Search Results - "Bourne, Lucie E."

Inhibition of arterial medial calcification and bone mineralization by extracellular nucleotides: The same functional effect mediated by different cellular mechanisms by Patel, Jessal J., Zhu, Dongxing, Opdebeeck, Britt, D'Haese, Patrick, Millán, José L., Bourne, Lucie E., Wheeler‐Jones, Caroline P.D., Arnett, Timothy R., MacRae, Vicky E., Orriss, Isabel R.

“…Arterial medial calcification (AMC) is thought to share some outward similarities to skeletal mineralization and has been associated with the…”
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The effects of physiological and injurious hydrostatic pressure on murine ex vivo articular and growth plate cartilage explants: an RNAseq study by Bourne, Lucie E, Hesketh, Andrew, Sharma, Aikta, Bucca, Giselda, Bush, Peter G, Staines, Katherine A

“…Chondrocytes are continuously exposed to loads placed upon them. Physiological loads are pivotal to the maintenance of articular cartilage health, while…”
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Sexually dimorphic effects of prenatal alcohol exposure on the murine skeleton by Bourne, Lucie E, Jayash, Soher N, Michels, Lysanne V, Hopkinson, Mark, Guppy, Fergus M, Clarkin, Claire E, Gard, Paul, Brissett, Nigel, Staines, Katherine A

“…Prenatal alcohol exposure (PAE) can result in lifelong disabilities known as foetal alcohol spectrum disorder (FASD) and is associated with childhood growth…”
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Regulation of mineralisation in bone and vascular tissue: a comparative review by Bourne, Lucie E, Wheeler-Jones, Caroline PD, Orriss, Isabel R

“…Biomineralisation, the deposition of mineral onto a matrix, can be both a physiological and pathological process. Bone formation involves the secretion of an…”
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Differing calcification processes in cultured vascular smooth muscle cells and osteoblasts by Patel, Jessal J., Bourne, Lucie E., Davies, Bethan K., Arnett, Timothy R., MacRae, Vicky E., Wheeler-Jones, Caroline PD, Orriss, Isabel R.

“…Arterial medial calcification (AMC) is the deposition of calcium phosphate mineral, often as hydroxyapatite, in the medial layer of the arteries. AMC shares…”
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2‐Oxothiazolidine‐4‐carboxylic acid inhibits vascular calcification via induction of glutathione synthesis by Patel, Jessal J., Bourne, Lucie E., Thakur, Shori, Farrington, Ken, Gorog, Diana A., Orriss, Isabel R., Baydoun, Anwar R.

“…Arterial medial calcification (AMC), the deposition of hydroxyapatite in the medial layer of the arteries, is a known risk factor for cardiovascular events…”
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Evidence that pyrophosphate acts as an extracellular signalling molecule to exert direct functional effects in primary cultures of osteoblasts and osteoclasts by Bourne, Lucie E., Davies, Bethan K., Millan, Jose Luis, Arnett, Timothy R., Wheeler-Jones, Caroline P.D., Keen, Jacob A.C., Roberts, Scott J., Orriss, Isabel R.

“…Extracellular pyrophosphate (PPi) is well known for its fundamental role as a physiochemical mineralisation inhibitor. However, information about its direct…”
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Modulation of osteoblast differentiation and function by the P2X4 receptor by Orriss, Isabel R., Davies, Bethan K., Bourne, Lucie E., Arnett, Timothy R.

“…Bone cells are known to express multiple P2 receptor subtypes, and the functional effects of receptor activation have been described for many of these. One…”
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N‐acetylcysteine (NAC) differentially affects arterial medial calcification and bone formation: The role of l‐cysteine and hydrogen sulphide by Bourne, Lucie E., Patel, Jessal J., Davies, Bethan K., Neven, Ellen, Verhulst, Anja, D'Haese, Patrick C., Wheeler‐Jones, Caroline P. D., Orriss, Isabel R.

“…Arterial medial calcification (AMC) is the deposition of calcium phosphate in the arteries. AMC is widely thought to share similarities with physiological bone…”
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Inhibition of vascular smooth muscle cell calcification by ATP analogues by Patel, Jessal J., Bourne, Lucie E., Millán, José Luis, Arnett, Timothy R., MacRae, Vicky E., Wheeler-Jones, Caroline P. D., Orriss, Isabel R.

“…Arterial medial calcification (AMC) has been associated with phenotypic changes in vascular smooth muscle cells (VSMCs) that reportedly makes them more…”
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