Search Results - "Bouvier, Jacques"
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Evolution: Unearthing missing links in the origin of our planet's primary carbon-fixing enzyme
Published in Current biology (18-12-2023)“…Form I rubisco underpins life on Earth, but the origins of its anomalous and highly complex multimeric structure have long proven elusive. New research helps…”
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Response to Tcherkez and Farquhar: Rubisco adaptation is more limited by phylogenetic constraint than by catalytic trade-off
Published in Journal of plant physiology (01-08-2023)“…Rubisco is the primary entry point for carbon into the biosphere. It has been widely proposed that rubisco is highly constrained by catalytic trade-offs due to…”
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Rubisco is evolving for improved catalytic efficiency and CO2 assimilation in plants
Published in Proceedings of the National Academy of Sciences - PNAS (12-03-2024)“…Rubisco is the primary entry point for carbon into the biosphere. However, rubisco is widely regarded as inefficient leading many to question whether the…”
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Rubisco is evolving for improved catalytic efficiency and CO 2 assimilation in plants
Published in Proceedings of the National Academy of Sciences - PNAS (12-03-2024)“…Rubisco is the primary entry point for carbon into the biosphere. However, rubisco is widely regarded as inefficient leading many to question whether the…”
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Rubisco Adaptation Is More Limited by Phylogenetic Constraint Than by Catalytic Trade-off
Published in Molecular biology and evolution (01-07-2021)“…Abstract Rubisco assimilates CO2 to form the sugars that fuel life on earth. Correlations between rubisco kinetic traits across species have led to the…”
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Brassicaceae display variation in efficiency of photorespiratory carbon-recapturing mechanisms
Published in Journal of experimental botany (21-11-2023)“…Carbon-concentrating mechanisms enhance the carboxylase efficiency of Rubisco by providing supra-atmospheric concentrations of CO2 in its surroundings. Beside…”
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C 4 anatomy can evolve via a single developmental change
Published in Ecology letters (01-02-2019)“…C photosynthesis is a complex trait that boosts productivity in warm environments. Paradoxically, it evolved independently in numerous plant lineages, despite…”
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C4 anatomy can evolve via a single developmental change
Published in Ecology letters (01-02-2019)“…C4 photosynthesis is a complex trait that boosts productivity in warm environments. Paradoxically, it evolved independently in numerous plant lineages, despite…”
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A new class of anthelmintics effective against drug-resistant nematodes
Published in Nature (13-03-2008)“…Anthelmintic resistance in human and animal pathogenic helminths has been spreading in prevalence and severity to a point where multidrug resistance against…”
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Development of a movement-based in vitro screening assay for the identification of new anti-cestodal compounds
Published in PLoS neglected tropical diseases (17-05-2017)“…Intestinal cestodes are infecting millions of people and livestock worldwide, but treatment is mainly based on one drug: praziquantel. The identification of…”
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acr-23 Encodes a monepantel-sensitive channel in Caenorhabditis elegans
Published in PLoS pathogens (01-08-2013)“…Monepantel is a member of the recently identified class of anthelmintics known as the amino-acetonitrile derivatives (AADs). Monepantel controls all major…”
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High level efficacy of lufenuron against sea lice (Lepeophtheirus salmonis) linked to rapid impact on moulting processes
Published in International journal for parasitology -- drugs and drug resistance (01-08-2018)“…Drug resistance in the salmon louse Lepeophtheirus salmonis is a global issue for Atlantic salmon aquaculture. Multiple resistance has been described across…”
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The proteases and pathogenicity of parasitic protozoa
Published in Annual review of microbiology (1993)“…Protozoan parasites are among the most prevalent pathogens worldwide. Diseases like malaria, leishmaniasis, amebiasis, and trypanosomiasis affect hundreds of…”
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A unique signature identifies a family of zinc-dependent metallopeptidases
Published in FEBS letters (02-01-1989)“…The primary sequence motif HExxH has been found in many zinc-dependent endopeptidases. We show that a larger signature comprising this sequence is common to…”
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Evolution of a plant growth-regulatory protein interaction specificity
Published in Nature plants (01-12-2023)“…Specific protein–protein interactions (PPIs) enable biological regulation. However, the evolution of PPI specificity is little understood. Here we trace the…”
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Worms—A “license to kill”
Published in Veterinary parasitology (01-08-2013)“…Worm infections can cause severe harm and death to both humans and numerous domestic and wild animals. Despite the fact that there are many beneficial worm…”
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WormsaA alicense to killa
Published in Veterinary parasitology (01-08-2013)“…Worm infections can cause severe harm and death to both humans and numerous domestic and wild animals. Despite the fact that there are many beneficial worm…”
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acr-23 Encodes a Monepantel-Sensitive Channel in Caenorhabditis elegans: e1003524
Published in PLoS pathogens (01-08-2013)“…Monepantel is a member of the recently identified class of anthelmintics known as the amino-acetonitrile derivatives (AADs). Monepantel controls all major…”
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Discovery of amino-acetonitrile derivatives, a new class of synthetic anthelmintic compounds
Published in Bioorganic & medicinal chemistry (01-05-2008)“…The discovery and SAR of a new series of amino-acetonitrile derivatives (AAD) potent against parasitic nematode species are reported. A new series of…”
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Novel peptide inhibitors of Leishmania gp63 based on the cleavage site of MARCKS (myristoylated alanine-rich C kinase substrate)-related protein
Published in Biochemical journal (01-11-2002)“…The zinc metalloprotease gp63 (leishmanolysin; promastigote surface protease) is expressed at high density at the surface of Leishmania promastigotes…”
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