Search Results - "Boutillon, C"

High-Resolution Magic Angle Spinning NMR Study of Resin-Bound Polyalanine Peptides by Warrass, R, Wieruszeski, J.-M, Boutillon, C, Lippens, G

“…Polyalanine sequences of varying length and tethered to a solid support are studied in atomic detail by high-resolution magic angle spinning (HR MAS) NMR. At…”
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Synthesis, folding, and structure of the β-turn mimic modified B1 domain of streptococcal protein G by ODAERT, BENOIT, JEAN, FABIENNE, BOUTILLON, CHRISTOPHE, BUISINE, ERIC, MELNYK, OLEG, TARTAR, ANDRE, LIPPENS, GUY

“…The mechanism of β-sheet formation remains a fundamental issue in our understanding of the protein folding process, but is hampered by the often encountered…”
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HRMAS NMR observation of β-sheet secondary structure on a water swollen solid support by Rousselot-Pailley, Pierre, Boutillon, Christophe, Wieruszeski, Jean-Michel, Lippens, Guy

“…In this paper HRMAS NMR was used to investigate whether peptides on a peptidyl resin swollen in aqueous solution can adopt an intramolecular β‐sheet structure…”
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Confronting the degeneracy of convergent combinatorial immunogens, or ‘mixotopes’, with the specificity of recognition of the target sequences by Gras-Masse, H., Boutillon, C., Diesis, E., Deprez, B., Tartar, A.

“…Immunization by convergent combinatorial peptide libraries, or ‘mixotopes’ represents an interesting approach for inducing broadly cross-reactive immune…”
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Association of synthetic peptide fragments of human apolipoprotein A-I with phospholipids by Vanloo, B, Demoor, L, Boutillon, C, Lins, L, Brasseur, R, Baert, J, Fruchart, J C, Tartar, A, Rosseneu, M

“…The sequences of the plasma apolipoproteins have a high degree of internal homology as they contain several 22-mer internal repeats. These amphipathic helical…”
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Combinatorial peptide library as an immunogen by Estaquier, J, Ameisen, J C, Auriault, C, Boutillon, C, Gras-Masse, H, Tartar, A

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Cuttlefish spermatid-specific protein T. Molecular characterization of two variants T1 and T2, putative precursors of sperm protamine variants Sp1 and Sp2 by D Wouters-Tyrou, M C Chartier-Harlin, A Martin-Ponthieu, C Boutillon, A Van Dorsselaer, P Sautière

“…In cuttlefish, as in selachians and mammals, spermiogenesis is characterized by the double nuclear protein transition histones---intermediate protein (protein…”
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The Chemical Shift Index method applied to resin-bound peptides by Fruchart, J.-S., Lippens, G., Warrass, R., Seetharaman, C., Dhalluin, C., Boutillon, C.

“…: The Chemical Shift Index (CSI) method proposed by Wishart et al. [Biochemistry (1992) 31, 1647–1651] to evaluate the secondary structure of peptides in…”
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Identification of T cell epitopes within a 23-kD antigen (P24) of Toxoplasma gondii by DUQUESNE, V, AURIAULT, C, GRAS-MASSE, H, BOUTILLON, C, DARCY, F, CESBRON, M.-F, TARTAR, D. A, CAPRON, A

“…Among the potentially vaccinating antigens, the products excreted/secreted by the parasite T. gondii have been demonstrated to be excellent candidates. The…”
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Amino acid sequence requirements for the epitope recognized by a monoclonal antibody reacting with the secreted antigen GP28.5 of Toxoplasma gondii by Cesbron-Delauw, M F, Boutillon, C, Mercier, C, Fourmaux, M P, Murray, A, Miquey, F, Tartar, A, Capron, A

“…We have characterized in detail, the epitope of the secreted antigen GP28.5 recognized by the mouse monoclonal antibody TG 17-179 using synthetic peptides and…”
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Comprehensive delineation of antigenic and immunogenic properties of peptides derived from the nef HIV-1 regulatory protein by Estaquier, J, Boutillon, C, Gras-Masse, H, Ameisen, J C, Capron, A, Tartar, A, Auriault, C

“…The Human Immunodeficiency Virus (HIV-1) nef regulatory protein, a protein involved in AIDS pathology, was used as a model to investigate and analyze B- and…”
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A simple reaction to produce small structurally complex and diverse molecules by Deprez-Poulain, Rebecca, Willand, Nicolas, Boutillon, Christophe, Nowogrocki, Guy, Azaroual, Nathalie, Deprez, Benoit

“…We describe the stereoselective synthesis of tricyclic lactams containing a chiral quaternary center and suitable for the synthesis of chemical libraries in…”
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Magic Angle Spinning Nuclear Magnetic Resonance in Solid-Phase Peptide Synthesis by Dhalluin, Christophe, Boutillon, Christophe, Tartar, André, Lippens, Guy

“…Solid-phase peptide synthesis of certain sequences (commonly called “difficult sequences”) suffers from the occurrence of incomplete coupling reactions and/or…”
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A synthetic protein corresponding to the entire vpr gene product from the human immunodeficiency virus HIV-1 is recognized by antibodies from HIV-infected patients by Gras-Masse, H, Ameisen, J C, Boutillon, C, Gesquière, J C, Vian, S, Neyrinck, J L, Drobecq, H, Capron, A, Tartar, A

“…The 95 amino acid-protein encoded by the non-structural vpr gene of the human immunodeficiency virus type 1 (LAV-1BRU isolate) was chemically synthesized by…”
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Preferential and persistent depletion of CCR5+T-helper lymphocytes with nonlymphoid homing potential despite early treatment of primary HIV infection by Krzysiek, Roman, Rudent, Annick, Bouchet-Delbos, Laurence, Foussat, Arnaud, Boutillon, Claudie, Portier, Alain, Ingrand, Didier, Sereni, Daniel, Galanaud, Pierre, Grangeot-Keros, Liliane, Emilie, Dominique

“…Strains of human immunodeficiency virus (HIV) transmitted between individuals use the CCR5 coreceptor, but no preferential depletion of particular…”
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Selective assay for CyPA and CyPB in human blood using highly specific anti-peptide antibodies by Allain, Fabrice, Boutillon, Christophe, Mariller, Christophe, Spik, Geneviève

“…Cyclophilins A and B (CyPA and CyPB) are known to be the main binding proteins for cyclosporin A (CsA), a potent immunosuppressive drug. Due to the high…”
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Synthetic vaccines and HIV-1 hypervariability: a "mixotope" approach by Gras-Masse, H, Ameisen, J C, Boutillon, C, Rouaix, F, Bossus, M, Deprez, B, Neyrinck, J L, Capron, A, Tartar, A

“…The hypervariability of the gp120 envelope protein principal neutralizing domain, the V3 loop, represents a major problem in the design of vaccines against…”
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Immunization of mice with lipopeptides bypasses the prerequisite for adjuvant. Immune response of BALB/c mice to human immunodeficiency virus envelope glycoprotein by Martinon, F, Gras-Masse, H, Boutillon, C, Chirat, F, Deprez, B, Guillet, JG, Gomard, E, Tartar, A, Levy, JP

“…In vivo priming of CTL requires the association with MHC class I molecules of peptides derived from the processing of endogenously produced proteins…”
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Comparative efficiency of simple lipopeptide constructs for in vivo induction of virus-specific CTL by Deprez, Benoît, Sauzet, Jean-Pierre, Boutillon, Christophe, Martinon, Frédéric, Tartar, André, Sergheraert, Christian, Guillet, Jean-Gérard, Gomard, Elisabeth, Gras-Masse, Hélène

“…We have previously shown that virus-specific CTL responses can be elicited in vivo by injecting, without adjuvant, 12–40 amino acid-long peptides, modified in…”
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Branched synthetic peptide constructs mimic cellular binding and efflux of apolipoprotein AI in reconstituted high density lipoproteins by Nion, Stéphane, Demoor, Ludovic, Boutillon, Christophe, Luchoomun, Jayraz, Vanloo, Berlinda, Fievet, Catherine, Castro, Graciela, Rosseneu, Maryvonne, Fruchart, Jean-Charles, Tartar, André, Clavey, Véronique

“…This study investigates the suitability of the trimeric apolipoprotein (apo) AI(145–183) peptide that we recently described, to serve as a model to probe the…”
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