Search Results - "Bourdette, D N"

Thyroid hormone and thyromimetics inhibit myelin and axonal degeneration and oligodendrocyte loss in EAE by Chaudhary, P., Marracci, G.H., Calkins, E., Pocius, E., Bensen, A.L., Scanlan, T.S., Emery, B., Bourdette, D.N.

“…We have previously demonstrated that thyromimetics stimulate oligodendrocyte precursor cell differentiation and promote remyelination in murine demyelination…”
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Clinical trial of a formal group fatigue program in multiple sclerosis by Hugos, CL, Copperman, LF, Fuller, BE, Yadav, V., Lovera, J., Bourdette, DN

“…Fatigue: Take Control is a novel program to teach fatigue management to people with multiple sclerosis (MS) following recommendations in the Fatigue and…”
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A highly immunogenic trivalent T cell receptor peptide vaccine for multiple sclerosis by Bourdette, D N, Edmonds, E, Smith, C, Bowen, J D, Guttmann, C RG, Nagy, Z P, Simon, J, Whitham, R, Lovera, J, Yadav, V, Mass, M, Spencer, L, Culbertson, N, Bartholomew, R M, Theofan, G, Milano, J, Offner, H, Vandenbark, A A

“…Background: T cell receptor (TCR) peptide vaccination is a novel approach to treating multiple sclerosis (MS). The low immunogenicity of previous vaccines has…”
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NMDA receptor encephalitis mimicking seronegative neuromyelitis optica by Kruer, M C, Koch, T K, Bourdette, D N, Chabas, D, Waubant, E, Mueller, S, Moscarello, M A, Dalmau, J, Woltjer, R L, Adamus, G

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Impact of interferon beta-1a on neurologic disability in relapsing multiple sclerosis by RUDICK, R. A, GOODKIN, D. E, ALAM, J. J, SIMONIAN, N. A, CAMPION, M. K, BARTOSZAK, D. M, BOURDETTE, D. N, BRAIMAN, J, BROWNSCHEIDLE, C. M, COATS, M. E, COHAN, S. L, DOUGHERTY, D. S, JACOBS, L. D, KINKEL, R. P, MASS, M. K, MUNSCHAUER, F. E, PRIORE, R. L, PULLICINO, P. M, SCHEROKMAN, B. J, WEISTOCK-GUTTMAN, B, WHITHAM, R. H, COOKFAIR, D. L, HERNDON, R. M, RICHERT, J. R, SALAZAR, A. M, FISCHER, J. S, GRANGER, C. V, SIMON, J. H

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Selective depletion of myelin-reactive T cells with the anti-OX-40 antibody ameliorates autoimmune encephalomyelitis by Weinberg, A.D, Bourdette, D.N, Sullivan, T.J, Lemon, M, Wallin, J.J, Maziarz, R, Davey, M, Palida, F, Godfrey, W, Engleman, E, Fulton, R.J, Offner, H, Vandenbark, A.A

“…The OX-40 protein was selectively upregulated on encephalitogenic myelin basic protein (MBP)-specific T cells at the site of inflammation during the onset of…”
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Rudimentary TCR Signaling Triggers Default IL-10 Secretion by Human Th1 Cells by Burrows, Gregory G, Chou, Yuan K, Wang, Chunhe, Chang, Justin W, Finn, Thomas P, Culbertson, Nicole E, Kim, Joseph, Bourdette, Dennis N, Lewinsohn, Deborah A, Lewinsohn, David M, Ikeda, Masayuki, Yoshioka, Tohru, Allen, Charles N, Offner, Halina, Vandenbark, Arthur A

“…Understanding the process of inducing T cell activation has been hampered by the complex interactions between APC and inflammatory Th1 cells. To dissociate…”
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Design, engineering and production of functional single-chain T cell receptor ligands by Burrows, G.G., Chang, J.W., Bächinger, H-P., Bourdette, D.N., Offner, H., Vandenbark, A.A.

“…Major histocompatibility complex (MHC) class II molecules are membrane-anchored heterodimers on the surface of antigen presenting cells (APCs) that bind the T…”
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Lipoic acid stimulates cAMP production in T lymphocytes and NK cells by Schillace, R.V., Pisenti, N., Pattamanuch, N., Galligan, S., Marracci, G.H., Bourdette, D.N., Carr, D.W.

“…The anti-oxidant lipoic acid (LA) potently suppresses clinical and pathologic disease in the animal model of multiple sclerosis, experimental autoimmune…”
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Lipoic acid inhibits expression of ICAM-1 and VCAM-1 by CNS endothelial cells and T cell migration into the spinal cord in experimental autoimmune encephalomyelitis by Chaudhary, Priya, Marracci, Gail H., Bourdette, Dennis N.

“…Lipoic acid (LA) suppresses and treats murine experimental autoimmune encephalomyelitis (EAE), which models multiple sclerosis. However, the mechanisms by…”
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Frequency of T cells specific for myelin basic protein and myelin proteolipid protein in blood and cerebrospinal fluid in multiple sclerosis by Chou, Y K, Bourdette, D N, Offner, H, Whitham, R, Wang, R Y, Hashim, G A, Vandenbark, A A

“…T cell sensitization to two myelin components, myelin basic protein (MBP) and myelin proteolipid protein (PLP), may be important to the pathogenesis of…”
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NMDA RECEPTOR ENCEPHALITIS MIMICKING SERONEGATIVE NEUROMYELITIS OPTICA by KRUER, M. C, KOCH, T. K, BOURDETTE, D. N, CHABAS, D, WAUBANT, E, MUELLER, S, MOSCARELLO, M. A, DALMAU, J, WOLTJER, R. L, ADAMUS, G

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Target organ-specific up-regulation of the MRC OX-40 marker and selective production of Th1 lymphokine mRNA by encephalitogenic T helper cells isolated from the spinal cord of rats with experimental autoimmune encephalomyelitis by Weinberg, AD, Wallin, JJ, Jones, RE, Sullivan, TJ, Bourdette, DN, Vandenbark, AA, Offner, H

“…Lewis x Buffalo F1 rat lymphocytes express both forms of the allelic marker RT7.1 (Lewis) and RT7.2 (Buffalo). We generated myelin basic protein (MBP)-specific…”
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T Lymphocytes Promote the Development of Bone Marrow-Derived APC in the Central Nervous System by Subramanian, Sandhya, Bourdette, Dennis N, Corless, Christopher, Vandenbark, Arthur A, Offner, Halina, Jones, Richard E

“…Certain cells within the CNS, microglial cells and perivascular macrophages, develop from hemopoietic myelomonocytic lineage progenitors in the bone marrow…”
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Gulf War Unexplained Illnesses: Persistence and Unexplained Nature of Self-Reported Symptoms by McCauley, Linda A., Joos, Sandra K., Lasarev, Michael R., Storzbach, Daniel, Bourdette, Dennis N.

“…Most published reports of health symptoms among Gulf War (GW) veterans have been based on self-reported questionnaire data. The presence of these symptoms at…”
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Lymphocytes from SJL/J mice immunized with spinal cord respond selectively to a peptide of proteolipid protein and transfer relapsing demyelinating experimental autoimmune encephalomyelitis by WHITHAM, R. H, BOURDETTE, D. N, HASHIM, G. A, HERNDON, R. M, ILG, R. C, VANDENBARK, A. A, OFFNER, H

“…Relapsing experimental autoimmune encephalomyelitis (R-EAE) can be induced in SJL/J mice by immunization with spinal cord homogenate and adjuvant. The specific…”
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Impact of interferon beta-1a on neurologic disability in relapsing multiple sclerosis: Multiple sclerosis by RUDICK, R. A, GOODKIN, D. E, ALAM, J. J, SIMONIAN, N. A, CAMPION, M. K, BARTOSZAK, D. M, BOURDETTE, D. N, BRAIMAN, J, BROWNSCHEIDLE, C. M, COATS, M. E, COHAN, S. L, DOUGHERTY, D. S, JACOBS, L. D, KINKEL, R. P, MASS, M. K, MUNSCHAUER, F. E, PRIORE, R. L, PULLICINO, P. M, SCHEROKMAN, B. J, WEISTOCK-GUTTMAN, B, WHITHAM, R. H, COOKFAIR, D. L, HERNDON, R. M, RICHERT, J. R, SALAZAR, A. M, FISCHER, J. S, GRANGER, C. V, SIMON, J. H

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Myelin basic protein specific T cell lines and clones derived from the CNS of rats with EAE only recognize encephalitogenic epitopes by Bourdette, D N, Vainiene, M, Morrison, W, Jones, R, Turner, M J, Hashim, G A, Vandenbark, A A, Offner, H

“…The epitope specificities of myelin basic protein (BP) specific T cell lines derived from the spinal cords (SC) and lymph nodes (LN) of rats with experimental…”
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Dysregulation of the hypothalamic–pituitary–gonadal axis in experimental autoimmune encephalomyelitis and multiple sclerosis by Foster, Scott C., Daniels, Crystal, Bourdette, Dennis N., Bebo, Bruce F.

“…The ability of sex hormones to regulate cytokine production is well established, but the ability of cytokines to regulate sex hormone production has only begun…”
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Episodic changes in T-cell frequencies to myelin basic protein in patients with multiple sclerosis by VANDENBARK, A. A, BOURDETTE, D. N, WHITHAM, R, CHOU, Y. K, HASHIM, G. A, OFFNER, H

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