Search Results - "Bourbon, Laura M. L"

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    Which Three-Dimensional Characteristics Make Efficient Inhibitors of Protein–Protein Interactions?

    Which Three-Dimensional Characteristics Make Efficient Inhibitors of Protein–Protein Interactions? by Kuenemann, Mélaine A, Bourbon, Laura M. L, Labbé, Céline M, Villoutreix, Bruno O, Sperandio, Olivier

    “…The specific properties of protein–protein interactions (PPI) (flat, large and hydrophobic) make them harder to tackle with low-molecular-weight compounds…”
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    An exploration of the 3D chemical space has highlighted a specific shape profile for the compounds intended to inhibit protein-protein interactions

    An exploration of the 3D chemical space has highlighted a specific shape profile for the compounds intended to inhibit protein-protein interactions by Kuenemann, Mélaine A, Bourbon, Laura ML, Labbé, Céline M, Villoutreix, Bruno O, Sperandio, Olivier

    Published in BMC bioinformatics (13-02-2015)
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