Search Results - "Bourdin, Bernadette"
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Antitrypanosomal Activity of Fexinidazole, a New Oral Nitroimidazole Drug Candidate for Treatment of Sleeping Sickness
Published in Antimicrobial Agents and Chemotherapy (01-12-2011)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Fexinidazole--a new oral nitroimidazole drug candidate entering clinical development for the treatment of sleeping sickness
Published in PLoS neglected tropical diseases (21-12-2010)“…Human African trypanosomiasis (HAT), also known as sleeping sickness, is a fatal parasitic disease caused by trypanosomes. Current treatment options for HAT…”
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3
Nutrition, diabetes and tuberculosis in the epidemiological transition
Published in PloS one (21-06-2011)“…Diabetes prevalence and body mass index reflect the nutritional profile of populations but have opposing effects on tuberculosis risk. Interactions between…”
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4
Fexinidazole: a potential new drug candidate for Chagas disease
Published in PLoS neglected tropical diseases (01-11-2012)“…New safe and effective treatments for Chagas disease (CD) are urgently needed. Current chemotherapy options for CD have significant limitations, including…”
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5
In vitro and in vivo experimental models for drug screening and development for Chagas disease
Published in Memórias do Instituto Oswaldo Cruz (01-03-2010)“…Chagas disease, a neglected illness, affects nearly 12-14 million people in endemic areas of Latin America. Although the occurrence of acute cases sharply has…”
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Novel 3-Nitro-1H-1,2,4-triazole-Based Aliphatic and Aromatic Amines as Anti-Chagasic Agents
Published in Journal of medicinal chemistry (08-12-2011)“…A series of novel 2-nitro-1H-imidazole- and 3-nitro-1H-1,2,4-triazole-based aromatic and aliphatic amines were screened for antitrypanosomal activity and…”
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Genotoxicity profile of fexinidazole: a drug candidate in clinical development for human African trypanomiasis (sleeping sickness)
Published in Mutagenesis (01-09-2012)“…The parasitic disease human African trypanomiasis (HAT), also known as sleeping sickness, is a highly neglected fatal condition endemic in sub-Saharan Africa,…”
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1-Aryl-4-nitro-1H-imidazoles, a new promising series for the treatment of human African trypanosomiasis
Published in European journal of medicinal chemistry (01-05-2011)“…Nitroimidazoles are a well-known class of antibacterial and antiprotozoal drugs but in spite of the widespread clinical and veterinary use of these drugs, this…”
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9
Recent Optimization Highlights of the Georgywood Process
Published in Chimia (01-09-2006)“…Alternative procedures to the industrial process by which Georgywood® is presently prepared on a multiton scale have been investigated. These give the crucial…”
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10
Novel 3-Nitro-1 H -1,2,4-triazole-Based Aliphatic and Aromatic Amines as Anti-Chagasic Agents
Published in Journal of medicinal chemistry (08-12-2011)Get full text
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11
1-Aryl-4-nitro-1 H-imidazoles, a new promising series for the treatment of human African trypanosomiasis
Published in European journal of medicinal chemistry (2011)“…Nitroimidazoles are a well-known class of antibacterial and antiprotozoal drugs but in spite of the widespread clinical and veterinary use of these drugs, this…”
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12
Fexinidazole: A Potential New Drug Candidate for Chagas Disease: e1870
Published in PLoS neglected tropical diseases (01-11-2012)“…Background New safe and effective treatments for Chagas disease (CD) are urgently needed. Current chemotherapy options for CD have significant limitations,…”
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13
Cycloaddition reactions for the synthesis of piperidine and indolizidine alkaloids
Published in Pure and applied chemistry (01-01-1997)“…Abstract…”
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14
Treating camphors with potassium in liquid ammonia leads to a double-Horeau duplication
Published in Journal of the American Chemical Society (01-02-1992)Get full text
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