Search Results - "Boulos, Hala"

Validation of a liquid biopsy assay with molecular and clinical profiling of circulating tumor DNA by Finkle, Justin D., Boulos, Hala, Driessen, Terri M., Lo, Christine, Blidner, Richard A., Hafez, Ashraf, Khan, Aly A., Lozac’hmeur, Ariane, McKinnon, Kelly E., Perera, Jason, Zhu, Wei, Dowlati, Afshin, White, Kevin P., Tell, Robert, Beaubier, Nike

“…Liquid biopsy is a valuable precision oncology tool that is increasingly used as a non-invasive approach to identify biomarkers, detect resistance mutations,…”
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Tissue- and strain-specific effects of a genotoxic carcinogen 1,3-butadiene on chromatin and transcription by Israel, Jennifer W., Chappell, Grace A., Simon, Jeremy M., Pott, Sebastian, Safi, Alexias, Lewis, Lauren, Cotney, Paul, Boulos, Hala S., Bodnar, Wanda, Lieb, Jason D., Crawford, Gregory E., Furey, Terrence S., Rusyn, Ivan

“…Epigenetic effects of environmental chemicals are under intense investigation to fill existing knowledge gaps between environmental/occupational exposures and…”
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Greater than two coexisting mutations in KRAS and NRAS identified in the circulating tumor DNA fraction of liquid biopsies by NGS and confirmed with ddPCR by Boulos, Hala, Tell, Robert, Beaubier, Nike, Blidner, Richard

“…Abstract only e15563 Background: Liquid biopsies are increasingly utilized as a non-invasive tool in precision oncology to assess tumor mutational profiles in…”
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Abstract 3106: Accurate estimation of circulating tumor DNA fraction from ultra low-pass whole-genome sequencing by Finkle, Justin, Lo, Christine, Boulos, Hala, Driessen, Terri, Zhu, Wei, Tell, Robert

“…Early detection of recurrence is critical to improve the survival of cancer patients. Blood-based “liquid biopsies” provide a minimally invasive method to…”
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Functional constraints on the constitutive androstane receptor inferred from human sequence variation and cross-species comparisons by Thompson, Emma E, Kuttab-Boulos, Hala, Krasowski, Matthew D, Di Rienzo, Anna

“…Members of the NR1I subfamily of nuclear receptors play a role in the transcriptional activation of genes involved in drug metabolism and transport. NR1I3, the…”
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Predicting recurrence using a tumor-uninformed ctDNA assay detecting MRD in patients with resected stage II or III colorectal cancer: Subset analysis from the GALAXY study in CIRCULATE-Japan by Nakamura, Yoshiaki, Kaneva, Kristiyana, Lo, Christine, Neems, Daniel, Freaney, Jonathan, Boulos, Hala, Hyun, Seung Won, Oki, Eiji, Kotani, Daisuke, Wantanabe, Jun, Kotaka, Masahito, Bando, Hideaki, Yamazaki, Kentaro, Takemasa, Ichiro, Kato, Takeshi, Sangli, Chithra, Blidner, Richard, Sasser, Kate, Nimeiri, Halla, Yoshino, Takayuki

“…21 Background: The presence of circulating tumor DNA (ctDNA) after curative-intent surgery can identify patients with minimal residual disease (MRD) who are at…”
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A tumor-naive ctDNA assay detects minimal residual disease in resected stage II or III colorectal cancer and predicts recurrence: subset analysis from the GALAXY study in CIRCULATE-Japan by Nakamura, Yoshiaki, Kaneva, Kristiyana, Lo, Christine, Neems, Daniel, Freaney, Jonathan E., Boulos, Hala, Hyun, Seung Won, Islam, Farahnaz, Yamada-Hanff, Jason, Driessen, Terri M., Sonnenschein, Anne, DeSantis, Dana F., Kotani, Daisuke, Watanabe, Jun, Kotaka, Masahito, Mishima, Saori, Bando, Hideaki, Yamazaki, Kentaro, Taniguchi, Hiroya, Takemasa, Ichiro, Kato, Takeshi, Sangli, Chithra, Tell, Robert, Blidner, Richard, Yoshino, Takayuki, Sasser, Kate, Oki, Eiji, Nimeiri, Halla

“…Purpose: Analysis of circulating tumor DNA (ctDNA) may enable early identification of patients likely to relapse, presenting an opportunity for early…”
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Tissue- and strain-specific effects of a genotoxic carcinogen1,3-butadiene on chromatin and transcription by Israel, Jennifer W., Chappell, Grace A., Simon, Jeremy M., Pott, Sebastian, Safi, Alexias, Lewis, Lauren, Cotney, Paul, Boulos, Hala S., Bodnar, Wanda, Lieb, Jason D., Crawford, Gregory E., Furey, Terrence S., Rusyn, Ivan

“…Epigenetic effects of environmental chemicals are under intense investigation to fill existing knowledge gaps between environmental/occupational exposures and…”
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Mutations in zinc finger 407 [ZNF407] cause a unique autosomal recessive cognitive impairment syndrome by Kambouris, Marios, Maroun, Rachid C, Ben-Omran, Tawfeg, Al-Sarraj, Yasser, Errafii, Khaoula, Ali, Rehab, Boulos, Hala, Curmi, Patrick A, El-Shanti, Hatem

“…A consanguineous Arab family is affected by an apparently novel autosomal recessive disorder characterized by cognitive impairment, failure-to-thrive,…”
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Biallelic SCN10A mutations in neuromuscular disease and epileptic encephalopathy by Kambouris, Marios, Thevenon, Julien, Soldatos, Ariane, Cox, Allison, Stephen, Joshi, Ben‐Omran, Tawfeg, Al‐Sarraj, Yasser, Boulos, Hala, Bone, William, Mullikin, James C., Masurel‐Paulet, Alice, St‐Onge, Judith, Dufford, Yannis, Chantegret, Corrine, Thauvin‐Robinet, Christel, Al‐Alami, Jamil, Faivre, Laurence, Riviere, Jean Baptiste, Gahl, William A., Bassuk, Alexander G., Malicdan, May Christine V., El‐Shanti, Hatem

“…Objectives Two consanguineous families, one of Sudanese ethnicity presenting progressive neuromuscular disease, severe cognitive impairment, muscle weakness,…”
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Haplotype structure of the UDP-glucuronosyltransferase 1A1 promoter in different ethnic groups by INNOCENTI, Federico, GRIMSLEY, Carrie, DAS, Soma, RAMIREZ, Jacqueline, CHENG CHENG, KUTTAB-BOULOS, Hala, RATAIN, Mark J, DI RIENZO, Anna

“…Genetic variation in UDP-glucuronosyltransferase 1A1 (UGT1A1)expression has several important clinical implications. UGT1A1 basal transcription is affected by…”
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Biallelic SCN 10A mutations in neuromuscular disease and epileptic encephalopathy by Kambouris, Marios, Thevenon, Julien, Soldatos, Ariane, Cox, Allison, Stephen, Joshi, Ben‐Omran, Tawfeg, Al‐Sarraj, Yasser, Boulos, Hala, Bone, William, Mullikin, James C., Masurel‐Paulet, Alice, St‐Onge, Judith, Dufford, Yannis, Chantegret, Corrine, Thauvin‐Robinet, Christel, Al‐Alami, Jamil, Faivre, Laurence, Riviere, Jean Baptiste, Gahl, William A., Bassuk, Alexander G., Malicdan, May Christine V., El‐Shanti, Hatem

“…ObjectivesTwo consanguineous families, one of Sudanese ethnicity presenting progressive neuromuscular disease, severe cognitive impairment, muscle weakness,…”
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