Search Results - "Bourgeois, Natasha M"
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The structural basis of flagellin detection by NAIP5: A strategy to limit pathogen immune evasion
Published in Science (American Association for the Advancement of Science) (17-11-2017)“…Robust innate immune detection of rapidly evolving pathogens is critical for host defense. Nucleotide-binding domain leucine-rich repeat (NLR) proteins…”
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Protein Kinase A Negatively Regulates the Acetic Acid Stress Response in S. cerevisiae
Published in Microorganisms (Basel) (17-07-2024)“…Bioethanol fermentation from lignocellulosic hydrolysates is negatively affected by the presence of acetic acid. The budding yeast adapts to acetic acid stress…”
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Multiple receptor tyrosine kinases regulate dengue infection of hepatocytes
Published in Frontiers in cellular and infection microbiology (2024)“…Dengue is an arboviral disease causing severe illness in over 500,000 people each year. Currently, there is no way to constrain dengue in the clinic. Host…”
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Dengue activates mTORC2 signaling to counteract apoptosis and maximize viral replication
Published in Frontiers in cellular and infection microbiology (12-09-2022)“…The mechanistic target of rapamycin (mTOR) functions in two distinct complexes: mTORC1, and mTORC2. mTORC1 has been implicated in the pathogenesis of…”
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Maternal HIV status skews transcriptomic response in infant cord blood monocytes exposed to Bacillus Calmette--Guerín
Published in AIDS (London) (01-01-2021)“…OBJECTIVES:HIV-exposed uninfected (HEU) infants exhibit altered vaccine responses and an increased mortality compared with HIV-unexposed infants. Here, vaccine…”
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Maternal HIV status skews transcriptomic response in infant cord blood monocytes exposed to BCG
Published in AIDS (London) (01-01-2021)Get full text
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