Search Results - "Boutelle, Martyn"

Measurement of Electrophysiological Signals In Vitro Using High‐Performance Organic Electrochemical Transistors by Tyrrell, James E., Boutelle, Martyn G., Campbell, Alasdair J.

“…Biological environments use ions in charge transport for information transmission. The properties of mixed electronic and ionic conductivity in organic…”
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Monitoring biomolecule concentrations in tissue using a wearable droplet microfluidic-based sensor by Nightingale, Adrian M., Leong, Chi Leng, Burnish, Rachel A., Hassan, Sammer-ul, Zhang, Yu, Clough, Geraldine F., Boutelle, Martyn G., Voegeli, David, Niu, Xize

“…Knowing how biomarker levels vary within biological fluids over time can produce valuable insight into tissue physiology and pathology, and could inform…”
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Fiber-Based Electrochemical Biosensors for Monitoring pH and Transient Neurometabolic Lactate by Booth, Marsilea A, Gowers, Sally A. N, Hersey, Melinda, Samper, Isabelle C, Park, Seongjun, Anikeeva, Polina, Hashemi, Parastoo, Stevens, Molly M, Boutelle, Martyn G

“…Developing tools that are able to monitor transient neurochemical dynamics is important to decipher brain chemistry and function. Multifunctional polymer-based…”
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3D Printed Microfluidic Device with Integrated Biosensors for Online Analysis of Subcutaneous Human Microdialysate by Gowers, Sally A. N, Curto, Vincenzo F, Seneci, Carlo A, Wang, Chu, Anastasova, Salzitsa, Vadgama, Pankaj, Yang, Guang-Zhong, Boutelle, Martyn G

“…This work presents the design, fabrication, and characterization of a robust 3D printed microfluidic analysis system that integrates with FDA-approved clinical…”
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Real-Time Non-Invasive Imaging and Detection of Spreading Depolarizations through EEG: An Ultra-Light Explainable Deep Learning Approach by Wu, Yinzhe, Jewell, Sharon, Xing, Xiaodan, Nan, Yang, Strong, Anthony J., Yang, Guang, Boutelle, Martyn G.

“…A core aim of neurocritical care is to prevent secondary brain injury. Spreading depolarizations (SDs) have been identified as an important independent cause…”
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Organic Electrochemical Transistor Common‐Source Amplifier for Electrophysiological Measurements by Tyrrell, James E., Petkos, Konstantinos, Drakakis, Emmanuel M., Boutelle, Martyn G., Campbell, Alasdair J.

“…The portability of physiological monitoring has necessitated the biocompatibility of components used in circuitry local to biological environments. A key…”
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Evaluation of a minimally invasive glucose biosensor for continuous tissue monitoring by Sharma, Sanjiv, Huang, Zhenyi, Rogers, Michelle, Boutelle, Martyn, Cass, Anthony E. G.

“…We describe here a minimally invasive glucose biosensor based on a microneedle array electrode fabricated from an epoxy-based negative photoresist (SU8 50) and…”
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What Should a Clinician Do When Spreading Depolarizations are Observed in a Patient? by Helbok, Raimund, Hartings, Jed A., Schiefecker, Alois, Balança, Baptiste, Jewel, Sharon, Foreman, Brandon, Ercole, Ari, Balu, Ramani, Ayata, Cenk, Ngwenya, Laura, Rosenthal, Eric, Boutelle, Martyn G., Farkas, Eszter, Dreier, Jens P., Fabricius, Martin, Shuttleworth, C. William, Carlson, Andrew

“…The International Conference on Spreading Depolarizations (iCSD) held in Boca Raton, Florida, in the September of 2018 devoted a section to address the…”
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Analytical science in neurochemistry by Masson, Jean-Francois, Hashemi, Parastoo, Boutelle, Martyn G

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Ultrasensitive Detection of Dopamine Using a Carbon Nanotube Network Microfluidic Flow Electrode by Sansuk, Siriwat, Bitziou, Eleni, Joseph, Maxim B, Covington, James A, Boutelle, Martyn G, Unwin, Patrick R, Macpherson, Julie V

“…The electrochemical measurement of dopamine (DA), in phosphate buffer solution (pH 7.4), with a limit of detection (LOD) of ∼5 pM in 50 μL (∼ 250 attomol) is…”
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Consensus statement from the 2014 International Microdialysis Forum by Hutchinson, Peter J., Jalloh, Ibrahim, Helmy, Adel, Carpenter, Keri L. H., Rostami, Elham, Bellander, Bo-Michael, Boutelle, Martyn G., Chen, Jeff W., Claassen, Jan, Dahyot-Fizelier, Claire, Enblad, Per, Gallagher, Clare N., Helbok, Raimund, Hillered, Lars, Le Roux, Peter D., Magnoni, Sandra, Mangat, Halinder S., Menon, David K., Nordström, Carl-Henrik, O’Phelan, Kristine H., Oddo, Mauro, Perez Barcena, Jon, Robertson, Claudia, Ronne-Engström, Elisabeth, Sahuquillo, Juan, Smith, Martin, Stocchetti, Nino, Belli, Antonio, Carpenter, T. Adrian, Coles, Jonathan P., Czosnyka, Marek, Dizdar, Nil, Goodman, J. Clay, Gupta, Arun K., Nielsen, Troels H., Marklund, Niklas, Montcriol, Ambroise, O’Connell, Mark T., Poca, Maria A., Sarrafzadeh, Asita, Shannon, Richard J., Skjøth-Rasmussen, Jane, Smielewski, Peter, Stover, John F., Timofeev, Ivan, Vespa, Paul, Zavala, Elizabeth, Ungerstedt, Urban

“…Microdialysis enables the chemistry of the extracellular interstitial space to be monitored. Use of this technique in patients with acute brain injury has…”
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Simultaneous monitoring of potassium, glucose and lactate during spreading depolarization in the injured human brain – Proof of principle of a novel real-time neurochemical analysis system, continuous online microdialysis by Rogers, Michelle L, Leong, Chi Leng, Gowers, Sally AN, Samper, Isabelle C, Jewell, Sharon L, Khan, Asma, McCarthy, Leanne, Pahl, Clemens, Tolias, Christos M, Walsh, Daniel C, Strong, Anthony J, Boutelle, Martyn G

“…Spreading depolarizations occur spontaneously and frequently in injured human brain. They propagate slowly through injured tissue often cycling around a local…”
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A shortened surface electromyography recording is sufficient to facilitate home fasciculation assessment by Crook‐Rumsey, Mark, Musa, Abdi Malik, Iniesta, Raquel, Drakakis, Emmanuel, Boutelle, Martyn G., Shaw, Christopher E., Bashford, James

“…Introduction/Aims Fasciculations are an early clinical hallmark of amyotrophic lateral sclerosis (ALS), amenable to detection by high‐density surface…”
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A High‐Performance Application Specific Integrated Circuit for Electrical and Neurochemical Traumatic Brain Injury Monitoring by Pagkalos, Ilias, Rogers, Michelle L., Boutelle, Martyn G., Drakakis, Emmanuel M.

“…This paper presents the first application specific integrated chip (ASIC) for the monitoring of patients who have suffered a Traumatic Brain Injury (TBI). By…”
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First‐recruited motor units adopt a faster phenotype in amyotrophic lateral sclerosis by Weddell, Thomas, Bashford, James, Wickham, Aidan, Iniesta, Raquel, Chen, Maoqi, Zhou, Ping, Drakakis, Emmanuel, Boutelle, Martyn, Mills, Kerry, Shaw, Chris

“…Key points Amyotrophic lateral sclerosis (ALS) is an incurable neurodegenerative disorder of motor neurons, carrying a short survival. High‐density motor unit…”
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3D printed microfluidic device for online detection of neurochemical changes with high temporal resolution in human brain microdialysate by Samper, Isabelle C, Gowers, Sally A N, Rogers, Michelle L, Murray, De-Shaine R K, Jewell, Sharon L, Pahl, Clemens, Strong, Anthony J, Boutelle, Martyn G

“…This paper presents the design, optimisation and fabrication of a mechanically robust 3D printed microfluidic device for the high time resolution online…”
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Clinical translation of microfluidic sensor devices: focus on calibration and analytical robustness by Gowers, Sally A N, Rogers, Michelle L, Booth, Marsilea A, Leong, Chi L, Samper, Isabelle C, Phairatana, Tonghathai, Jewell, Sharon L, Pahl, Clemens, Strong, Anthony J, Boutelle, Martyn G

“…We present approaches to facilitate the use of microfluidics outside of the laboratory, in our case within a clinical setting and monitoring from human…”
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Portable Microfluidic Biosensing System for Real-Time Analysis of Microdialysate in Transplant Kidneys by Samper, Isabelle C, Gowers, Sally A. N, Booth, Marsilea A, Wang, Chu, Watts, Thomas, Phairatana, Tonghathai, Vallant, Natalie, Sandhu, Bynvant, Papalois, Vassilios, Boutelle, Martyn G

“…Currently, there is a severe shortage of donor kidneys that are fit for transplantation, due in part to a lack of adequate viability assessment tools for…”
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The military applications of physiological sensors by Khan, Mansoor, Boutelle, Martyn

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Dynamic metabolic response to multiple spreading depolarizations in patients with acute brain injury: an online microdialysis study by Feuerstein, Delphine, Manning, Andrew, Hashemi, Parastoo, Bhatia, Robin, Fabricius, Martin, Tolias, Christos, Pahl, Clemens, Ervine, Max, Strong, Anthony J, Boutelle, Martyn G

“…Spreading depolarizations (SDs) occur spontaneously with high incidence in patients with acute brain injury. They can be detected by subdural…”
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