ronald T., Thomä, Nicolas H.

“…In mammals, ∼100 deubiquitinases act on ∼20,000 intracellular ubiquitination sites. Deubiquitinases are commonly regarded as constitutively active, with…”
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Evolutionary Conserved Modules Associated with Zinc Fingers in Xenopus laevis by Knöchel, W., Pöting, A., Köster, M., El Baradi, T., Nietfeld, W., Bouwmeester, T., Pieler, T.

“…Many DNA-binding proteins that are involved in the differential regulation of gene expression are composed of multiple discrete modules. Association of the…”
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Human protein–protein interaction networks and the value for drug discovery by Ruffner, Heinz, Bauer, Andreas, Bouwmeester, Tewis

“…Systematic genome-wide and pathway-specific protein–protein interaction screens have generated a putative, organizing framework of the spatial…”
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FRI-119 - Liver biopsy derived induced pluripotent stem cells provide unlimited supply for the generation of hepatocyte-like cells by Calabrese, D., Roma, G., Bergling, S., Carbone, W., Mele, V., Nuciforo, S., Fofana, I., Campana, B., Szkolnicka, D., Hay, D., Tchorz, J., Bouwmeester, T., Wieland, S., Heim, M.

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Liver biopsy derived induced pluripotent stem cells provide unlimited supply for the generation of hepatocyte-like cells by Calabrese, D., Roma, G., Bergling, S., Carbone, W., Mele, V., Nuciforo, S., Fofana, I., Campana, B., Szkolnicka, D., Hay, D., Tchorz, J., Bouwmeester, T., Wieland, S., Heim, M.

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Isolation, characterization, and evolutionary aspects of a cDNA clone encoding multiple neuropeptides involved in the stereotyped egg-laying behavior of the freshwater snail Lymnaea stagnalis by Vreugdenhil, E, Jackson, JF, Bouwmeester, T, Smit, AB, Van Minnen, J, Van Heerikhuizen, H, Klootwijk, J, Joosse, J

“…The cerebral neurosecretory caudodorsal cells (CDCs) of the freshwater pulmonate snail Lymnaea stagnalis control egg laying, an event that involves a pattern…”
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A physical and functional map of the human TNF-α/NF-κB signal transduction pathway by Bouwmeester, Tewis, Superti-Furga, Giulio, Bauch, Angela, Ruffner, Heinz, Angrand, Pierre-Olivier, Bergamini, Giovanna, Croughton, Karen, Cruciat, Cristina, Eberhard, Dirk, Gagneur, Julien, Ghidelli, Sonja, Hopf, Carsten, Huhse, Bettina, Mangano, Raffaella, Michon, Anne-Marie, Schirle, Markus, Schlegl, Judith, Schwab, Markus, Stein, Martin A, Bauer, Andreas, Casari, Georg, Drewes, Gerard, Gavin, Anne-Claude, Jackson, David B, Joberty, Gerard, Neubauer, Gitte, Rick, Jens, Kuster, Bernhard

“…Signal transduction pathways are modular composites of functionally interdependent sets of proteins that act in a coordinated fashion to transform…”
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Modular decomposition of protein-protein interaction networks by Gagneur, Julien, Krause, Roland, Bouwmeester, Tewis, Casari, Georg

“…We introduce an algorithmic method, termed modular decomposition, that defines the organization of protein-interaction networks as a hierarchy of nested…”
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Comprehensive Proteomic Analysis of Human Par Protein Complexes Reveals an Interconnected Protein Network by Brajenovic, Miro, Joberty, Gerard, Küster, Bernhard, Bouwmeester, Tewis, Drewes, Gerard

“…The polarization of eukaryotic cells is controlled by the concerted activities of asymmetrically localized proteins. The PAR proteins, first identified in…”
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Patterning by genes expressed in Spemann's organizer by De Robertis, E M, Kim, S, Leyns, L, Piccolo, S, Bachiller, D, Agius, E, Belo, J A, Yamamoto, A, Hainski-Brousseau, A, Brizuela, B, Wessely, O, Lu, B, Bouwmeester, T

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The head inducer Cerberus is a multifunctional antagonist of Nodal, BMP and Wnt signals by Robertis, E. M. De, Piccolo, Stefano, Agius, Eric, Leyns, Luc, Bhattacharyya, Subha, Grunz, Horst, Bouwmeester, Tewis

“…Embryological and genetic evidence indicates that the vertebrate head is induced by a different set of signals from those that organize trunk-tail development…”
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Global approaches to protein–protein interactions by Drewes, Gerard, Bouwmeester, Tewis

“…The availability of complete, annotated genome sequences for a variety of eukaryotic organisms has paved the way for a paradigm shift in biomedical research…”
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Proteome survey reveals modularity of the yeast cell machinery by Gavin, A.C, Aloy, P, Grandi, P, Krause, R, Boesche, M, Marzioch, M, Rau, C, Jensen, L.J, Bastuck, S, Dümpelfeld, B

“…Protein complexes are key molecular entities that integrate multiple gene products to perform cellular functions. Here we report the first genome-wide screen…”
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