Search Results - "Bourdon, Mario A."

Investigation into the Mechanism(s) That Leads to Platelet Decreases in Cynomolgus Monkeys During Administration of ISIS 104838, a 2ʹ-MOE-Modified Antisense Oligonucleotide by Narayanan, Padmakumar, Shen, Lijiang, Curtis, Brian R, Bourdon, Mario A, Nolan, John P, Gupta, Shipra, Hoffmaster, Christine, Zhou, Fangli, Christian, Bryan, Schaubhut, Jayne L, Greenlee, Sarah, Burel, Sebastien A, Witztum, Joe L, Engelhardt, Jeffrey A, Henry, Scott P

“…Abstract ISIS 104838, a 2’-O-methoxyethyl (2’-MOE)-modified antisense oligonucleotide (ASO), causes a moderate, reproducible, dose-dependent, but selflimiting…”
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Remodeling of collagen matrix by human tumor cells requires activation and cell surface association of matrix metalloproteinase-2 by DERYUGINA, E. I, BOURDON, M. A, REISFELD, R. A, STRONGIN, A

“…We assessed the functional significance of tumor cell-associated matrix metalloproteinase (MMP)-2 in extracellular matrix remodeling compared with that of the…”
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Neutralizing anti-vascular endothelial growth factor antibody completely inhibits angiogenesis and growth of human prostate carcinoma micro tumors in vivo by Borgström, Per, Bourdon, Mario A., Hillan, Kenneth J., Sriramarao, P., Ferrara, Napoleone

“…BACKGROUND Neovascularization mediated by growth factors produced by tumors is critical for the growth of tumors. Vascular endothelial growth factor (VEGF) is…”
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Tenascin mediates human glioma cell migration and modulates cell migration on fibronectin by Deryugina, E I, Bourdon, M A

“…The role of tenascin in mediating tumor cell migration was studied using two cell migration models. In migration/invasion Transwell assays U251.3 glioma cells…”
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Functional activation of integrin ?v?3 in tumor cells expressing membrane-type 1 matrix metalloproteinase by Deryugina, Elena I., Bourdon, Mario A., Jungwirth, Karli, Smith, Jeffrey W., Strongin, Alex Y.

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Human glioma-mesenchymal extracellular matrix antigen defined by monoclonal antibody by Bourdon, M A, Wikstrand, C J, Furthmayr, H, Matthews, T J, Bigner, D D

“…The distribution and localization of a glioma-associated antigen defined by monoclonal antibody 81C6 has been examined using human cultured cell lines and…”
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Novel splice variants of human tenascin-C mRNA identified in normal and bullous keratopathy corneas by Saghizadeh, M, Khin, H L, Bourdon, M A, Kenney, M C, Ljubimov, A V

“…Pseudophakic/aphakic bullous keratopathy (PBK/ABK) human corneas accumulate an extracellular matrix glycoprotein tenascin-C (TN-C), an important modulator of…”
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Functional activation of integrin αvβ3 in tumor cells expressing membrane‐type 1 matrix metalloproteinase by Deryugina, Elena I., Bourdon, Mario A., Jungwirth, Karli, Smith, Jeffrey W., Strongin, Alex Y.

“…Matrix metalloproteinases (MMPs) and integrins have been implicated in a variety of processes involved in tumor progression. To evaluate the individual roles…”
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Tenascin: An Extracellular Matrix Protein Prominent in Specialized Embryonic Tissues and Tumors by Erickson, H P, Bourdon, M A

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Matrix metalloproteinase-2 activation modulates glioma cell migration by Deryugina, E I, Bourdon, M A, Luo, G X, Reisfeld, R A, Strongin, A

“…Stable transfection of U251.3 glioma cells with cDNA encoding MT-MMP-1 resulted in increased cell surface expression of MT-MMP-1 and TIMP-2, constitutive…”
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Endothelial cell attachment and spreading on human tenascin is mediated by α2β1 and αvβ3 integrins by SRIRAMARAO, P, MENDLER, M, BOURDON, M. A

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L-selectin and very late antigen-4 integrin promote eosinophil rolling at physiological shear rates in vivo by Sriramarao, P, von Andrian, UH, Butcher, EC, Bourdon, MA, Broide, DH

“…Adherence of eosinophils to vascular endothelium and their accumulation at sites of allergen challenge are hallmarks of allergic inflammation. However, the…”
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Tumor cell invasion through matrigel is regulated by activated matrix metalloproteinase-2 by Deryugina, E I, Luo, G X, Reisfeld, R A, Bourdon, M A, Strongin, A

“…We tested the hypothesis that there is a correlation between tumor cell efficiency in activation of matrix metalloproteinase-2 (MMP-2) and invasion through…”
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Tenascin Mediates Cell Attachment through an RGD-Dependent Receptor by Bourdon, Mario A., Ruoslahti, Erkki

“…Tenascin is an extracellular matrix glycoprotein expressed in association with mesenchymal-epithelial interactions during development and in the neovasculature…”
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A novel tenascin type III repeat is part of a complex of tenascin mRNA alternative splices by Sriramarao, P., Bourdon, Mario A.

“…Sequence analysis of two human tenascin encoding cDNA clones from a cDNA library of the U251 glloblastoma cell line revealed the presence of a novel 276 bp…”
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Expression of tenascin-C splice variants in normal and bullous keratopathy human corneas by Ljubimov, AV, Saghizadeh, M, Spirin, KS, Khin, HL, Lewin, SL, Zardi, L, Bourdon, MA, Kenney, MC

“…To characterize the expression patterns of tenascin-C (TN-C) splice variants in normal corneas and in those affected by pseudophakic-aphakic bullous…”
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Identification and Synthesis of a Recognition Signal for the Attachment of Glycosaminoglycans to Proteins by Bourdon, Mario A., Krusius, Tom, Campbell, Steven, Schwartz, Nancy B., Ruoslahti, Erkki

“…Comparison of the amino acid sequences of three different proteoglycan core proteins reveals a 12-amino acid sequence that is about 50% homologous among these…”
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Endothelial cell attachment and spreading on human tenascin is mediated by α2β1 and αVβ 3 integrins by Sriramarao, P., Mendler, Markus, Bourdon, Mario A.

“…Human umbilical vein endothelial cells were found to attach and partially spread on human tenascin. The attachment of endothelial cells to tenascin results in…”
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Tenascin expression in human glioma cell lines and normal tissues by Ventimiglia, J B, Wikstrand, C J, Ostrowski, L E, Bourdon, M A, Lightner, V A, Bigner, D D

“…Tenascin expression was evaluated in 21 human glioma cell lines and in normal adult tissue extracts by Western and Northern blotting. The cell lines differed…”
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Identification of a growth factor for primary murine stroma as macrophage colony-stimulating factor by Deryugina, EI, Ratnikov, BI, Bourdon, MA, Gilmore, GL, Shadduck, RK, Muller- Sieburg, CE

“…Knowledge of the stromal microenvironment is crucial for understanding the hematopoietic system. We took advantage of an assay that permits analysis of primary…”
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