Search Results - "Bourrié, B"

Activation of mitogen-activated protein kinases by stimulation of the central cannabinoid receptor CB1 by Bouaboula, M, Poinot-Chazel, C, Bourrié, B, Canat, X, Calandra, B, Rinaldi-Carmona, M, Le Fur, G, Casellas, P

“…The G-protein-coupled central cannabinoid receptor (CB1) has been shown to be functionally associated with several biological responses including inhibition of…”
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Stimulation of Cannabinoid Receptor CB1 Induces krox-24 Expression in Human Astrocytoma Cells by Bouaboula, Monsif, Bourrié, Bernard, Rinaldi-Carmona, Murielle, Shire, David, Fur, Gérard Le, Casellas, Pierre

“…The recent isolation and cloning of the G protein-coupled central cannabinoid receptor (CB1) from brain tissue has provided a molecular basis to elucidate how…”
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In vivo inhibition of endotoxin-induced pro-inflammatory cytokines production by the sigma ligand SR 31747 by Derocq, J M, Bourrié, B, Ségui, M, Le Fur, G, Casellas, P

“…In previous studies, the authors demonstrated that the new sigma ligand, cis-N-cyclohexyl-N-ethyl-3-(3-chloro-4-cyclohexyl-phenyl) propen-2-ylamine…”
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N-Heterocyclic Carbene-Amine Pt(II) Complexes, a New Chemical Space for the Development of Platinum-Based Anticancer Drugs by Skander, Myriem, Retailleau, Pascal, Bourrié, Bernard, Schio, Laurent, Mailliet, Patrick, Marinetti, Angela

“…N-Heterocyclic carbene (NHC) platinum complexes have been highlighted as a promising and original platform for building new cytotoxic drugs of the cisplatin…”
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Effect of a new, potent, non-peptide V1a vasopressin antagonist, SR 49059, on the binding and the mitogenic activity of vasopressin on Swiss 3T3 cells by Serradeil-Le Gal, C, Bourrié, B, Raufaste, D, Carayon, P, Garcia, C, Maffrand, J P, Le Fur, G, Casellas, P

“…The effects of SR 49059, a new non-peptide, selective arginine vasopressin (AVP), V1a antagonist, were investigated both on AVP's receptors and on the…”
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Immunopharmacological profile of SR 31747: in vitro and in vivo studies on humoral and cellular responses by Casellas, P, Bourrié, B, Canat, X, Carayon, P, Buisson, I, Paul, R, Brelière, J C, Le Fur, G

“…In our preceding paper, we demonstrated that both human and rat lymphocytes possess saturable high-affinity binding sites for the new sigma ligand SR 31747…”
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SR31747A is a sigma receptor ligand exhibiting antitumoural activity both in vitro and in vivo by BERTHOIS, Y, BOURRIE, B, GALIEGUE, S, VIDAL, H, CARAYON, P, MARTIN, P. M, CASELLAS, P

“…SR31747A is a recently described sigma receptor ligand that binds SR31747A-binding protein 1 (SR-BP) and emopamil-binding protein (EBP) (also called the sigma…”
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Purification and characterization of the human SR 31747A-binding protein. A nuclear membrane protein related to yeast sterol isomerase by Jbilo, O, Vidal, H, Paul, R, De Nys, N, Bensaid, M, Silve, S, Carayon, P, Davi, D, Galiègue, S, Bourrié, B, Guillemot, J C, Ferrara, P, Loison, G, Maffrand, J P, Le Fur, G, Casellas, P

“…SR 31747A, defined as a sigma ligand, is a novel immunosuppressive agent that blocks proliferation of human and mouse lymphocytes. Using a radiolabeled…”
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Signaling pathway associated with stimulation of CB2 peripheral cannabinoid receptor. Involvement of both mitogen-activated protein kinase and induction of Krox-24 expression by Bouaboula, M, Poinot-Chazel, C, Marchand, J, Canat, X, Bourrié, B, Rinaldi-Carmona, M, Calandra, B, Le Fur, G, Casellas, P

“…Cannabinoids, known for their psychoactive effects, also possess immunomodulatory properties. The recent isolation and cloning of the G-protein-coupled…”
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Biologically active A-chain of the plant toxin ricin expressed from a synthetic gene in Escherichia coli by Shire, D, Bourrié, B J, Carillon, C, Derocq, J M, Dousset, P, Dumont, X, Jansen, F K, Kaghad, M, Legoux, R, Lelong, P

“…To assess the biological activity and pharmacokinetic properties of nonglycosylated ricin A-chain (RA), we have obtained the polypeptide following expression…”
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Translational research and Cancer Plan by Vassal, G, Borella, L, Pierre, A, Pamphile, R, Bourrie, B, Meflah, K, Amalric, F, Pauporte, I, Caillot, J-L, Formstecher, P, Demers, B, Dumontet, C, Grégoire, M, Lethiec, F, Boue, A-M, Tonelli, D, Pilsudski, R, Van Hijfte, L, Cailliot, C, Vrignaud, P, Merlin, J-L, Oudet, P, Arnoux, P-Y, Lassale, C

“…The French Cancer Plan 2003-2007 has made translational research central to its research programme, to ensure the care-research continuum and the quickest…”
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The Neuroprotective Agent SR 57746A Abrogates Experimental Autoimmune Encephalomyelitis and Impairs Associated Blood-Brain Barrier Disruption: Implications for Multiple Sclerosis Treatment by Bourrié, Bernard, Bribes, Estelle, Esclangon, Martine, Garcia, Laurent, Marchand, Jean, Thomas, Corinne, Maffrand, Jean-Pierre, Casellas, Pierre

“…Experimental autoimmune encephalomyelitis (EAE) is a T cell autoimmune disorder that is a widely used animal model for multiple sclerosis (MS) and, as in MS,…”
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Kinetics of cytotoxicity induced by immunotoxins. Enhancement by lysosomotropic amines and carboxylic ionophores by Casellas, P, Bourrie, B J, Gros, P, Jansen, F K

“…The kinetics of cytotoxicity induced by ricin and a series of immunotoxins consisting of ricin A-chain coupled to antibodies against cell-surface antigens has…”
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A sigma ligand, SR 31747A, potently modulates Staphylococcal enterotoxin B‐induced cytokine production in mice by BOURRIÉ, B., BENOÎT, J.‐M., DEROCQ, J.‐M., ESCLANGON, M., THOMAS, C., LE FUR, G., CASELLAS, P.

“…Sigma receptors originally described in distinct regions of the central nervous system are expressed on cells of the immune system. A sigma ligand, SR 31747A,…”
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Recherche translationnelle et plan Cancer by VASSAL, G, BORELLA, L, DEMERS, B, DUMONTET, C, GREGOIRE, M, LETHIEC, F, BOUE, A.-M, TONELLI, D, PILSUDSKI, R, VAN HIJFTE, L, CAILLIOT, C, VRIGNAUD, P, PIERRE, A, MERLIN, J.-L, OUDET, P, ARNOUX, P.-Y, LASSALE, C, PAMPHILE, R, BOURRIE, B, MEFLAH, K, AMALRIC, F, PAUPORTE, I, CAILLOT, J.-L, FORMSTECHER, P

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T-lymphocyte killing by T101-ricin A-chain immunotoxin: pH-dependent potentiation with lysosomotropic amines by CASELLAS, P, RAVEL, S, BOURRIE, B. J. P, DEROCQ, J.-M, JANSEN, F. K, LAURENT, G, GROS, P

“…To maximize T-lymphocyte killing with anti-pan-T-lymphocyte immunotoxin (IT), prepared by linking ricin A-chain to monoclonal antibody (MoAb) T101 (T101-RTA…”
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In vivo effects of a new immunosuppressive sigma ligand, SR 31747, on mouse thymus by Carayon, P, Petitpretre, G, Bourrie, B, Le Fur, G, Casellas, P

“…SR 31747 is a new sigma ligand which has immunosuppressive properties. The immunopharmacology of SR 31747 was investigated in vivo by studying its effects on…”
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The sigma ligand SR 31747 prevents the development of acute graft-versus-host disease in mice by blocking IFN-γ and GM-CSF mRNA expression by Carayon, P., Bouaboula, M., Loubet, J.F., Bourrie, B., Petitpretre, G., Le Fur, G., Casellas, P.

“…SR 31747 is a sigma ligand which prevents the development of acute graft-versus-host reaction (GvHR) in hybrid B6D2F1 mice injected with C57BL/6 parental…”
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Ligands of the peripheral benzodiazepine receptor have therapeutic effects in pneumopathies in vivo by Bribes, Estelle, Bourrie, Bernard, Casellas, Pierre

“…In this study, we documented the effects of different peripheral benzodiazepine receptor (PBR) ligands: PK 11195, Ro5-4864 and the newly described SSR 180575…”
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Toxin selection and modification: utilization of the A chain of ricin by Jansen, F K, Bourrie, B, Casellas, P, Dussossoy, D, Gros, O, Vic, P, Vidal, H, Gros, P

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