Search Results - "Boussios, Stergios"
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Frontiers of Ovarian Carcinosarcoma
Published in Current treatment options in oncology (01-12-2023)“…Opinion statement Ovarian carcinosarcoma (OCS), also known as a malignant mixed Müllerian tumour (MMMT), is a rare and aggressive form of cancer that accounts…”
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Aberrations of DNA Repair Pathways in Prostate Cancer-The State of the Art
Published in International journal of molecular sciences (21-02-2023)“…Prostate cancer (PC) is the second most commonly diagnosed cancer in males worldwide and the fifth most common cause of cancer-related death in men [...]…”
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BRCA Mutations in Prostate Cancer: Assessment, Implications and Treatment Considerations
Published in International journal of molecular sciences (23-11-2021)“…Prostate cancer ranks fifth in cancer-related mortality in men worldwide. DNA damage is implicated in cancer and DNA damage response (DDR) pathways are in…”
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Genetic Aberrations of DNA Repair Pathways in Prostate Cancer: Translation to the Clinic
Published in International journal of molecular sciences (10-09-2021)“…Prostate cancer (PC) is the second most common cancer in men worldwide. Due to the large-scale sequencing efforts, there is currently a better understanding of…”
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Advances in Ovarian Cancer Treatment Beyond PARP Inhibitors
Published in Current cancer drug targets (01-01-2023)“…Ovarian cancer has become the largest cause of gynaecological cancer-related mortality. It is typically diagnosed at a late stage and has no effective…”
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Frontiers of Molecular Biology of Cancer
Published in International journal of molecular sciences (06-12-2023)“…Cancer is rooted in genetic background, with the expression of oncogenesis playing a pivotal role in the early stages of tumor formation [...]…”
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HPV and Cervical Cancer: A Review of Epidemiology and Screening Uptake in the UK
Published in Pathogens (Basel) (01-02-2023)“…Cervical cancer is the fourth most common malignancy in females worldwide, and a leading cause of death in the United Kingdom (UK). The human papillomavirus…”
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Androgen Receptor Gene Pathway Upregulation and Radiation Resistance in Oligometastatic Prostate Cancer
Published in International journal of molecular sciences (26-04-2022)“…Stereotactic ablative body radiotherapy (SABR) is currently used as a salvage intervention for men with oligometastatic prostate cancer (PC), and increasingly…”
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State-of-the-Art Molecular Oncology in UK
Published in International journal of molecular sciences (26-05-2023)“…Molecular oncology is a rapidly evolving field that focuses on the genetic and molecular basis of cancer [...]…”
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Veliparib in ovarian cancer: a new synthetically lethal therapeutic approach
Published in Investigational new drugs (01-02-2020)“…Summary Epithelial ovarian cancer (EOC) accounts for nearly 90% of all ovarian malignancies. The standard therapeutic strategy includes cytoreductive surgery…”
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Poly (ADP-Ribose) Polymerase Inhibitors: Talazoparib in Ovarian Cancer and Beyond
Published in Drugs in R&D (01-06-2020)“…Genetic complexity and DNA damage repair defects are common in different cancer types and can induce tumor-specific vulnerabilities. Poly(ADP-ribose)…”
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Angiogenesis and Anti-Angiogenic Treatment in Prostate Cancer: Mechanisms of Action and Molecular Targets
Published in International journal of molecular sciences (14-09-2021)“…Prostate cancer (PC) is the most common cancer in men and the second leading cause of cancer-related death worldwide. Many therapeutic advances over the last…”
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Applications of Proteomics in Ovarian Cancer: Dawn of a New Era
Published in Proteomes (09-05-2022)“…The ability to identify ovarian cancer (OC) at its earliest stages remains a challenge. The patients present an advanced stage at diagnosis. This heterogeneous…”
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Combined Strategies with Poly (ADP-Ribose) Polymerase (PARP) Inhibitors for the Treatment of Ovarian Cancer: A Literature Review
Published in Diagnostics (Basel) (01-08-2019)“…Poly (ADP-ribose) polymerase (PARP) inhibitors are the first clinically approved drugs designed to exploit synthetic lethality, and were first introduced as a…”
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An Update on the Prognostic and Predictive Serum Biomarkers in Metastatic Prostate Cancer
Published in Diagnostics (Basel) (31-07-2020)“…Serum biomarkers are molecules produced by normal and abnormal cells. Prostate specific antigen (PSA) is an example of a serum biomarker used widely in the…”
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Exosomes in the Diagnosis and Treatment of Renal Cell Cancer
Published in International journal of molecular sciences (01-09-2023)“…Renal cell carcinoma (RCC) is the most prevalent type of kidney cancer originating from renal tubular epithelial cells, with clear cell RCC comprising…”
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Predictive biomarkers for immune checkpoint inhibitor response in urothelial cancer
Published in Therapeutic Advances in Medical Oncology (01-01-2023)“…Immune checkpoint inhibitors (ICIs) are commonly used to treat patients with advanced urothelial cancer. However, a significant number of patients do not…”
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Exosomes in Renal Cell Cancer: Diagnostic and Therapeutic Nanovehicles
Published in Technology in cancer research & treatment (01-01-2024)“…Early diagnosis is crucial for enhancing the survival rate of renal cell cancer patients, and exosomes present potential advantages in this area. Their small…”
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The Developing Story of Predictive Biomarkers in Colorectal Cancer
Published in Journal of personalized medicine (07-02-2019)“…Colorectal cancer (CRC) is the third most common malignancy worldwide. Surgery remains the most important treatment for non-metastatic CRC, and the…”
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Large Language Models in Oncology: Revolution or Cause for Concern?
Published in Current oncology (Toronto) (01-04-2024)“…The technological capability of artificial intelligence (AI) continues to advance with great strength. Recently, the release of large language models has taken…”
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