Search Results - "Boutin, Molly E."

A high-throughput imaging and nuclear segmentation analysis protocol for cleared 3D culture models by Boutin, Molly E., Voss, Ty C., Titus, Steven A., Cruz-Gutierrez, Kennie, Michael, Sam, Ferrer, Marc

“…Imaging and subsequent segmentation analysis in three-dimensional (3D) culture models are complicated by the light scattering that occurs when collecting…”
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A three-dimensional neural spheroid model for capillary-like network formation by Boutin, Molly E., Kramer, Liana L., Livi, Liane L., Brown, Tyler, Moore, Christopher, Hoffman-Kim, Diane

“…[Display omitted] •A three-dimensional neural spheroid model to study capillary-like structure formation is proposed.•Endothelial cells within mixed cortical…”
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Application and assessment of optical clearing methods for imaging of tissue-engineered neural stem cell spheres by Boutin, Molly E, Hoffman-Kim, Diane

“…Three-dimensional (3D) cell culture is an important tool that facilitates biological discoveries by bridging the divide between standard two-dimensional cell…”
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High throughput 3D gel-based neural organotypic model for cellular assays using fluorescence biosensors by Kundu, Srikanya, Boutin, Molly E., Strong, Caroline E., Voss, Ty, Ferrer, Marc

“…Three-dimensional (3D) organotypic models that capture native-like physiological features of tissues are being pursued as clinically predictive assays for…”
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A multiparametric calcium signal screening platform using iPSC-derived cortical neural spheroids by Boutin, Molly E, Strong, Caroline E, Van Hese, Brittney, Hu, Xin, Itkin, Zina, Chen, Yu-Chi, LaCroix, Andrew, Gordon, Ryan, Guicherit, Oivin, Carromeu, Cassiano, Kundu, Srikanya, Lee, Emily, Ferrer, Marc

“…Discovery of therapeutics for neurological diseases is hampered by the lack of predictive in vitro and in vivo models. Traditionally, in vitro assays rely on…”
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Enhancement of Neuroglial Extracellular Matrix Formation and Physiological Activity of Dopaminergic Neural Cocultures by Macromolecular Crowding by Vo, Andy N, Kundu, Srikanya, Strong, Caroline, Jung, Olive, Lee, Emily, Song, Min Jae, Boutin, Molly E, Raghunath, Michael, Ferrer, Marc

“…The neuroglial extracellular matrix (ECM) provides critical support and physiological cues for the proper growth, differentiation, and function of neuronal…”
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Three-Dimensional Neural Spheroid Culture: An In Vitro Model for Cortical Studies by Dingle, Yu-Ting L, Boutin, Molly E, Chirila, Anda M, Livi, Liane L, Labriola, Nicholas R, Jakubek, Lorin M, Morgan, Jeffrey R, Darling, Eric M, Kauer, Julie A, Hoffman-Kim, Diane

“…There is a high demand for in vitro models of the central nervous system (CNS) to study neurological disorders, injuries, toxicity, and drug efficacy…”
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Controlling Mesenchymal Stem Cell Gene Expression Using Polymer-Mediated Delivery of siRNA by Benoit, Danielle S. W, Boutin, Molly E

“…siRNA treatment has great promise to specifically control gene expression and select cell behaviors but has delivery challenges limiting its use. Particularly…”
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Protein characterization of intracellular target-sorted, formalin-fixed cell subpopulations by Sadick, Jessica S., Boutin, Molly E., Hoffman-Kim, Diane, Darling, Eric M.

“…Cellular heterogeneity is inherent in most human tissues, making the investigation of specific cell types challenging. Here, we describe a novel,…”
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