Search Results - "Boutet, Agnès"

mTOR Signaling at the Crossroad between Metazoan Regeneration and Human Diseases by Lund-Ricard, Yasmine, Cormier, Patrick, Morales, Julia, Boutet, Agnès

“…A major challenge in medical research resides in controlling the molecular processes of tissue regeneration, as organ and structure damage are central to…”
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Digital Marine: An online platform for blended learning in a marine experimental biology module, the Schmid Training Course by Flom, Haley, Adamska, Maja, Lami, Raphaël, Gazave, Eve, D'Aniello, Salvatore, Schierwater, Bernd, Boutet, Agnès

“…For over 20 years, the Schmid Training Course (STC) has offered unique opportunities for marine biology students from European universities to learn about…”
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Snail activation disrupts tissue homeostasis and induces fibrosis in the adult kidney by Boutet, Agnès, De Frutos, Cristina A, Maxwell, Patrick H, Mayol, M José, Romero, J, Nieto, M Angela

“…During embryonic development, the kidney epithelium originates from cells that undergo a mesenchymal to epithelial transition (MET). The reverse process,…”
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eIF4B mRNA Translation Contributes to Cleavage Dynamics in Early Sea Urchin Embryos by Pontheaux, Florian, Boulben, Sandrine, Chassé, Héloïse, Boutet, Agnès, Roch, Fernando, Morales, Julia, Cormier, Patrick

“…During the first steps of sea urchin development, fertilization elicits a marked increase in protein synthesis essential for subsequent cell divisions. While…”
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The Roscoff Biological Station in the era of cellular and molecular biology: Focus on the 50 last years of research on marine animals by Cormier, Patrick, Boutet, Agnès, Colas, Pierre, Ruchaud, Sandrine, Bach, Stéphane, Thomas, Wilfried, Égée, Stéphane, Morales, Julia, Roch, Fernando

“…In the context of the 150th anniversary of the biological station of Roscoff, we describe here how cellular and molecular biology using marine metazoans has…”
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The ancestral role of nodal signalling in breaking L/R symmetry in the vertebrate forebrain by Lagadec, Ronan, Laguerre, Laurent, Menuet, Arnaud, Amara, Anis, Rocancourt, Claire, Péricard, Pierre, Godard, Benoît G., Celina Rodicio, Maria, Rodriguez-Moldes, Isabel, Mayeur, Hélène, Rougemont, Quentin, Mazan, Sylvie, Boutet, Agnès

“…Left-right asymmetries in the epithalamic region of the brain are widespread across vertebrates, but their magnitude and laterality varies among species…”
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The WTX/AMER1 gene family: evolution, signature and function by Boutet, Agnès, Comai, Glenda, Schedl, Andreas

“…WTX is a novel gene mutated in a proportion of Wilms' tumors and in patients suffering from sclerosing bone dysplasia. On the molecular level WTX has been…”
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The evolution of asymmetric photosensitive structures in metazoans and the Nodal connection by Boutet, Agnès

“…Asymmetries are observed in a great number of taxa in metazoans. More particularly, functional lateralization and neuroanatomical asymmetries within the…”
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A knock‐in mouse line conditionally expressing the tumor suppressor WTX/AMER1 by Boutet, Agnès, Comai, Glenda, Charlet, Aurélie, Jian Motamedi, Fariba, Dhib, Haroun, Bandiera, Roberto, Schedl, Andreas

“…Summary WTX/AMER1 is an important developmental regulator, mutations in which have been identified in a proportion of patients suffering from the renal…”
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Reactivation of Snail Genes in Renal Fibrosis and Carcinomas: A Process of Reversed Embryogenesis? by Boutet, Agnès, Esteban, Miguel, Maxwell, Patrick H., Nieto, M. Angela

“…While the activity of Snail genes is required during embryonic development for the formation of different tissues and organs, they must be repressed in the…”
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Snail1-induced partial epithelial-to-mesenchymal transition drives renal fibrosis in mice and can be targeted to reverse established disease by Grande, M Teresa, Sánchez-Laorden, Berta, López-Blau, Cristina, De Frutos, Cristina A, Boutet, Agnès, Arévalo, Miguel, Rowe, R Grant, Weiss, Stephen J, López-Novoa, José M, Nieto, M Angela

“…During renal fibrosis, epithelial cells undergo a partial epithelial-to-mesenchymal transition that can be targeted to reverse established disease. Progressive…”
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Cellular expression of functional chemokine receptor CCR5 and CXCR4 in human embryonic neurons by Boutet, Agnès, Salim, Hassan, Leclerc, Philippe, Tardieu, Marc

“…In the present study we analysed expression of the chemokine receptors CCR5 and CXCR4 in human embryonic neurons. Both receptors were detected in neurons from…”
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Genetic and Molecular Insights Into Genotype‐Phenotype Relationships in Osteopathia Striata With Cranial Sclerosis (OSCS) Through the Analysis of Novel Mouse Wtx Mutant Alleles by Comai, Glenda, Boutet, Agnès, Tanneberger, Kristina, Massa, Filippo, Rocha, Ana‐Sofia, Charlet, Aurelie, Panzolini, Clara, Jian Motamedi, Fariba, Brommage, Robert, Hans, Wolfgang, Funck‐Brentano, Thomas, Hrabe de Angelis, Martin, Hartmann, Christine, Cohen‐Solal, Martine, Behrens, Jürgen, Schedl, Andreas

“…ABSTRACT The X‐linked WTX/AMER1 protein constitutes an important component of the β‐catenin destruction complex that can both enhance and suppress canonical…”
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Mechanisms of endoderm formation in a cartilaginous fish reveal ancestral and homoplastic traits in jawed vertebrates by Godard, Benoit G, Coolen, Marion, Le Panse, Sophie, Gombault, Aurélie, Ferreiro-Galve, Susana, Laguerre, Laurent, Lagadec, Ronan, Wincker, Patrick, Poulain, Julie, Da Silva, Corinne, Kuraku, Shigehiro, Carre, Wilfrid, Boutet, Agnès, Mazan, Sylvie

“…In order to gain insight into the impact of yolk increase on endoderm development, we have analyzed the mechanisms of endoderm formation in the catshark S…”
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Erratum: Snail1-induced partial epithelial-to-mesenchymal transition drives renal fibrosis in mice and can be targeted to reverse established disease by Grande, M Teresa, Sánchez-Laorden, Berta, López-Blau, Cristina, De Frutos, Cristina A, Boutet, Agnès, Arévalo, Miguel, Rowe, R Grant, Weiss, Stephen J, López-Novoa, José M, Nieto, M Angela

“…Nat. Med. 21, 989–997 (2015); published online 03 August 2015; corrected after print 4 September 2015 In the version of this article initially published, the…”
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Differential regulation of gelatinase A and B and TIMP-1 and -2 by TNFα and HIV virions in astrocytes by Lévêque, Thierry, Le Pavec, Gwenaëlle, Boutet, Agnès, Tardieu, Marc, Dormont, Dominique, Gras, Gabriel

“…Changes in the fine balance between matrix metalloproteinases and their tissue inhibitors, which drives extracellular matrix turnover, may be critical to…”
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Slow cycling cells in the continuous dental lamina of Scyliorhinus canicula: new evidence for stem cells in sharks by Vandenplas, Sam, Vandeghinste, Robbe, Boutet, Agnes, Mazan, Sylvie, Huysseune, Ann

“…In the lesser spotted catshark (Scyliorhinus canicula), as in most non-mammalian vertebrates, the dentition renews throughout life. To contribute to our…”
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Expression patterns of the Wtx/Amer gene family during mouse embryonic development by Comai, Glenda, Boutet, Agnes, Neirijnck, Yasmine, Schedl, Andreas

“…WTX/AMER1 is a novel negative regulator of the WNT/β‐catenin pathway with mutations detected in Wilms' tumors and an X‐linked sclerosing bone dysplasia…”
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The "Snail" genes and renal diseases: what we learn from organogenesis by Boutet, Agnès, Nieto, M Angela

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Isolated human astrocytes are not susceptible to infection by M- and T-tropic HIV-1 strains despite functional expression of the chemokine receptors CCR5 and CXCR4 by Boutet, Agnès, Salim, Hassan, Taoufik, Yassine, Lledo, Pierre-Marie, Vincent, Jean-Didier, Delfraissy, Jean-François, Tardieu, Marc

“…Within the brain, HIV‐1 targets the microglia and astrocytes. Previous studies have reported that viral entry into astrocytes is independent of CD4, in…”
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