Search Results - "Boulton, M"

Diagnostic utility of corneal confocal microscopy and intra-epidermal nerve fibre density in diabetic neuropathy by Alam, Uazman, Jeziorska, Maria, Petropoulos, Ioannis N, Asghar, Omar, Fadavi, Hassan, Ponirakis, Georgios, Marshall, Andrew, Tavakoli, Mitra, Boulton, Andrew J M, Efron, Nathan, Malik, Rayaz A

“…Corneal confocal microscopy (CCM) is a rapid, non-invasive, reproducible technique that quantifies small nerve fibres. We have compared the diagnostic…”
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The 'Green Revolution' dwarfing genes play a role in disease resistance in Triticum aestivum and Hordeum vulgare by Saville, R. J., Gosman, N., Burt, C. J., Makepeace, J., Steed, A., Corbitt, M., Chandler, E., Brown, J. K. M., Boulton, M. I., Nicholson, P.

“…The Green Revolution dwarfing genes, Rht-B1b and Rht-D1b, encode mutant forms of DELLA proteins and are present in most modern wheat varieties. DELLA proteins…”
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Diabetic Foot Disease during the COVID-19 Pandemic by Boulton, Andrew J M

“…Throughout 2020, the COVID-19 pandemic has had a major impact on the care of non-communicable diseases across the world and diabetes is no exception. Whereas…”
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Corneal confocal microscopy for identification of diabetic sensorimotor polyneuropathy: a pooled multinational consortium study by Perkins, Bruce A., Lovblom, Leif E., Bril, Vera, Scarr, Daniel, Ostrovski, Ilia, Orszag, Andrej, Edwards, Katie, Pritchard, Nicola, Russell, Anthony, Dehghani, Cirous, Pacaud, Danièle, Romanchuk, Kenneth, Mah, Jean K., Jeziorska, Maria, Marshall, Andrew, Shtein, Roni M., Pop-Busui, Rodica, Lentz, Stephen I., Boulton, Andrew J. M., Tavakoli, Mitra, Efron, Nathan, Malik, Rayaz A.

“…Aims/hypothesis Small cohort studies raise the hypothesis that corneal nerve abnormalities (including corneal nerve fibre length [CNFL]) are valid non-invasive…”
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Boundary spanning and identity work in the clinical research delivery workforce: a qualitative study of research nurses, midwives and allied health professionals in the National Health Service, United Kingdom by McNiven, A, Boulton, M, Locock, L, Hinton, L

“…Research nurses, midwives and allied health professionals are members of an important emergent profession delivering clinical research and, in the United…”
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The diabetic foot in 2015: an overview by Markakis, K., Bowling, F. L., Boulton, A. J. M.

“…In 2015, it can be said that the diabetic foot is no longer the Cinderella of diabetic complications. Thirty years ago there was little evidence‐based research…”
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Mechanisms and Management of Diabetic Painful Distal Symmetrical Polyneuropathy by TESFAYE, Solomon, BOULTON, Andrew J. M, DICKENSON, Anthony H

“…Although a number of the diabetic neuropathies may result in painful symptomatology, this review focuses on the most common: chronic sensorimotor distal…”
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Canadian experience with the pipeline embolization device for repair of unruptured intracranial aneurysms by O'Kelly, C J, Spears, J, Chow, M, Wong, J, Boulton, M, Weill, A, Willinsky, R A, Kelly, M, Marotta, T R

“…Flow-diverting stents, such as the PED, have emerged as a novel means of treating complex intracranial aneurysms. This retrospective analysis of the initial…”
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Greater corneal nerve loss at the inferior whorl is related to the presence of diabetic neuropathy and painful diabetic neuropathy by Kalteniece, Alise, Ferdousi, Maryam, Petropoulos, Ioannis, Azmi, Shazli, Adam, Safwaan, Fadavi, Hassan, Marshall, Andrew, Boulton, Andrew J. M., Efron, Nathan, Faber, Catharina G., Lauria, Giuseppe, Soran, Handrean, Malik, Rayaz A.

“…We assessed whether a measure of more distal corneal nerve fibre loss at the inferior whorl(IW) region is better than proximal measures of central corneal…”
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RANKL–OPG and RAGE modulation in vascular calcification and diabetes: novel targets for therapy by Ndip, Agbor, Wilkinson, Fiona L., Jude, Edward B., Boulton, Andrew J. M., Alexander, M. Yvonne

“…Type 2 diabetes is associated with increased cardiovascular morbidity and mortality and early vascular ageing. This takes the form of atherosclerosis, with…”
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The global burden of diabetic foot disease by Boulton, Andrew JM, Vileikyte, Loretta, Ragnarson-Tennvall, Gunnel, Apelqvist, Jan

“…Diabetic foot problems are common throughout the world, resulting in major economic consequences for the patients, their families, and society. Foot ulcers are…”
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Identifying spatial heterogeneity in vaccination coverage in Michigan from 2008–2018: Evaluating the impact of a 2015 policy change on measles risk by Masters, N., Zelner, J., Delamater, P., Boulton, M.

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Factors associated with intentional and unintentional non‐adherence to adjuvant endocrine therapy following breast cancer by Brett, J., Fenlon, D., Boulton, M., Hulbert‐Williams, N.J., Walter, F.M., Donnelly, P., Lavery, B., Morgan, A., Morris, C., Watson, E.

“…Adherence to adjuvant endocrine therapy (AET) following breast cancer is known to be suboptimal despite its known efficacy in reducing recurrence and…”
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Corneal Confocal Microscopy Detects Neuropathy in Subjects With Impaired Glucose Tolerance by ASGHAR, Omar, PETROPOULOS, Ioannis N, MALIK, Rayaz A, ALAM, Uazman, JONES, Wendy, JEZIORSKA, Maria, MARSHALL, Andrew, PONIRAKIS, Georgios, FADAVI, Hassan, BOULTON, Andrew J. M, TAVAKOLI, Mitra

“…Impaired glucose tolerance (IGT) represents one of the earliest stages of glucose dysregulation and is associated with macrovascular disease, retinopathy, and…”
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Painful diabetic peripheral neuropathy: consensus recommendations on diagnosis, assessment and management by Tesfaye, S., Vileikyte, L., Rayman, G., Sindrup, S. H., Perkins, B. A., Baconja, M., Vinik, A. I., Boulton, A. J. M.

“…Painful diabetic peripheral neuropathy (DPN) is common, is associated with significant reduction in quality of life and poses major treatment challenges to the…”
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Dysregulation of macrophage development and phenotype in diabetic human macrophages can be rescued by Hoxa3 protein transduction by Alrdahe, Salma, Al Sadoun, Hadeel, Torbica, Tanja, McKenzie, Edward A, Bowling, Frank L, Boulton, Andrew J M, Mace, Kimberly A

“…Controlled inflammatory responses of myeloid cells recruited to wounds are essential for effective repair. In diabetes, the inflammatory response is prolonged…”
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Whither pathogenetic treatments for diabetic polyneuropathy? by Boulton, Andrew J. M., Kempler, Peter, Ametov, Alexander, Ziegler, Dan

“…Summary Diabetic distal symmetric polyneuropathy (DSPN) occurs in around one‐third of patients with diabetes and is associated with significant morbidity and…”
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Reduced Lower-Limb Muscle Strength and Volume in Patients With Type 2 Diabetes in Relation to Neuropathy, Intramuscular Fat, and Vitamin D Levels by Almurdhi, Monirah M, Reeves, Neil D, Bowling, Frank L, Boulton, Andrew J M, Jeziorska, Maria, Malik, Rayaz A

“…Muscle weakness and atrophy of the lower limbs may develop in patients with diabetes, increasing their risk of falls. The underlying basis of these…”
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The pathogenesis of diabetic retinopathy: old concepts and new questions by CAI, J, BOULTON, M

“…Hyperglycaemia appears to be a critical factor in the aetiology of diabetic retinopathy and initiates downstream events including: basement membrane…”
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Corneal Nerve Loss Detected With Corneal Confocal Microscopy Is Symmetrical and Related to the Severity of Diabetic Polyneuropathy by PETROPOULOS, Ioannis N, ALAM, Uazman, FADAVI, Hassan, ASGHAR, Omar, GREEN, Patrick, PONIRAKIS, Georgios, MARSHALL, Andrew, BOULTON, Andrew J. M, TAVAKOLI, Mitra, MALIK, Rayaz A

“…To establish if corneal nerve loss, detected using in vivo corneal confocal microscopy (IVCCM), is symmetrical between right and left eyes and relates to the…”
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