Search Results - "Bouton, Cecile"

Redox Control of the Human Iron-Sulfur Repair Protein MitoNEET Activity via Its Iron-Sulfur Cluster by Golinelli-Cohen, Marie-Pierre, Lescop, Ewen, Mons, Cécile, Gonçalves, Sergio, Clémancey, Martin, Santolini, Jérôme, Guittet, Eric, Blondin, Geneviève, Latour, Jean-Marc, Bouton, Cécile

“…Human mitoNEET (mNT) is the first identified Fe-S protein of the mammalian outer mitochondrial membrane. Recently, mNT has been implicated in cytosolic Fe-S…”
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The antimalarial drug primaquine targets Fe-S cluster proteins and yeast respiratory growth by Lalève, Anaïs, Vallières, Cindy, Golinelli-Cohen, Marie-Pierre, Bouton, Cécile, Song, Zehua, Pawlik, Grzegorz, Tindall, Sarah M, Avery, Simon V, Clain, Jérôme, Meunier, Brigitte

“…Malaria is a major health burden in tropical and subtropical countries. The antimalarial drug primaquine is extremely useful for killing the transmissible…”
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The first cellular models based on frataxin missense mutations that reproduce spontaneously the defects associated with Friedreich ataxia by Calmels, Nadège, Schmucker, Stéphane, Wattenhofer-Donzé, Marie, Martelli, Alain, Vaucamps, Nadège, Reutenauer, Laurence, Messaddeq, Nadia, Bouton, Cécile, Koenig, Michel, Puccio, Hélène

“…Friedreich ataxia (FRDA), the most common form of recessive ataxia, is due to reduced levels of frataxin, a highly conserved mitochondrial iron-chaperone…”
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The H2O2‑Resistant Fe–S Redox Switch MitoNEET Acts as a pH Sensor To Repair Stress-Damaged Fe–S Protein by Mons, Cécile, Botzanowski, Thomas, Nikolaev, Anton, Hellwig, Petra, Cianférani, Sarah, Lescop, Ewen, Bouton, Cécile, Golinelli-Cohen, Marie-Pierre

“…Human mitoNEET (mNT) is the first identified Fe–S protein of the mammalian outer mitochondrial membrane. Recently, we demonstrated the involvement of mNT in a…”
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Dysfunction in the mitochondrial Fe-S assembly machinery leads to formation of the chemoresistant truncated VDAC1 isoform without HIF-1α activation by Ferecatu, Ioana, Canal, Frédéric, Fabbri, Lucilla, Mazure, Nathalie M, Bouton, Cécile, Golinelli-Cohen, Marie-Pierre

“…Biogenesis of iron-sulfur clusters (ISC) is essential to almost all forms of life and involves complex protein machineries. This process is initiated within…”
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The Diabetes Drug Target MitoNEET Governs a Novel Trafficking Pathway to Rebuild an Fe-S Cluster into Cytosolic Aconitase/Iron Regulatory Protein 1 by Ferecatu, Ioana, Gonçalves, Sergio, Golinelli-Cohen, Marie-Pierre, Clémancey, Martin, Martelli, Alain, Riquier, Sylvie, Guittet, Eric, Latour, Jean-Marc, Puccio, Hélène, Drapier, Jean-Claude, Lescop, Ewen, Bouton, Cécile

“…In eukaryotes, mitochondrial iron-sulfur cluster (ISC), export and cytosolic iron-sulfur cluster assembly (CIA) machineries carry out biogenesis of iron-sulfur…”
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Nitric oxide activates an Nrf2/sulfiredoxin antioxidant pathway in macrophages by Abbas, Kahina, Breton, Jacques, Planson, Anne-Gaelle, Bouton, Cécile, Bignon, Jérome, Seguin, Cendrine, Riquier, Sylvie, Toledano, Michel B., Drapier, Jean-Claude

“…Peroxiredoxins (Prx's) are a family of peroxidases that maintain thiol homeostasis by catalyzing the reduction of organic hydroperoxides, H2O2, and…”
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Mycobacterium avium infection induces H-ferritin expression in mouse primary macrophages by activating Toll-like receptor 2 by Silva-Gomes, Sandro, Bouton, Cécile, Silva, Tânia, Santambrogio, Paolo, Rodrigues, Pedro, Appelberg, Rui, Gomes, Maria Salomé

“…Important for both host and pathogen survivals, iron is a key factor in determining the outcome of an infectious process. Iron with-holding, including…”
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Iron Regulatory Protein 1 Outcompetes Iron Regulatory Protein 2 in Regulating Cellular Iron Homeostasis in Response to Nitric Oxide by Styś, Agnieszka, Galy, Bruno, Starzyński, Rafal R., Smuda, Ewa, Drapier, Jean-Claude, Lipiński, Pawel, Bouton, Cécile

“…In mammals, iron regulatory proteins (IRPs) 1 and 2 posttranscriptionally regulate expression of genes involved in iron metabolism, including transferrin…”
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Combined Biochemical, Biophysical, and Cellular Methods to Study Fe-S Cluster Transfer and Cytosolic Aconitase Repair by MitoNEET by Mons, Cécile, Ferecatu, Ioana, Riquier, Sylvie, Lescop, Ewen, Bouton, Cécile, Golinelli-Cohen, Marie-Pierre

“…MitoNEET is the first identified Fe-S protein anchored to mammalian outer mitochondrial membranes with the vast majority of the protein polypeptide located in…”
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Regulation of Peroxiredoxins by Nitric Oxide in Immunostimulated Macrophages by Diet, Alexandre, Abbas, Kahina, Bouton, Cécile, Guillon, Blanche, Tomasello, Flora, Fourquet, Simon, Toledano, Michel B., Drapier, Jean-Claude

“…Reactive oxygen species and nitric oxide (NO) are capable of both mediating redox-sensitive signal transduction and eliciting cell injury. The interplay…”
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Real-Time Amperometric Analysis of Reactive Oxygen and Nitrogen Species Released by Single Immunostimulated Macrophages by Amatore, Christian, Arbault, Stéphane, Bouton, Cécile, Drapier, Jean-Claude, Ghandour, Hala, Koh, Alaric C.W

“…Macrophages are key cells of the immune system. Immunologically activated macrophages are known to release a cocktail of reactive oxygen and nitrogen species…”
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Signaling events leading to peroxiredoxin 5 up-regulation in immunostimulated macrophages by Abbas, Kahina, Breton, Jacques, Picot, Cédric R., Quesniaux, Valérie, Bouton, Cécile, Drapier, Jean-Claude

“…Peroxiredoxins (PRXs) are thiol peroxidases associated with many cellular functions including proliferation, cell cycle, apoptosis, and differentiation. There…”
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Monitoring in Real Time with a Microelectrode the Release of Reactive Oxygen and Nitrogen Species by a Single Macrophage Stimulated by its Membrane Mechanical Depolarization by Amatore, Christian, Arbault, Stéphane, Bouton, Cécile, Coffi, Karen, Drapier, Jean-Claude, Ghandour, Hala, Tong, Yuehong

“…Macrophages are key cells of the immune system. During phagocytosis, the macrophage engulfs a foreign bacterium, virus, or particle into a vacuole, the…”
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Frataxin deficiency causes upregulation of mitochondrial Lon and ClpP proteases and severe loss of mitochondrial Fe-S proteins by Guillon, Blanche, Bulteau, Anne-Laure, Wattenhofer-Donzé, Marie, Schmucker, Stéphane, Friguet, Bertrand, Puccio, Hélène, Drapier, Jean-Claude, Bouton, Cécile

“…Friedreich ataxia (FRDA) is a rare hereditary neurodegenerative disease characterized by progressive ataxia and cardiomyopathy. The cause of the disease is a…”
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Peroxiredoxin post-translational modifications by redox messengers by Riquier, Sylvie, Breton, Jacques, Abbas, Kahina, Cornu, David, Bouton, Cécile, Drapier, Jean-Claude

“…Peroxiredoxins (Prxs) are a family of thiol peroxidases that participate in hydroperoxide detoxification and regulates H2O2 signaling. In mammals, the four…”
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Friedreich ataxia: the oxidative stress paradox by Seznec, Hervé, Simon, Delphine, Bouton, Cécile, Reutenauer, Laurence, Hertzog, Ariane, Golik, Pawel, Procaccio, Vincent, Patel, Manisha, Drapier, Jean-Claude, Koenig, Michel, Puccio, Hélène

“…Friedreich ataxia (FRDA) results from a generalized deficiency of mitochondrial and cytosolic iron–sulfur protein activity initially ascribed to mitochondrial…”
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Endogenous nitration of iron regulatory protein-1 (IRP-1) in nitric oxide-producing murine macrophages: further insight into the mechanism of nitration in vivo and its impact on IRP-1 functions by Gonzalez, Deyarina, Drapier, Jean-Claude, Bouton, Cécile

“…Iron regulatory protein-1 (IRP-1) is a bifunctional [4Fe-4S] protein that functions as a cytosolic aconitase or as a trans-regulatory factor controlling iron…”
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RNA Silencing of Mitochondrial m-Nfs1 Reduces Fe-S Enzyme Activity Both in Mitochondria and Cytosol of Mammalian Cells by Fosset, Cédric, Chauveau, Marie-Jeanne, Guillon, Blanche, Canal, Frédéric, Drapier, Jean-Claude, Bouton, Cécile

“…In prokaryotes and yeast, the general mechanism of biogenesis of iron-sulfur (Fe-S) clusters involves activities of several proteins among which IscS and Nfs1p…”
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Distinct regulation of iron homeostasis in rat heart and liver in response to systemic iron deficiency by Gressette, Mélanie, Bedouet, Kaveen, Deschemin, Jean-Christophe, Domergue, Valérie, Lefebvre, Florence, Bruneel, Arnaud, Vaulont, Sophie, Mericskay, Mathias, Bouton, Cecile, Garnier, Anne

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