Search Results - "Boulware, Stephen"
-
1
Distinct Mechanisms of Nuclease-Directed DNA-Structure-Induced Genetic Instability in Cancer Genomes
Published in Cell reports (Cambridge) (30-01-2018)“…Sequences with the capacity to adopt alternative DNA structures have been implicated in cancer etiology; however, the mechanisms are unclear. For example,…”
Get full text
Journal Article -
2
Triplex-forming oligonucleotides targeting c-MYC potentiate the anti-tumor activity of gemcitabine in a mouse model of human cancer
Published in Molecular carcinogenesis (01-09-2014)“…Antimetabolite chemotherapy remains an essential cancer treatment modality, but often produces only marginal benefit due to the lack of tumor specificity, the…”
Get full text
Journal Article -
3
-
4
2,6-Dithiopurine, a nucleophilic scavenger, protects against mutagenesis in mouse skin treated in vivo with 2-(chloroethyl) ethyl sulfide, a mustard gas analog
Published in Toxicology and applied pharmacology (01-09-2012)“…Sulfur mustard [bis(2-chloroethyl)sulfide, SM] is a well-known DNA-damaging agent that has been used in chemical warfare since World War I, and is a weapon…”
Get full text
Journal Article -
5
2,6-Dithiopurine Blocks Toxicity and Mutagenesis in Human Skin Cells Exposed to Sulfur Mustard Analogues, 2-Chloroethyl Ethyl Sulfide and 2-Chloroethyl Methyl Sulfide
Published in Chemical research in toxicology (15-03-2010)“…Sulfur mustard (bis-(2-chloroethyl)sulfide) is a well-known chemical warfare agent that induces debilitating cutaneous toxicity in exposed individuals. It is…”
Get full text
Journal Article -
6
Relationship between the genotype profiles of paraoxonase (PON-1) and urinary organophosphate excretion
Published 01-01-2005“…While a number of studies have evaluated exposure matrices for children, limited data are available to define the relationship between gene expression and…”
Get full text
Dissertation -
7
Relationship between the genotype profiles of paraoxonase (PON-1) and urinary organophosphate excretion
Get full text
Dissertation