Search Results - "Bourjot, Mélanie"
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Prostratin and 12‑O‑Tetradecanoylphorbol 13-Acetate Are Potent and Selective Inhibitors of Chikungunya Virus Replication
Published in Journal of natural products (Washington, D.C.) (28-12-2012)“…A chemical study of the Vietnamese plant species Trigonostemon howii led to the isolation of a new tigliane-type diterpenoid, trigowiin A (1), along with…”
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Antibacterial Compounds from Mushrooms: A Lead to Fight ESKAPEE Pathogenic Bacteria?
Published in Planta medica (01-04-2021)“…Infectious diseases are among the greatest threats to global health in the 21st century, and one critical concern is due to antibiotic resistance developed by…”
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3
Thin‐layer chromatography‐bioautographic method for the detection of arginase inhibitors
Published in Journal of separation science (01-06-2020)“…Arginase represents a promising therapeutic target for various pathologies including inflammatory, cardiovascular, and parasitic diseases or cancers. In the…”
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4
Trigocherrierin A, a potent inhibitor of chikungunya virus replication
Published in Molecules (Basel, Switzerland) (24-03-2014)“…Trigocherrierin A (1) and trigocherriolide E (2), two new daphnane diterpenoid orthoesters (DDOs), and six chlorinated analogues, trigocherrins A, B, F and…”
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5
Antiviral chlorinated daphnane diterpenoid orthoesters from the bark and wood of Trigonostemon cherrieri
Published in Phytochemistry (Oxford) (01-12-2012)“…The chemical investigation of the bark and wood of Trigonostemon cherrieri (Euphorbiaceae) led to the isolation of ten chlorinated daphnane diterpenoid…”
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Targeting bioactive compounds in natural extracts - Development of a comprehensive workflow combining chemical and biological data
Published in Analytica chimica acta (06-09-2019)“…In natural product drug discovery, several strategies have emerged to highlight specifically bioactive compound(s) within complex mixtures (fractions or crude…”
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Screening for Antibacterial Activity of French Mushrooms against Pathogenic and Multidrug Resistant Bacteria
Published in Applied sciences (01-05-2022)“…In the alarming context of antibiotic resistance, we explored the antibacterial potential of French mushrooms against wild-type and multidrug-resistant (MDR)…”
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8
Flacourtosides A–F, Phenolic Glycosides Isolated from Flacourtia ramontchi
Published in Journal of natural products (Washington, D.C.) (27-04-2012)“…In an effort to identify novel inhibitors of chikungunya (CHIKV) and dengue (DENV) virus replication, a systematic study with 820 ethyl acetate extracts of…”
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9
Automatised pharmacophoric deconvolution of plant extracts - application to Cinchona bark crude extract
Published in Faraday discussions (15-08-2019)“…We present a development of the "Plasmodesma" dereplication method [Margueritte et al., Magn. Reson. Chem., 2018, 56, 469]. This method is based on the…”
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10
Targeted discovery of bioactive natural products using a pharmacophoric deconvolution strategy: Proof of principle with eleganolone from Bifurcaria bifurcata R. Ross
Published in Phytochemistry letters (01-08-2018)“…[Display omitted] •Pharmacophoric deconvolution accelerates the discovery of bioactive molecules.•The proof of principle is performed with eleganolone from…”
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11
Automatic differential analysis of NMR experiments in complex samples
Published in Magnetic resonance in chemistry (01-06-2018)“…Liquid state nuclear magnetic resonance (NMR) is a powerful tool for the analysis of complex mixtures of unknown molecules. This capacity has been used in many…”
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12
Antiplasmodial, antitrypanosomal, and cytotoxic activities of prenylated flavonoids isolated from the stem bark of Artocarpus styracifolius
Published in Planta medica (01-10-2010)“…In continuation of our efforts to find new antimalarial drugs, a systematic IN VITRO evaluation using a chloroquine resistant strain of PLASMODIUM FALCIPARUM…”
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13
Triterpenoids from Acacia ataxacantha DC: antimicrobial and antioxidant activities
Published in BMC complementary and alternative medicine (12-08-2016)“…Acacia ataxacantha is a medicinal specie used extensively in traditional medicine of Benin republic to treat infectious diseases. Our previous study showed…”
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14
Chemical constituents of Anacolosa pervilleana and their antiviral activities
Published in Fitoterapia (01-09-2012)“…In an effort to identify novel inhibitors of Chikungunya (CHIKV) and Dengue (DENV) virus replication, a systematic study with 820 ethyl acetate extracts of…”
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15
Acthaside: a new chromone derivative from Acacia ataxacantha and its biological activities
Published in BMC complementary and alternative medicine (07-12-2016)“…Acacia ataxacantha (Fabaceae), used in traditional medicine grows in the South-West of Bénin. Ethyl acetate extract of the barks of this species was previously…”
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16
Automatic differential analysis of NMR experiments in complex samples
Published 27-07-2017“…Liquid state NMR is a powerful tool for the analysis of complex mixtures of unknown molecules. This capacity has been used in many analytical approaches:…”
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