Search Results - "Bouwer, James C"
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Molecular basis for RNA polymerase-dependent transcription complex recycling by the helicase-like motor protein HelD
Published in Nature communications (18-12-2020)“…In bacteria, transcription complexes stalled on DNA represent a major source of roadblocks for the DNA replication machinery that must be removed in order to…”
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2
Redβ177 annealase structure reveals details of oligomerization and λ Red-mediated homologous DNA recombination
Published in Nature communications (26-09-2022)“…The Redβ protein of the bacteriophage λ red recombination system is a model annealase which catalyzes single-strand annealing homologous DNA recombination…”
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3
Variation in structural motifs within SARS-related coronavirus spike proteins
Published in PLoS pathogens (28-05-2024)“…SARS-CoV-2 is the third known coronavirus (CoV) that has crossed the animal-human barrier in the last two decades. However, little structural information…”
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4
Structural characterisation of the complete cycle of sliding clamp loading in Escherichia coli
Published in Nature communications (27-09-2024)“…Ring-shaped DNA sliding clamps are essential for DNA replication and genome maintenance. Clamps need to be opened and chaperoned onto DNA by clamp loader…”
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5
Cryo-EM reveals distinct conformations of E. coli ATP synthase on exposure to ATP
Published in eLife (26-03-2019)“…ATP synthase produces the majority of cellular energy in most cells. We have previously reported cryo-EM maps of autoinhibited ATP synthase imaged without…”
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6
Potassium dependent structural changes in the selectivity filter of HERG potassium channels
Published in Nature communications (29-08-2024)“…The fine tuning of biological electrical signaling is mediated by variations in the rates of opening and closing of gates that control ion flux through…”
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7
Mechanism of transcription modulation by the transcription-repair coupling factor
Published in Nucleic acids research (10-06-2022)“…Abstract Elongation by RNA polymerase is dynamically modulated by accessory factors. The transcription-repair coupling factor (TRCF) recognizes paused/stalled…”
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Non‐Flammable Ester Electrolyte with Boosted Stability Against Li for High‐Performance Li Metal Batteries
Published in Angewandte Chemie (International ed.) (10-10-2022)“…In traditional non‐flammable electrolytes a trade‐off always exists between non‐flammability and battery performance. Previous research focused on reducing…”
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9
Transform-based backprojection for volume reconstruction of large format electron microscope tilt series
Published in Journal of structural biology (01-05-2006)“…Alignment of the individual images of a tilt series is a critical step in obtaining high-quality electron microscope reconstructions. We report on general…”
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10
Epitaxial Nickel Ferrocyanide Stabilizes Jahn–Teller Distortions of Manganese Ferrocyanide for Sodium‐Ion Batteries
Published in Angewandte Chemie International Edition (16-08-2021)“…Manganese‐based Prussian Blue, Na2−δMn[Fe(CN)6] (MnPB), is a good candidate for sodium‐ion battery cathode materials due to its high capacity. However, it…”
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11
Characterization of a direct detection device imaging camera for transmission electron microscopy
Published in Ultramicroscopy (01-06-2010)“…The complete characterization of a novel direct detection device (DDD) camera for transmission electron microscopy is reported, for the first time at primary…”
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12
Deceleration of probe beam by stage bias potential improves resolution of serial block-face scanning electron microscopic images
Published in Advanced structural and chemical imaging (15-09-2016)“…Serial block-face scanning electron microscopy (SBEM) is quickly becoming an important imaging tool to explore three-dimensional biological structure across…”
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13
Non‐Flammable Ester Electrolyte with Boosted Stability Against Li for High‐Performance Li Metal Batteries
Published in Angewandte Chemie (10-10-2022)“…In traditional non‐flammable electrolytes a trade‐off always exists between non‐flammability and battery performance. Previous research focused on reducing…”
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Journal Article -
14
Epitaxial Nickel Ferrocyanide Stabilizes Jahn–Teller Distortions of Manganese Ferrocyanide for Sodium‐Ion Batteries
Published in Angewandte Chemie (16-08-2021)“…Manganese‐based Prussian Blue, Na2−δMn[Fe(CN)6] (MnPB), is a good candidate for sodium‐ion battery cathode materials due to its high capacity. However, it…”
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Journal Article -
15
Applications of direct detection device in transmission electron microscopy
Published in Journal of structural biology (01-03-2008)“…A prototype direct detection device (DDD) camera system has shown great promise in improving both the spatial resolution and the signal to noise ratio for…”
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16
Improving signal to noise in labeled biological specimens using energy-filtered TEM of sections with a drift correction strategy and a direct detection device
Published in Microscopy and microanalysis (01-06-2014)“…Energy filtered transmission electron microscopy techniques are regularly used to build elemental maps of spatially distributed nanoparticles in materials and…”
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17
Active pixel sensor array as a detector for electron microscopy
Published in Ultramicroscopy (01-09-2005)“…A new high-resolution recording device for transmission electron microscopy (TEM) is urgently needed. Neither film nor CCD cameras are systems that allow for…”
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18
Automated most-probable loss tomography of thick selectively stained biological specimens with quantitative measurement of resolution improvement
Published in Journal of structural biology (01-12-2004)“…We describe the technique and application of energy filtering, automated most-probable loss (MPL) tomography to intermediate voltage electron microscopy…”
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19
Future Directions for Camera Systems in Electron Microscopy
Published in Methods in Cell Biology (2007)“…Charge-coupled device (CCD) invented in 1970, soon became the sensor of choice in many imaging applications, particularly for video cameras and camcorders…”
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The Application of Energy‐Filtered Electron Microscopy to Tomography of Thick, Selectively Stained Biological Samples
Published in Methods in Cell Biology (2007)“…This chapter describes the use of energy-filtered electron microscopy (EM) to enhance contrast and reduce the chromatic aberration in the imaging of thick,…”
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Book Chapter Journal Article