Search Results - "Boutard, P."

NOTCH1 and FBXW7 mutations have a favorable impact on early response to treatment, but not on outcome, in children with T-cell acute lymphoblastic leukemia (T-ALL) treated on EORTC trials 58881 and 58951 by Clappier, E, Collette, S, Grardel, N, Girard, S, Suarez, L, Brunie, G, Kaltenbach, S, Yakouben, K, Mazingue, F, Robert, A, Boutard, P, Plantaz, D, Rohrlich, P, van Vlierberghe, P, Preudhomme, C, Otten, J, Speleman, F, Dastugue, N, Suciu, S, Benoit, Y, Bertrand, Y, Cavé, H

“…Risk-adjusted treatment stratification in T-cell acute lymphoblastic leukemias (T-ALLs) is currently based only on early response to chemotherapy. We…”
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Characteristics of endobronchial primitive tumors in children by Eyssartier, E., Ang, P., Bonnemaison, E., Gibertini, I., Diot, P., Carpentier, E., Chantepie, A., Leclair, M.D., Brouard, J., Boutard, P., Deneuville, E., Marie-Cardine, A., Lardy, H.

“…Summary Primary endobronchial tumors are rare in children and they include a broad spectrum of lesions. The aim of this study was to determine the…”
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Long-term results of three randomized trials (58831, 58832, 58881) in childhood acute lymphoblastic leukemia : a CLCG-EORTC report by VILMER, E, SUCIU, S, MANEL, A.-M, ROBERT, A, NELKEN, B, MILLOT, F, LUTZ, P, RIALLAND, X, MECHINAUD, F, BOUTARD, P, BEHAR, C, CHANTRAINE, J-M, FERSTER, A, PLOUVIER, E, LAUREYS, G, BROCK, P, UYTTEBROECK, A, MARGUERITTE, G, PLANTAZ, D, NORTON, L, FRANCOTTE, N, GYSELINCK, J, WATERKEYN, C, BERTRAND, Y, SOLBU, G, PHILIPPE, N, OTTEN, J, CAVE, H, THYSS, A, BENOIT, Y, DASTUGUE, N, FOURNIER, M, SOUILLET, G

“…We present here the long-term results of three randomized clinical trials conducted on children with newly diagnosed acute lymphoblastic leukemia (ALL) between…”
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Infectious diseases in the first year of life, perinatal characteristics and childhood acute leukaemia by JOURDAN-DA SILVA, N, PEREL, Y, ROBERT, A, ARMARI, C, MUNZER, M, MILLOT, F, DE LUMLEY, L, BERTHOU, C, RIALLAND, X, PAUTARD, B, HEMON, D, CLAVEL, J, MECHINAUD, F, PLOUVIER, E, GANDEMER, V, LUTZ, P, VANNIER, J. P, LAMAGNERE, J. L, MARGUERITTE, G, BOUTARD, P

“…The objective of the present study was to investigate the role of early common infections and perinatal characteristics in the aetiology of childhood common…”
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Results of 58872 and 58921 trials in acute myeloblastic leukemia and relative value of chemotherapy vs allogeneic bone marrow transplantation in first complete remission: the EORTC Children Leukemia Group report by Entz-Werle, N, Suciu, S, van der Werff ten Bosch, J, Vilmer, E, Bertrand, Y, Benoit, Y, Margueritte, G, Plouvier, E, Boutard, P, Vandecruys, E, Ferster, A, Lutz, P, Uyttebroeck, A, Hoyoux, C, Thyss, A, Rialland, X, Norton, L, Pages, M-P, Philippe, N, Otten, J, Behar, C

“…The first EORTC (European Organization of Research and Treatment of Cancer) acute myeloblastic leukemia (AML) pilot study (58872) was conducted between January…”
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Mature B-cell lymphoblastic leukemia with MLL rearrangement: an uncommon and distinct subset of childhood acute leukemia by Blin, N, Méchinaud, F, Talmant, P, Garand, R, Boutard, P, Dastugue, N, McIntyre, E A, Harousseau, J L, Avet-Loiseau, H

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Childhood secondary ALL after ALL treatment by ZUNA, J, CAVD, H, BOUTARD, P, SCHRAUDER, A, STERBA, J, MARSCHALEK, R, VAN DONGEN, J. J. M, HRUSAK, O, STARY, J, TRKA, J, ECKERT, C, SZCZEPANSKI, T, MEYER, C, MEJSTRIKOVA, E, FRONKOVA, E, MUZIKOVA, K, CLAPPIER, E, MENDELOVA, D

“…Data on secondary acute lymphoblastic leukaemia (sALL) following ALL treatment are very rare. However, the incidence might be underestimated as sALLs without a…”
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Granulocyte Colony-Stimulating Factor in Induction Treatment of Children With Non-Hodgkin’s Lymphoma: A Randomized Study of the French Society of Pediatric Oncology by PATTE, C, LAPLANCHE, A, BERTOZZI, A. I, BARUCHEL, A, FRAPPAZ, D, SCHMITT, C, MECHINAUD, F, NELKEN, B, BOUTARD, P, MICHON, J

“…To determine whether granulocyte colony-stimulating factor (G-CSF; lenograstim) decreases the incidence of febrile neutropenia after induction courses in…”
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Value of High-Dose Cytarabine During Interval Therapy of a Berlin-Frankfurt-Munster–Based Protocol in Increased-Risk Children With Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma: Results of the European Organization for Research and Treatment of Cancer 58881 Randomized Phase III Trial by MILLOT, F, SUCIU, S, MARGUERITE, G, FERSTER, A, PLOUVIER, E, RIALLAND, X, BEHARD, C, PLANTAZ, D, DRESSE, M. F, PHILIPPET, P, NORTON, L, THYSS, A, PHILIPPE, N, DASTUGUE, N, WATERKEYN, C, VILMER, E, OTTEN, J, BENOIT, Y, MAZINGUE, F, UYTTEBROECK, A, LUTZ, P, MECHINAUD, F, ROBERT, A, BOUTARD, P

“…The European Organization for Research and Treatment of Cancer 58881 study was designed to test in a prospective multicentric randomized trial the value of…”
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Value of intravenous 6-mercaptopurine during continuation treatment in childhood acute lymphoblastic leukemia and non-Hodgkin's lymphoma: final results of a randomized phase III trial (58881) of the EORTC CLG by VAN DER WERFF TEN BOSCH, J, SUCIU, S, FERSTER, A, PLOUVIER, E, MAES, P, MUNZER, M, PLANTAZ, D, DRESSE, M.-F, PHILIPPET, P, SIRVENT, N, WATERKEYN, C, VILMER, E, THYSS, A, PHILIPPE, N, OTTEN, J, BERTRAND, Y, NORTON, L, MAZINGUE, F, UYTTEBROECK, A, LUTZ, P, ROBERT, A, BOUTARD, P

“…Between November 1990 and November 1996, EORTC Children Leukemia Group conducted a randomized trial in de novo acute lymphoblastic leukemia and lymphoblastic…”
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High-dose melphalan, etoposide, and carboplatin followed by autologous stem-cell rescue in pediatric high-risk recurrent Wilms' tumor: a French Society of Pediatric Oncology study by Pein, F, Michon, J, Valteau-Couanet, D, Quintana, E, Frappaz, D, Vannier, J P, Philip, T, Bergeron, C, Baranzelli, M C, Thyss, A, Stephan, J L, Boutard, P, Gentet, J C, Zucker, J M, Tournade, M F, Hartmann, O

“…The three-drug combination of melphalan (M), etoposide (E), and carboplatin (C) followed by autologous stem-cell (ASC) rescue has been evaluated prospectively…”
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Genetic alterations in primary osteosarcoma from 54 children and adolescents by targeted allelotyping by ENTZ-WERLE, N, SCHNEIDER, A, MEYER, N, GAUB, M-P, LUTZ, P, BABIN, A, OUDET, P, KALIFA, C, VOEGELI, A-C, TABONE, M-D, MAREC-BERARD, P, MARCELLIN, L, PACQUEMENT, H, TERRIER, P, BOUTARD, P

“…At present, the only recognised prognostic factor for primary osteosarcoma is the histological response to preoperative chemotherapy. Our study was designed to…”
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Adverse outcome of infants with metastatic neuroblastoma, MYCN amplification and/or bone lesions: results of the French Society of Pediatric Oncology by MINARD, V, HARTMANN, O, LEVERGER, G, STEPHAN, J. L, THYSS, A, CHASTAGNER, P, COUILLAULT, G, DEVALCK, C, LUTZ, P, MECHINAUD, F, MILLOT, F, PLANTAZ, D, PEYROULET, M. C, RIALLAND, X, RUBIE, H, MICHON, J, COZE, C, DEFACHELLE, A. S, LEJARS, O, PEREL, Y, BERGERON, C, BOUTARD, P

“…To assess the relevance of MYCN amplification and bone lesions in stage 4 neuroblastoma (NB) in infants aged <1 year, 51 infants with stage 4 NB were enrolled…”
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High-dose thiotepa and hematopoietic stem cell transplantation in pediatric malignant mesenchymal tumors : a phase II study by LAFAY-COUSIN, L, HARTMANN, O, PLOUVIER, P, MECHINAUD, F, BOUTARD, P, OBERLIN, O

“…The prognosis of metastatic malignant mesenchymal tumors (MMT) remains poor. Given the chemosensitivity of these neoplasms, a phase II study of high-dose…”
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Deletion of chromosomal region 13q14.3 in childhood acute lymphoblastic leukemia by CAVE, H, AVET-LOISEAU, H, DEVAUX, I, RONDEAU, G, BOUTARD, P, LEBRUN, E, MECHINAUD, F, VILMER, E, GRANDCHAMP, B

“…Deletion of the 13q14 chromosomal region is frequent in B cell chronic lymphocytic leukemia (B-CLL) and is believed to inactivate a tumor supressor gene (TSG)…”
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A European phase II study of recombinant human granulocyte colony-stimulating factor (lenograstim) in the treatment of severe chronic neutropenia in children by DONADIEU, J, BOUTARD, P, BERNATOWSKA, E, TCHERNIA, G, COUILLAUD, G, PHILIPPE, N, LE GALL, E

“…We conducted a multicentre, open-label prospective study to evaluate the efficacy and tolerability of lenograstim (human-identical glycosylated rHuG-CSF) in…”
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Etoposide and carboplatin: a highly effective combination in relapsed or refractory Wilms' tumor--a phase II study by the French Society of Pediatric Oncology by Pein, F, Tournade, M F, Zucker, J M, Brunat-Mentigny, M, Deville, A, Boutard, P, Dusol, F, Gentet, J C, Legall, E, Mechinaud, F

“…Since we had previously demonstrated encouraging efficacy of etoposide in patients with relapsed or refractory Wilms' tumor (WT), the likely synergism between…”
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Classification of and risk factors for hematologic complications in a French national cohort of 102 patients with Shwachman-Diamond syndrome by DONADIEU, Jean, FENNETEAU, Odile, PEROT, Christine, MICHEL, Gérard, FOUYSSAC, Fanny, PAILLARD, Catherine, GANDEMER, Virginie, BOUTARD, Patrick, SCHMITZ, Jacques, MORALI, Alain, LEBLANC, Thierry, BELLANNE-CHANTELOT, Christine, BEAUPAIN, Blandine, BEAUFILS, Sandrine, BELLANGER, Florence, MAHLAOUI, Nizar, LAMBILLIOTTE, Anne, ALADJIDI, Nathalie, BERTRAND, Yves, MIALOU, Valérie

“…Patients with the Shwachman-Diamond syndrome often develop hematologic complications. No risk factors for these complications have so far been identified. The…”
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Virus recovery from stools of patients undergoing bone marrow transplantation by Troussard, X, Bauduer, F, Gallet, E, Freymuth, F, Boutard, P, Ballet, J J, Reman, O, Leporrier, M

“…Diarrhea in marrow transplant recipients is a frequent complication attributable to non-infectious events such as acute GVHD or infectious events such as viral…”
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Treatment outcome in infant acute lymphoblastic leukemia by Ferster, Alina, Benoit, Yves, Francotte, Nadine, Dresse, Marie-Françoise, Uyttebroeck, Anne, Plouvier, Emmanuel, Thyss, Antoine, Lutz, Patrick, Marguerite, Geneviève, Behar, Catherine, Mazingue, Françoise, Boutard, Patrick, Millot, Frederic, Rialland, Xavier, Mechinaud, Françoise, Norton, Lucilia, Robert, Alain, Otten, Jacques, Vilmer, Etienne, Philippe, Noel, Waterkeyn, Christine, Suciu, Stefan

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