Search Results - "Bourdon, Jérémie"
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A multi-objective constraint-based approach for modeling genome-scale microbial ecosystems
Published in PloS one (10-02-2017)“…Interplay within microbial communities impacts ecosystems on several scales, and elucidation of the consequent effects is a difficult task in ecology. In…”
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Predicting weighted unobserved nodes in a regulatory network using answer set programming
Published in BMC bioinformatics (25-08-2023)“…The impact of a perturbation, over-expression, or repression of a key node on an organism, can be modelled based on a regulatory and/or metabolic network…”
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Induction of Human Trophoblast Stem Cells from Somatic Cells and Pluripotent Stem Cells
Published in Cell reports (Cambridge) (24-11-2020)“…Human trophoblast stem cells (hTSCs) derived from blastocysts and first-trimester cytotrophoblasts offer an unprecedented opportunity to study the placenta…”
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Tuning Co-operative Energy Transfer in Copper(I) Complexes Using Two-Photon Absorbing Diimine-Based Ligand Sensitizers
Published in Angewandte Chemie International Edition (31-10-2024)“…Photocatalysis mediated by low energy light wavelengths has potential to enable safer, sustainable synthetic methods. A phenanthroline-derived ligand…”
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Integrated pseudotime analysis of human pre-implantation embryo single-cell transcriptomes reveals the dynamics of lineage specification
Published in Cell stem cell (02-09-2021)“…Understanding lineage specification during human pre-implantation development is a gateway to improving assisted reproductive technologies and stem cell…”
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Boolean Network Models of Human Preimplantation Development
Published in Journal of computational biology (01-06-2024)“…Single-cell transcriptomic studies of differentiating systems allow meaningful understanding, especially in human embryonic development and cell fate…”
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Meneco, a Topology-Based Gap-Filling Tool Applicable to Degraded Genome-Wide Metabolic Networks
Published in PLoS computational biology (01-01-2017)“…Increasing amounts of sequence data are becoming available for a wide range of non-model organisms. Investigating and modelling the metabolic behaviour of…”
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Computational Methods in Systems Biology
Published in BioSystems (01-11-2016)Get full text
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A Logic for Checking the Probabilistic Steady-State Properties of Reaction Networks
Published in Journal of computational biology (01-08-2017)“…Designing probabilistic reaction models and determining their stochastic kinetic parameters are major issues in systems biology. To assist in the construction…”
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Computational discovery of dynamic cell line specific Boolean networks from multiplex time-course data
Published in PLoS computational biology (01-10-2018)“…Protein signaling networks are static views of dynamic processes where proteins go through many biochemical modifications such as ubiquitination and…”
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Probabilistic Modeling of Microbial Metabolic Networks for Integrating Partial Quantitative Knowledge Within the Nitrogen Cycle
Published in Frontiers in microbiology (28-01-2019)“…Understanding the interactions between microbial communities and their environment sufficiently to predict diversity on the basis of physicochemical parameters…”
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Bayesian Integrative Modeling of Genome-Scale Metabolic and Regulatory Networks
Published in Informatics (Basel) (01-03-2020)“…The integration of high-throughput data to build predictive computational models of cellular metabolism is a major challenge of systems biology. These models…”
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Combinations of Cytochrome P450 Gene Polymorphisms Enhancing the Risk for Sporadic Colorectal Cancer Related to Red Meat Consumption
Published in Cancer epidemiology, biomarkers & prevention (01-07-2007)“…Susceptibility to sporadic colorectal cancers (CRC) is generally thought to be the sum of complex interactions between environmental and genetic factors, all…”
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Integrating quantitative knowledge into a qualitative gene regulatory network
Published in PLoS computational biology (01-09-2011)“…Despite recent improvements in molecular techniques, biological knowledge remains incomplete. Any theorizing about living systems is therefore necessarily…”
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Model of the delayed translation of cyclin B maternal mRNA after sea urchin fertilization
Published in Molecular reproduction and development (01-12-2016)“…SUMMARY Sea urchin eggs exhibit a cap‐dependent increase in protein synthesis within minutes after fertilization. This rise in protein synthesis occurs at a…”
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Exploring the impact of dexamethasone on gene regulation in myeloma cells
Published in Life science alliance (01-09-2023)“…Among glucocorticoids (GCs), dexamethasone (Dex) is widely used in treatment of multiple myelomas. However, despite a definite benefit, all patients relapse…”
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17
Statistical properties of factor oracles
Published in Journal of discrete algorithms (Amsterdam, Netherlands) (01-03-2011)“…Factor and suffix oracles have been introduced in Allauzen et al. (1999) [1] in order to provide an economic and efficient solution for storing all the factors…”
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Exploring metabolism flexibility in complex organisms through quantitative study of precursor sets for system outputs
Published in BMC systems biology (23-01-2014)“…When studying metabolism at the organ level, a major challenge is to understand the matter exchanges between the input and output components of the system. For…”
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Temporal constraints of a gene regulatory network: Refining a qualitative simulation
Published in BioSystems (01-12-2009)“…The modelling of gene regulatory networks (GRNs) has classically been addressed through very different approaches. Among others, extensions of Thomas’s…”
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Toward systems biology in brown algae to explore acclimation and adaptation to the shore environment
Published in Omics (Larchmont, N.Y.) (01-12-2011)“…Brown algae belong to a phylogenetic lineage distantly related to land plants and animals. They are almost exclusively found in the intertidal zone, a harsh…”
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