Search Results - "Boutwell, R K"

Protein kinase activity associated with a phorbol ester receptor purified from mouse brain by ASHENDEL, C. L, STALLER, J. M, BOUTWELL, R. K

“…Protein kinase activity copurified with the receptor for 12-O-[3H]tetradecanoylphorbol-13-acetate during its purification from mouse brain particulate protein…”
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Correlation of the inhibition by retinoids of tumor promoter-induced mouse epidermal ornithine decarboxylase activity and of skin tumor promotion by Verma, A K, Shapas, B G, Rice, H M, Boutwell, R K

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Induction of the polyamine-biosynthetic enzymes in mouse epidermis by tumor-promoting agents by O'Brien, T G, Simsiman, R C, Boutwell, R K

“…A single topical application of 1.0 mg of crotol oil or 17 nmoles of 12-O-tetradecanoyl-phorbol-13-acetate (TPA) resulted in a rapid, transient stimulation of…”
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Inhibition of mouse skin tumor promotion and of promoter-stimulated epidermal polyamine biosynthesis by α-difluoromethylornithine by TAKIGAWA, M, VERMA, A. K, SIMSIMAN, R. C, BOUTWELL, R. K

“…Application of the tumor-promoting agent 12-O-tetradecanoylphorbol-13-acetate (TPA) to mouse skin leads to a manifold induction of ornithine decarboxylase…”
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Historical perspective: calories and energy expenditure in carcinogenesis by Pariza, M W, Boutwell, R K

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Nutrition and carcinogenesis: historical highlights and future prospects by Boutwell, R K

“…Historical reviews were presented of several selected nutritional factors that are determinants of cancer incidence in laboratory experiments utilizing…”
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Differential effects of retinoic acid and 7,8-benzoflavone on the induction of mouse skin tumors by the complete carcinogenesis process and by the initiation-promotion regimen by Verma, A K, Conrad, E A, Boutwell, R K

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Induction of the polyamine-biosynthetic enzymes in mouse epidermis and their specificity for tumor promotion by O'Brien, T G, Simsiman, R C, Boutwell, R K

“…The induction of ornithine decarboxylase and S-adenosyl-L-methionine decarboxylase in mouse epidermis by various classes of tumor-promoting and nonpromoting…”
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Inhibition by prostaglandin synthesis inhibitors of the induction of epidermal ornithine decarboxylase activity, the accumulation of prostaglandins, and tumor promotion caused by 12-O-tetradecanoylphorbol-13-acetate by Verma, A K, Ashendel, C L, Boutwell, R K

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Inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced ornithine decarboxylase activity in mouse epidermis by vitamin A analogs (retinoids) by Verma, A K, Rice, H M, Shapas, B G, Boutwell, R K

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Enhancement by 3-isobutyl-1-methylxanthine and cholera toxin of 12-O-tetradecanoylphorbol-13-acetate-stimulated cyclic nucleotide levels and ornithine decarboxylase activity in isolated epidermal cells by Perchellet, J P, Boutwell, R K

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Induction of mouse epidermal ornithine decarboxylase activity and DNA synthesis by ultraviolet light by Verma, A K, Lowe, N J, Boutwell, R K

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Vitamin A acid (retinoic acid), a potent inhibitor of 12-O-tetradecanoyl-phorbol-13-acetate-induced ornithine decarboxylase activity in mouse epidermis by Verma, A K, Boutwell, R K

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Effects of 12-O-tetradecanoylphorbol-13-acetate and mezerein on epidermal ornithine decarboxylase activity, isoproterenol-stimulated levels of cyclic adenosine 3':5'-monophosphate, and induction of mouse skin tumors in vivo by Mufson, R A, Fischer, S M, Verma, A K, Gleason, G L, Slaga, T J, Boutwell, R K

“…The tumor promoter 12-O-tetradecanoylphorbol-13-acetate and the antileukemic agent mezerein are diterpene esters of plant origin with certain structural…”
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The biochemistry of preneoplasia in mouse skin by Boutwell, R K

“…After an introduction to the "Session on Skin" emphasizing that some early biochemical changes occurring in the two-stage model system for skin would be…”
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Studies on the mechanism of skin tumor promotion by Hennings, H, Boutwell, R K

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Effects of dose and duration of treatment with the tumor-promoting agent, 12-O-tetradecanoylphorbol-13-acetate on mouse skin carcinogenesis by Verma, A K, Boutwell, R K

“…The effects of dose and duration of treatment with the potent tumor-promoting agent 12-O-tetradecanoylphorbol-13-acetate (TPA) on the formation of skin tumors…”
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Tumor promoter-induced refractory state against ornithine decarboxylase induction by 12-O-tetradecanoylphorbol-13-acetate in mouse epidermis by TAKIGAWA, M, SIMSIMAN, R. C, BOUTWELL, R. K

“…More than one application of the potent tumor-promoting agent, 12-O-tetradecanoylphorbol-13-acetate (TPA), to mouse skin at intervals of more than 48 h led to…”
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Solubilization, purification, and reconstitution of a phorbol ester receptor from the particulate protein fraction of mouse brain by ASHENDEL, C. L, STALLER, J. M, BOUTWELL, R. K

“…The protein that specifically binds 12-O-[3H]tetradecanoyl-phorbol-13-acetate was solubilized from mouse brain particulate protein with detergents and purified…”
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Inhibition of 7-bromomethylbenz[a]anthracene-promoted mouse skin tumor formation by retinoic acid and dexamethasone by Verma, A K, Garcia, C T, Ashendel, C L, Boutwell, R K

“…Retinoic acid, a potent inhibitor of mouse skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate, fails to inhibit tumor formation by the complete…”
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